EP0399972A1 - Rührer zur aseptischen Verwendung - Google Patents

Rührer zur aseptischen Verwendung Download PDF

Info

Publication number: EP0399972A1
Authority: EP; European Patent Office
Prior art keywords: impeller; vessel; blade; rotation; cylindrical recess
Prior art date: 1989-05-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP90850180A

Other languages

English (en)

French (fr)

Other versions

EP0399972B1 (de

Inventor

Nils Arthun

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

roplan International AB

Roplan International AB

Original Assignee

Steridose Systems AB

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-26

Filing date

1990-05-17

Publication date

1990-11-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20376064&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP0399972(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-05-17 Application filed by Steridose Systems AB filed Critical Steridose Systems AB

1990-11-28 Publication of EP0399972A1 publication Critical patent/EP0399972A1/de

1993-04-21 Application granted granted Critical

1993-04-21 Publication of EP0399972B1 publication Critical patent/EP0399972B1/de

2010-05-17 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

239000012530 fluid Substances 0.000 claims abstract description 15
238000004140 cleaning Methods 0.000 claims abstract description 11
238000003756 stirring Methods 0.000 claims abstract description 7
230000001939 inductive effect Effects 0.000 claims abstract description 3
230000002093 peripheral effect Effects 0.000 claims description 5
230000001954 sterilising effect Effects 0.000 description 3
238000004659 sterilization and disinfection Methods 0.000 description 2
230000008878 coupling Effects 0.000 description 1
238000010168 coupling process Methods 0.000 description 1
238000005859 coupling reaction Methods 0.000 description 1
239000003814 drug Substances 0.000 description 1
238000000034 method Methods 0.000 description 1
239000000203 mixture Substances 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
230000002035 prolonged effect Effects 0.000 description 1
230000001105 regulatory effect Effects 0.000 description 1
229910001220 stainless steel Inorganic materials 0.000 description 1
239000010935 stainless steel Substances 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Images

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
- B01F33/453—Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements
- B01F33/4535—Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements using a stud for supporting the stirring element
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
- B01F33/453—Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/40—Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
- B01F35/41—Mounting or supporting stirrer shafts or stirrer units on receptacles
- B01F35/411—Mounting or supporting stirrer shafts or stirrer units on receptacles by supporting only one extremity of the shaft
- B01F35/4112—Mounting or supporting stirrer shafts or stirrer units on receptacles by supporting only one extremity of the shaft at the bottom of the receptacle, e.g. by studs

Definitions

the object of the invention is thus to provide an impeller with a considerably greater self-cleaning capability so that sterilization with steam or other fluids can occur in a considerably shorter time.
the bearing means includes a stub-axle centrally located on an end wall of an inwardly extending cylindrical recess in the vessel's bottom wall.
the bearing- and drive means of the impeller are shown in figure 2 and include an inwardly-directed cylindrical recess 12 in the vessel wall 11, the recess being welded in such a way that no opening or inlets occur in this section of the tank wall.
the impeller 10 is rotatably supported by means of a bush 10a on a stub axle 13 which is centrally located on an end wall 14, which demarcates the cylindrical recess 12.
the impeller 10 is, like the vessel 11, principally manufactured from acidproof stainless steel, with a number of angled blades 15 and a central lifting ring 16.
the impeller presents a peripheral section 17 which surrounds the cylindrical recess 12 and contains a number of permanent magnets 18 which are inductively connected to a corresponding number of permanent magnets 19 which are located in a rotor 20.
This rotor is arranged to be driven in the direction of arrow 21 (see figure 1) by a (not shown) conventional electric motor, whereby the impeller 10 surrounding the recess is caused to rotate.
the passages and the orifices can be greater or fewer in number.
the device for driving the impeller can be differently designed.

Landscapes

Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Mixers Of The Rotary Stirring Type (AREA)
Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Food-Manufacturing Devices (AREA)
Thermally Insulated Containers For Foods (AREA)
Materials For Medical Uses (AREA)
Prostheses (AREA)
Accessories For Mixers (AREA)

EP90850180A 1989-05-26 1990-05-17 Rührer zur aseptischen Verwendung Expired - Lifetime EP0399972B1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE8901877A SE463750B (sv)	1989-05-26	1989-05-26	Omroerare foer aseptiska aendamaal, vilken aer vridbar i en foerutbestaemd rotationsriktning genom induktiva drivorgan inuti en tank
SE8901877		1989-05-26

Publications (2)

Publication Number	Publication Date
EP0399972A1 true EP0399972A1 (de)	1990-11-28
EP0399972B1 EP0399972B1 (de)	1993-04-21

Family

ID=20376064

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP90850180A Expired - Lifetime EP0399972B1 (de)	1989-05-26	1990-05-17	Rührer zur aseptischen Verwendung

Country Status (8)

Country	Link
EP (1)	EP0399972B1 (de)
AT (1)	ATE88374T1 (de)
DE (1)	DE69001388T2 (de)
DK (1)	DK0399972T3 (de)
ES (1)	ES2041522T3 (de)
FI (1)	FI92475C (de)
NO (1)	NO169326C (de)
SE (1)	SE463750B (de)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0590473A1 (de) *	1992-10-01	1994-04-06	Mavag Verfahrenstechnik Ag	Impeller zum Rühren von sterilen Flüssigkeiten
DE4232934A1 (de) *	1992-10-01	1994-04-07	Mavag Verfahrenstechnik Ag Alt	Doppel-Impeller zum Rühren von sterilen Flüssigkeiten
US5533803A (en) *	1992-10-01	1996-07-09	Mavag Verfahrenstechnik Ag	Magnetic stirring apparatus with contactless coupling between stirring shaft and stirring tool
US5758965A (en) *	1996-12-05	1998-06-02	General Signal Corporation	Mixer system
US5779359A (en) *	1996-12-05	1998-07-14	General Signal Corporation	Mixer having exposed clean-in-place bearing assemblies
US6065865A (en) *	1998-06-05	2000-05-23	Mixel	Magnetically driven agitator with magnetic rotation detector
US6206562B1 (en) *	1998-01-28	2001-03-27	Mixel	Agitator with adjustable magnetic drive coupling
CN100340329C (zh) *	2004-10-29	2007-10-03	中国石油化工股份有限公司	自引气式气液混合叶轮
WO2008088371A2 (en) *	2006-06-16	2008-07-24	Xcellerex, Inc.	Gas delivery configurations, foam control systems, and bag molding methods and articles for collapsible bag vessels and bioreactors
EP2196688A2 (de)	2005-07-29	2010-06-16	zeta AG Bioprocess Systems	Magnetrührer
GB2440474B (en) *	2005-04-05	2011-01-05	Per-Olof K Andersson	Ultraclean magnetic mixer
AT518668B1 (de) *	2017-01-25	2017-12-15	Zeta Biopharma Gmbh	Rührwerk für einen Rührbehälter

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK3659700T3 (da) *	2018-11-29	2022-06-13	Alfa Laval Corp Ab	Magnetisk koblet væskeblander
CN111167295A (zh) *	2020-01-15	2020-05-19	邓智超	一种地下工程施工用酸性气体净化装置
CN116510596B (zh) *	2023-06-29	2023-09-29	中科圣杰(深圳)科技集团有限公司	一种无菌投料工作站

Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3138167A (en) *	1963-06-18	1964-06-23	Sprout Waldron & Co Inc	Mixer for feeds and the like
DE2511717A1 (de) *	1974-03-21	1975-09-25	Paul Raess	Belueftungspropeller
EP0053759A2 (de) *	1980-12-10	1982-06-16	Friedrich Walter Dr. Herfeld	Mischvorrichtung und Verfahren zum Reinigen derselben
EP0148738A1 (de) *	1983-12-08	1985-07-17	Boliden Aktiebolag	Verfahren und Vorrichtung für die Verteilung von Wasserreinigungschemikalien

1989
- 1989-05-26 SE SE8901877A patent/SE463750B/sv not_active IP Right Cessation
1990
- 1990-05-17 AT AT90850180T patent/ATE88374T1/de not_active IP Right Cessation
- 1990-05-17 ES ES199090850180T patent/ES2041522T3/es not_active Expired - Lifetime
- 1990-05-17 DE DE90850180T patent/DE69001388T2/de not_active Expired - Fee Related
- 1990-05-17 EP EP90850180A patent/EP0399972B1/de not_active Expired - Lifetime
- 1990-05-17 DK DK90850180.2T patent/DK0399972T3/da active
- 1990-05-17 FI FI902451A patent/FI92475C/fi not_active IP Right Cessation
- 1990-05-25 NO NO902321A patent/NO169326C/no unknown

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3138167A (en) *	1963-06-18	1964-06-23	Sprout Waldron & Co Inc	Mixer for feeds and the like
DE2511717A1 (de) *	1974-03-21	1975-09-25	Paul Raess	Belueftungspropeller
EP0053759A2 (de) *	1980-12-10	1982-06-16	Friedrich Walter Dr. Herfeld	Mischvorrichtung und Verfahren zum Reinigen derselben
EP0148738A1 (de) *	1983-12-08	1985-07-17	Boliden Aktiebolag	Verfahren und Vorrichtung für die Verteilung von Wasserreinigungschemikalien

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0590473A1 (de) *	1992-10-01	1994-04-06	Mavag Verfahrenstechnik Ag	Impeller zum Rühren von sterilen Flüssigkeiten
DE4232936A1 (de) *	1992-10-01	1994-04-07	Mavag Verfahrenstechnik Ag Alt	Impeller zum Rühren von sterilen Flüssigkeiten
DE4232934A1 (de) *	1992-10-01	1994-04-07	Mavag Verfahrenstechnik Ag Alt	Doppel-Impeller zum Rühren von sterilen Flüssigkeiten
EP0599010A1 (de) *	1992-10-01	1994-06-01	Mavag Verfahrenstechnik Ag	Doppel-Impeller zum Rühren von sterilen Flüssigkeiten
US5393142A (en) *	1992-10-01	1995-02-28	Mavag Verfahrenstechnik Ag	Impeller for stirring sterile liquids
US5407272A (en) *	1992-10-01	1995-04-18	Mavag Verfahrenstechnik Ag.	Double impeller for stirring sterile liquids
US5533803A (en) *	1992-10-01	1996-07-09	Mavag Verfahrenstechnik Ag	Magnetic stirring apparatus with contactless coupling between stirring shaft and stirring tool
US5758965A (en) *	1996-12-05	1998-06-02	General Signal Corporation	Mixer system
US5779359A (en) *	1996-12-05	1998-07-14	General Signal Corporation	Mixer having exposed clean-in-place bearing assemblies
US6206562B1 (en) *	1998-01-28	2001-03-27	Mixel	Agitator with adjustable magnetic drive coupling
US6065865A (en) *	1998-06-05	2000-05-23	Mixel	Magnetically driven agitator with magnetic rotation detector
CN100340329C (zh) *	2004-10-29	2007-10-03	中国石油化工股份有限公司	自引气式气液混合叶轮
GB2440474B (en) *	2005-04-05	2011-01-05	Per-Olof K Andersson	Ultraclean magnetic mixer
EP2196688A2 (de)	2005-07-29	2010-06-16	zeta AG Bioprocess Systems	Magnetrührer
US8128277B2 (en)	2005-07-29	2012-03-06	Zeta Biopharma Gmbh	Magnetic agitator
WO2008088371A2 (en) *	2006-06-16	2008-07-24	Xcellerex, Inc.	Gas delivery configurations, foam control systems, and bag molding methods and articles for collapsible bag vessels and bioreactors
WO2008088371A3 (en) *	2006-06-16	2009-04-09	Xcellerex Inc	Gas delivery configurations, foam control systems, and bag molding methods and articles for collapsible bag vessels and bioreactors
US9908664B2 (en)	2006-06-16	2018-03-06	Ge Healthcare Bio-Sciences Corp.	Method of forming a collapsible bag using a mold and mandrel
US11008138B2 (en)	2006-06-16	2021-05-18	Global Life Sciences Solutions Usa Llc	Method of forming a collapsible bag using a mold and mandrel
US11312539B2 (en)	2006-06-16	2022-04-26	Global Life Sciences Solutions Usa Llc	Method of forming a collapsible bag using a mold and mandrel
AT518668B1 (de) *	2017-01-25	2017-12-15	Zeta Biopharma Gmbh	Rührwerk für einen Rührbehälter
AT518668A4 (de) *	2017-01-25	2017-12-15	Zeta Biopharma Gmbh	Rührwerk für einen Rührbehälter

Also Published As

Publication number	Publication date
NO169326C (no)	1992-06-10
ES2041522T3 (es)	1993-11-16
SE8901877L (sv)	1990-11-27
FI92475B (fi)	1994-08-15
DK0399972T3 (da)	1993-08-09
NO169326B (no)	1992-03-02
SE463750B (sv)	1991-01-21
FI902451A0 (fi)	1990-05-17
DE69001388T2 (de)	1993-10-21
DE69001388D1 (de)	1993-05-27
NO902321D0 (no)	1990-05-25
NO902321L (no)	1990-11-27
EP0399972B1 (de)	1993-04-21
SE8901877D0 (sv)	1989-05-26
ATE88374T1 (de)	1993-05-15
FI92475C (fi)	1994-11-25

Legal Events

Date	Code	Title	Description
1990-10-13	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
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Publication	Publication Date	Title
EP0399972B1 (de)	1993-04-21	Rührer zur aseptischen Verwendung
US4993841A (en)	1991-02-19	Magnetic impeller means for a mixing vessel
US5478149A (en)	1995-12-26	Magnetic mixer
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