EP0252951A4 - Technetium-antikörper konjugate. - Google Patents
Technetium-antikörper konjugate.Info
- Publication number
- EP0252951A4 EP0252951A4 EP19870900623 EP87900623A EP0252951A4 EP 0252951 A4 EP0252951 A4 EP 0252951A4 EP 19870900623 EP19870900623 EP 19870900623 EP 87900623 A EP87900623 A EP 87900623A EP 0252951 A4 EP0252951 A4 EP 0252951A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- technetium
- antibody conjugate
- conjugate
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPH410386 | 1986-01-06 | ||
AU4103/86 | 1986-01-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0252951A1 EP0252951A1 (de) | 1988-01-20 |
EP0252951A4 true EP0252951A4 (de) | 1988-09-07 |
Family
ID=3771433
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19870900623 Withdrawn EP0252951A4 (de) | 1986-01-06 | 1987-01-06 | Technetium-antikörper konjugate. |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP0252951A4 (de) |
WO (1) | WO1987004164A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4877868A (en) * | 1986-03-12 | 1989-10-31 | Neorx Corporation | Radionuclide antibody coupling |
US5460785A (en) * | 1989-08-09 | 1995-10-24 | Rhomed Incorporated | Direct labeling of antibodies and other protein with metal ions |
US5346687A (en) * | 1989-08-09 | 1994-09-13 | Rhomed Incorporated | Direct radiolabeling of antibody against stage specific embryonic antigen for diagnostic imaging |
US5078985A (en) * | 1989-08-09 | 1992-01-07 | Rhomed, Incorporated | Radiolabeling antibodies and other proteins with technetium or rhenium by regulated reduction |
CA2065299C (en) * | 1989-08-09 | 2001-07-24 | Buck A. Rhodes | Direct radiolabeling of antibodies and other proteins with technetium or rhenium |
US5326856A (en) * | 1992-04-09 | 1994-07-05 | Cytogen Corporation | Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding |
US6080384A (en) * | 1997-03-25 | 2000-06-27 | American Biogenetic Sciences, Inc. | Methods for radionuclide-labeling of biomolecules and kits utilizing the same |
DE19845798A1 (de) * | 1998-09-29 | 2000-04-13 | Schering Ag | Verwendung von Neoangiogenese-Markern für Diagnose und Therapie von Tumoren, diese enthaltende Mittel, sowie Verfahren zu deren Herstellung |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0028092A2 (de) * | 1979-10-29 | 1981-05-06 | University Patents, Inc. | Zusammensetzung, die einen radiomarkierten Antikörper enthält, Ausrüstung zu ihrer Herstellung und Ausrüstung zur Krebs- oder Tumorbestimmung, die diese Zusammensetzung enthält |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4323546A (en) * | 1978-05-22 | 1982-04-06 | Nuc Med Inc. | Method and composition for cancer detection in humans |
US4486538A (en) * | 1978-07-07 | 1984-12-04 | Samuel Bogoch | Detection of malignant tumor cells |
FR2437213A1 (fr) * | 1978-09-28 | 1980-04-25 | Cm Ind | Produits cytotoxiques formes par liaison covalente de la chaine a de la ricine avec un anticorps et leur procede de preparation |
FR2516794B1 (fr) * | 1981-11-20 | 1985-10-25 | Sanofi Sa | Nouveaux medicaments anticancereux pour le traitement des leucemies t constitues de la chaine a de la ricine et d'un anticorps monoclonal specifique |
FR2523445A1 (fr) * | 1982-03-17 | 1983-09-23 | Sanofi Sa | Nouveaux conjugues associant, par liaison covalente, une enzyme et un anticorps, et associations medicamenteuses utilisant lesdits conjugues |
AU565669B2 (en) * | 1983-12-29 | 1987-09-24 | Commonwealth Of Australia, The | Preparation of 99m-tc radiopharmaceuticals |
EP0179872B1 (de) * | 1984-04-23 | 1991-06-19 | Boston Biomedical Research Institute, Inc. | Doppelspezifische antikörper-determinanten |
-
1987
- 1987-01-06 EP EP19870900623 patent/EP0252951A4/de not_active Withdrawn
- 1987-01-06 WO PCT/AU1987/000004 patent/WO1987004164A1/en not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0028092A2 (de) * | 1979-10-29 | 1981-05-06 | University Patents, Inc. | Zusammensetzung, die einen radiomarkierten Antikörper enthält, Ausrüstung zu ihrer Herstellung und Ausrüstung zur Krebs- oder Tumorbestimmung, die diese Zusammensetzung enthält |
Non-Patent Citations (3)
Title |
---|
CHEMICAL ABSTRACTS, Vol. 104, No. 18, 5th May 1986, page 449, Abstract No. 155935y, Columbus, Ohio, US, J. BALDAS et al.: "Effect of the technetium-nitrido group on the behavior of technetium-99m-radio-pharmaceuticals". * |
International Journal of Applied Radiation and Isotopes, Vol. 36, No. 2, February 1985, pages 133-139, Oxford, GB, J. BALDAS et al.: "Substitution reactions of 99mTcNC14 - a route to a new class of 99mTc-radiopharmaceuticals". * |
See also references of WO8704164A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO1987004164A1 (en) | 1987-07-16 |
EP0252951A1 (de) | 1988-01-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19870904 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19880907 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN |
|
18W | Application withdrawn |
Withdrawal date: 19890407 |
|
R18W | Application withdrawn (corrected) |
Effective date: 19890407 |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: MCKENZIE, IAN, FARQUHAR, CAMPBELL Inventor name: KANELLOS, JERRY Inventor name: PIETERSZ, GEOFFREY, ALLAN |