EP0105834A3 - Verfahren und Einrichtung zum Uebertragen einer flüssigen Probe in Mikro- und Millilitermengen - Google Patents

Verfahren und Einrichtung zum Uebertragen einer flüssigen Probe in Mikro- und Millilitermengen Download PDF

Info

Publication number
EP0105834A3
EP0105834A3 EP83810382A EP83810382A EP0105834A3 EP 0105834 A3 EP0105834 A3 EP 0105834A3 EP 83810382 A EP83810382 A EP 83810382A EP 83810382 A EP83810382 A EP 83810382A EP 0105834 A3 EP0105834 A3 EP 0105834A3
Authority
EP
European Patent Office
Prior art keywords
transition
millilitre
microlitre
aggregates
transferring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP83810382A
Other languages
English (en)
French (fr)
Other versions
EP0105834A2 (de
Inventor
Rudolf Oberli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GREINER INSTRUMENTS AG
Original Assignee
Greiner Electronic AG
GREINER INSTRUMENTS AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Greiner Electronic AG, GREINER INSTRUMENTS AG filed Critical Greiner Electronic AG
Publication of EP0105834A2 publication Critical patent/EP0105834A2/de
Publication of EP0105834A3 publication Critical patent/EP0105834A3/de
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/441—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)

Abstract

In einer Kolbenspritze (1) sitzt im Uebergang (8) zwi­ schen Zylinder (2) und Kanüle (4) ein ferromagnetischer Profilkörper (9) mit vielfältigen Funktionen: Beim Einsaugen einer Flüssigkeit verhindert er Turbulenzen im Uebergang (8) und die damit verbundene Bildung von Gasblasen; beim Ausstossen hilft er, Schmutz im Uebergang (8) nach unten wegzuspülen; dazwischen wirkt er durch von aussen veran­ lasste Vertikalbewegungen als Magnetrührer.
Diese Funktionen werden unterstützt durch eine schräg ansteigende Kolgenstirnfläche (13), im Zusammenwirken mit einer seitlichen Oeffnung (5), welche mit einer Entsorgungs­ einrichtung in Verbindung steht.
Hauptanwendung: Schnelles, blasenfreies und daher mengengenaues Uebertragen flüssiger Proben, z.B. Blutplas­ ma, in mehrere Prozessgefässe von Analyseautomaten.
EP83810382A 1982-09-07 1983-08-25 Verfahren und Einrichtung zum Uebertragen einer flüssigen Probe in Mikro- und Millilitermengen Withdrawn EP0105834A3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH5307/82 1982-09-07
CH530782 1982-09-07

Publications (2)

Publication Number Publication Date
EP0105834A2 EP0105834A2 (de) 1984-04-18
EP0105834A3 true EP0105834A3 (de) 1984-10-10

Family

ID=4291396

Family Applications (1)

Application Number Title Priority Date Filing Date
EP83810382A Withdrawn EP0105834A3 (de) 1982-09-07 1983-08-25 Verfahren und Einrichtung zum Uebertragen einer flüssigen Probe in Mikro- und Millilitermengen

Country Status (3)

Country Link
US (1) US4526046A (de)
EP (1) EP0105834A3 (de)
JP (1) JPS5965722A (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4711766A (en) * 1984-07-09 1987-12-08 Standard Oil Company (Indiana) Apparatus for mixing cracking catalyst with a fluid hydrocarbon
US4836037A (en) * 1986-12-16 1989-06-06 Ciba-Geigy Corporation Sample metering valve for a sample preparation system
ATE80325T1 (de) * 1987-03-02 1992-09-15 Ionode Pty Ltd Mischungsgeraet und -verfahren.
JP2648944B2 (ja) * 1988-10-20 1997-09-03 東亜医用電子株式会社 流体回路ユニット
JP2839560B2 (ja) * 1989-07-10 1998-12-16 株式会社日立製作所 粒子懸濁液混合装置，粒子懸濁液混合方法及び粒子計測装置
GB2249171A (en) * 1990-10-25 1992-04-29 N Proizv Ob Biolog Priborostro Liquid sampling
US5646049A (en) * 1992-03-27 1997-07-08 Abbott Laboratories Scheduling operation of an automated analytical system
EP1537915A3 (de) * 1992-03-27 2006-05-24 Abbott Laboratories Reaktionsbehalter
US5376313A (en) * 1992-03-27 1994-12-27 Abbott Laboratories Injection molding a plastic assay cuvette having low birefringence
US5635364A (en) * 1992-03-27 1997-06-03 Abbott Laboratories Assay verification control for an automated analytical system
US5578494A (en) * 1992-03-27 1996-11-26 Abbott Laboratories Cap actuator for opening and closing a container
US5610069A (en) * 1992-03-27 1997-03-11 Abbott Laboratories Apparatus and method for washing clinical apparatus
US5605665A (en) * 1992-03-27 1997-02-25 Abbott Laboratories Reaction vessel
US5575978A (en) * 1992-03-27 1996-11-19 Abbott Laboratories Sample container segment assembly
US5536471A (en) * 1992-03-27 1996-07-16 Abbott Laboratories Syringe with bubble flushing
US6190617B1 (en) 1992-03-27 2001-02-20 Abbott Laboratories Sample container segment assembly
US5960160A (en) * 1992-03-27 1999-09-28 Abbott Laboratories Liquid heater assembly with a pair temperature controlled electric heating elements and a coiled tube therebetween
US5540890A (en) * 1992-03-27 1996-07-30 Abbott Laboratories Capped-closure for a container
US5507410A (en) * 1992-03-27 1996-04-16 Abbott Laboratories Meia cartridge feeder
US5627522A (en) * 1992-03-27 1997-05-06 Abbott Laboratories Automated liquid level sensing system
DE4315363C1 (de) * 1993-05-08 1994-10-20 Kernforschungsz Karlsruhe Mischkammer
JP3115501B2 (ja) * 1994-06-15 2000-12-11 プレシジョン・システム・サイエンス株式会社 分注機を利用した磁性体の脱着制御方法及びこの方法によって処理される各種装置
DE4423878A1 (de) * 1994-07-07 1996-01-11 Boehringer Mannheim Gmbh Vorrichtung und Verfahren zum Abscheiden von magnetischen Mikropartikeln
CN1114831C (zh) * 1995-03-20 2003-07-16 准确***科学株式会社 利用吸移管装置处理液体的方法以及用于该法的仪器
US6759014B2 (en) * 2001-01-26 2004-07-06 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US6913934B2 (en) * 1998-08-13 2005-07-05 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US6296452B1 (en) 2000-04-28 2001-10-02 Agilent Technologies, Inc. Microfluidic pumping
EP1151806B1 (de) * 2000-05-01 2007-08-22 FUJIFILM Corporation Vorrichtung zur Abgabe eines Fluids
WO2002066151A2 (en) * 2001-01-26 2002-08-29 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
JP2005522679A (ja) 2002-04-12 2005-07-28 インストゥルメンテイション ラボラトリー カンパニー イムノアッセイプローブ
US7396512B2 (en) 2003-11-04 2008-07-08 Drummond Scientific Company Automatic precision non-contact open-loop fluid dispensing
US8211386B2 (en) 2004-06-08 2012-07-03 Biokit, S.A. Tapered cuvette and method of collecting magnetic particles
FR2972646B1 (fr) * 2011-03-14 2015-02-27 Total Sa Melange d'un fluide multiphase
US9333471B2 (en) * 2012-04-11 2016-05-10 STAT—Diagnostica & Innovation, S.L. Fluidically integrated magnetic bead beater
DE102016225209A1 (de) 2016-12-15 2018-06-21 Hamilton Bonaduz Ag Pipettiervorrichtung zur verbesserten impulsartigen Flüssigkeitspipettierung
CN115155687B (zh) * 2022-09-06 2022-11-08 广州达安基因股份有限公司 一种定量加样装置及微流控检测设备

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2156083A1 (de) * 1971-11-11 1973-05-17 Matti Reunanen Verfahren und vorrichtung zur dosierung bzw. abteilung und umsetzung bzw. inkubation von reagenzien und entnahme von proben der reaktionsmischung
US3831618A (en) * 1972-12-22 1974-08-27 Abbott Lab Apparatus for the precision metering of fluids
US3972683A (en) * 1974-06-07 1976-08-03 Hycel, Inc. Fluid transfer apparatus
US3985165A (en) * 1975-07-11 1976-10-12 G. D. Searle & Co. Dosing apparatus

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US620066A (en) * 1899-02-21 Paul weissgerber
US2129502A (en) * 1935-09-20 1938-09-06 Chicago Television & Res Lab I Liquid distribution apparatus
US3716338A (en) * 1968-06-14 1973-02-13 Hycel Inc Sample fluid dispensing apparatus for chemical testing apparatus
US3622279A (en) * 1968-06-14 1971-11-23 Hycel Inc Automatic chemical testing apparatus
US3864979A (en) * 1973-03-30 1975-02-11 Becton Dickinson Co Blood sedimentation tube barrier
DE2848535C2 (de) * 1978-11-09 1982-12-02 Walter Sarstedt Kunststoff-Spritzgußwerk, 5223 Nümbrecht Blutaufnahmevorrichtung
DK143719C (da) * 1979-01-03 1982-03-08 Radiometer As Fremgangsmaade til udluftning af en vaeskedoserende stempelpumpe og stempelpumpe med et arrangement til brug ved udoevelse affremgangsmaaden
JPS58129366A (ja) * 1982-01-29 1983-08-02 Olympus Optical Co Ltd 分配分注方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2156083A1 (de) * 1971-11-11 1973-05-17 Matti Reunanen Verfahren und vorrichtung zur dosierung bzw. abteilung und umsetzung bzw. inkubation von reagenzien und entnahme von proben der reaktionsmischung
US3831618A (en) * 1972-12-22 1974-08-27 Abbott Lab Apparatus for the precision metering of fluids
US3972683A (en) * 1974-06-07 1976-08-03 Hycel, Inc. Fluid transfer apparatus
US3985165A (en) * 1975-07-11 1976-10-12 G. D. Searle & Co. Dosing apparatus

Also Published As

Publication number Publication date
EP0105834A2 (de) 1984-04-18
JPS5965722A (ja) 1984-04-14
US4526046A (en) 1985-07-02

Similar Documents

Publication Publication Date Title
EP0105834A3 (de) Verfahren und Einrichtung zum Uebertragen einer flüssigen Probe in Mikro- und Millilitermengen
DE3688159T2 (de) Kombinierter Wasch- und Saugapparat.
DE19534955C2 (de) Chemischer Analysator mit nicht eintauchendem Rührwerk
EP0849584B1 (de) Vorrichtung (Küvette) zur Aufnahme und Speicherung von Flüssigkeiten und zur Durchführung optischer Messungen
US4730631A (en) Probe wash station
CA2019519A1 (en) New and improved, ultra low carryover sample liquid analysis apparatus and method
CA2233101A1 (en) A device having process, waste and pipette tip parking chambers and a method for transferring liquids
US4799393A (en) Combined closed and open tube sampling apparatus and method
CA2103384A1 (en) Fluid probe washing apparatus and method
DE68925493T2 (de) Gerät zum Einsammeln von Blut
IL94860A0 (en) Sample liquid aspirating and dispensing probe
EP0651255A1 (de) Automatische Pipettiervorrichtung mit Reinigungseinrichtung
IE873016L (en) Device for cleaning a needle for taking liquid
DE69017334T2 (de) Sammel- und Prüfgerät für flüssige Proben.
DE69735237T2 (de) Gerät und verfahren zum waschen von zellen
DE4128698A1 (de) Analysesystem
DE69732970T2 (de) Aliquotieverfahren zur automatischen probenanalyse
DE68924890T2 (de) Vereinfachter Lysekreislauf für einen automatischen Blutanalysator.
US4865993A (en) Minimum carryover container, and analysis system incorporating the same
Fouda et al. Robotics for the bioanalytical laboratory A flexible system for the analysis of drugs in biological fluids
JPS5984453U (ja) 希釈ピペツタ−
DE3263905D1 (en) Process for the determination of the beta-lipoprotein fraction (ldl) in body fluids
DE112010000792T5 (de) Automatische Analysevorrichtung
DE69323851T2 (de) Vorrichtung zur Handhabung einer Spritze, und biologischer Analyseautomat, eine solche Vorrichtung enthaltend
JPH0783936A (ja) 理化学実験方法

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AK Designated contracting states

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

17P Request for examination filed

Effective date: 19850329

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: GREINER INSTRUMENTS AG

17Q First examination report despatched

Effective date: 19860703

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19861114

RIN1 Information on inventor provided before grant (corrected)

Inventor name: OBERLI, RUDOLF