EE9800147A - Polymorphic forms of growth hormone secretagogue - Google Patents

Polymorphic forms of growth hormone secretagogue

Info

Publication number
EE9800147A
EE9800147A EE9800147A EE9800147A EE9800147A EE 9800147 A EE9800147 A EE 9800147A EE 9800147 A EE9800147 A EE 9800147A EE 9800147 A EE9800147 A EE 9800147A EE 9800147 A EE9800147 A EE 9800147A
Authority
EE
Estonia
Prior art keywords
growth hormone
polymorphic forms
hormone secretagogue
secretagogue
polymorphic
Prior art date
Application number
EE9800147A
Other languages
Estonian (et)
Inventor
P. Draper Jerome
C. Dubost David
J. Kaufman Michael
A. Mccauley James
L. Vandrilla Jennifer
J. Varsolona Richard
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603361.8A external-priority patent/GB9603361D0/en
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of EE9800147A publication Critical patent/EE9800147A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
EE9800147A 1995-10-27 1996-10-23 Polymorphic forms of growth hormone secretagogue EE9800147A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US590095P 1995-10-27 1995-10-27
GBGB9603361.8A GB9603361D0 (en) 1996-02-16 1996-02-16 Polymorphic forms of a growth hormone secretagogue
PCT/US1996/016955 WO1997015574A1 (en) 1995-10-27 1996-10-23 Polymorphic forms of a growth hormone secretagogue

Publications (1)

Publication Number Publication Date
EE9800147A true EE9800147A (en) 1998-12-15

Family

ID=26308741

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800147A EE9800147A (en) 1995-10-27 1996-10-23 Polymorphic forms of growth hormone secretagogue

Country Status (22)

Country Link
EP (1) EP1019402A1 (en)
JP (1) JP3204266B2 (en)
KR (1) KR19990067098A (en)
CN (1) CN1067687C (en)
AU (1) AU707946B2 (en)
BG (1) BG102476A (en)
BR (1) BR9611229A (en)
CA (1) CA2235371A1 (en)
CO (1) CO4770956A1 (en)
CZ (1) CZ128098A3 (en)
EA (1) EA000528B1 (en)
EE (1) EE9800147A (en)
HK (1) HK1017894A1 (en)
HU (1) HUP9902208A3 (en)
IS (1) IS4721A (en)
NO (1) NO310556B1 (en)
NZ (1) NZ321370A (en)
PL (1) PL327511A1 (en)
SK (1) SK51398A3 (en)
TR (1) TR199800726T2 (en)
WO (1) WO1997015574A1 (en)
YU (1) YU56696A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046333A (en) * 1996-10-25 2000-04-04 Merck & Co., Inc. Convergent process for the preparation of a growth hormone secretagogue
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
WO2017075535A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ258412A (en) * 1992-12-11 1997-01-29 Merck & Co Inc Spiro-fused piperidine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
EA199800335A1 (en) 1998-12-24
JP3204266B2 (en) 2001-09-04
IS4721A (en) 1998-04-21
HK1017894A1 (en) 1999-12-03
NZ321370A (en) 1999-11-29
AU7468696A (en) 1997-05-15
CZ128098A3 (en) 1998-09-16
BG102476A (en) 1999-04-30
JPH10512295A (en) 1998-11-24
BR9611229A (en) 1999-05-25
CN1205703A (en) 1999-01-20
KR19990067098A (en) 1999-08-16
CO4770956A1 (en) 1999-04-30
MX9803351A (en) 1998-09-30
NO981867D0 (en) 1998-04-24
PL327511A1 (en) 1998-12-21
YU56696A (en) 1999-09-27
AU707946B2 (en) 1999-07-22
TR199800726T2 (en) 1998-08-21
WO1997015574A1 (en) 1997-05-01
HUP9902208A2 (en) 1999-10-28
CN1067687C (en) 2001-06-27
SK51398A3 (en) 1998-12-02
NO981867L (en) 1998-06-29
EA000528B1 (en) 1999-10-28
CA2235371A1 (en) 1997-05-01
NO310556B1 (en) 2001-07-23
HUP9902208A3 (en) 2001-05-28
EP1019402A1 (en) 2000-07-19

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