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La invención se refiere a los compuestos de fórmula 1 y 2 (gráfico), y a las sales farmacéuticamente aceptables e hidratos de los mismos, en la que X1, R1, R2 y R11 son lo definido en la presente. La invención también se refiere a las composiciones farmacéuticas que contienen los compuestos de fórmulas 1 y 2 a los métodos para el tratamiento de los trastornos hiperproliferativos en un mamífero mediante la administración de los compuestos de fórmulas 1 y 2.The invention relates to the compounds of formulas 1 and 2 (graph), and to the pharmaceutically acceptable salts and hydrates thereof, where X1, R1, R2 and R11 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formulas 1 and 2 to methods for the treatment of hyperproliferative disorders in a mammal by administration of the compounds of formulas 1 and 2.
ECSP9827371998-11-111998-11-11
DERIVATIVES OF THENOPyrimidine AND THENOPyridine AS ANTI-CANCER AGENTS
ECSP982737A
(en)
DERIVATIVES OF BENZOCONDENSED HETEROARILAMIDE OF USEFUL TIENOPIRIDINS AS THERAPEUTIC AGENTS, PHARMACEUTICAL COMPOSITIONS INCLUDING THE SAME, AND METHODS FOR USE
DERIVATIVES OF ARILPIPERAZINIL-CICLOHEXIL INDOL, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM AND THE USE OF THE SAME FOR THE MANUFACTURE OF MEDICINES FOR THE TREATMENT OF DEPRESSION