AR029634A1 - USEFUL HETEROCICLIC DERIVATIVE COMPOUNDS AS ANTI-TARGET AGENTS, PHARMACEUTICAL COMPOSITION AND PROCESSING PROCEDURE - Google Patents

USEFUL HETEROCICLIC DERIVATIVE COMPOUNDS AS ANTI-TARGET AGENTS, PHARMACEUTICAL COMPOSITION AND PROCESSING PROCEDURE

Info

Publication number
AR029634A1
AR029634A1 ARP000102369A ARP000102369A AR029634A1 AR 029634 A1 AR029634 A1 AR 029634A1 AR P000102369 A ARP000102369 A AR P000102369A AR P000102369 A ARP000102369 A AR P000102369A AR 029634 A1 AR029634 A1 AR 029634A1
Authority
AR
Argentina
Prior art keywords
heterociclic
useful
pharmaceutical composition
processing procedure
derivative compounds
Prior art date
Application number
ARP000102369A
Other languages
Spanish (es)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR029634A1 publication Critical patent/AR029634A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

Se refieren a compuestos de la formula 1 y a las sales, profármacos y solvatos farmacéuticamente aceptables de los mismos, en la que Z, X, X1, R1, R2 y R3 son tal como se define en la memoria, así como también se refiere a composiciones farmacéuticas que contienen los compuestos anteriores para el tratamiento de trastornos mediados por angiogénesis en mamíferos por administracion de los compuestos anteriores.They refer to compounds of formula 1 and pharmaceutically acceptable salts, prodrugs and solvates thereof, in which Z, X, X1, R1, R2 and R3 are as defined herein, as well as refer to Pharmaceutical compositions containing the above compounds for the treatment of disorders mediated by angiogenesis in mammals by administration of the foregoing compounds.

ARP000102369A 1999-05-19 2000-05-17 USEFUL HETEROCICLIC DERIVATIVE COMPOUNDS AS ANTI-TARGET AGENTS, PHARMACEUTICAL COMPOSITION AND PROCESSING PROCEDURE AR029634A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13493399P 1999-05-19 1999-05-19

Publications (1)

Publication Number Publication Date
AR029634A1 true AR029634A1 (en) 2003-07-10

Family

ID=22465672

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000102369A AR029634A1 (en) 1999-05-19 2000-05-17 USEFUL HETEROCICLIC DERIVATIVE COMPOUNDS AS ANTI-TARGET AGENTS, PHARMACEUTICAL COMPOSITION AND PROCESSING PROCEDURE

Country Status (21)

Country Link
US (1) US6380214B1 (en)
EP (1) EP1187826B1 (en)
JP (2) JP3692041B2 (en)
AR (1) AR029634A1 (en)
AT (1) ATE349440T1 (en)
AU (1) AU4137400A (en)
BR (1) BR0010746A (en)
CA (1) CA2374247C (en)
CO (1) CO5170417A1 (en)
DE (1) DE60032601T2 (en)
DZ (1) DZ3042A1 (en)
ES (1) ES2276681T3 (en)
GT (1) GT200000069A (en)
HN (1) HN2000000051A (en)
MA (1) MA26733A1 (en)
MX (1) MXPA01011920A (en)
PA (1) PA8494101A1 (en)
PE (1) PE20010152A1 (en)
TN (1) TNSN00104A1 (en)
UY (1) UY26143A1 (en)
WO (1) WO2000071532A1 (en)

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US7626031B2 (en) * 2002-11-15 2009-12-01 Symphony Evolution, Inc. Substituted 3-(diarylmethylene)indolin-2-ones and methods of their use
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PL1717229T3 (en) * 2004-02-17 2011-11-30 Santen Pharmaceutical Co Ltd Novel cyclic compound having 4-pyridylalkylthio group having (un)substituted amino introduced therein
ES2368153T3 (en) * 2004-02-17 2011-11-14 Santen Pharmaceutical Co., Ltd. NEW CYCLIC COMPOUND PRESENTING A 4-PIRIDILALQUILTIO GROUP THAT PRESENTS AMINO (NOT) REPLACED INTRODUCED IN THE SAME.
AU2005223483B2 (en) 2004-03-18 2009-04-23 Zoetis Llc N-(1-arylpyrazol-4l)sulfonamides and their use as parasiticides
EP1751139B1 (en) 2004-04-30 2011-07-27 Bayer HealthCare LLC Substituted pyrazolyl urea derivatives useful in the treatment of cancer
BRPI0514667A (en) * 2004-08-26 2008-06-17 Pfizer Prod Inc processes for the preparation of isothiazole derivatives
JP4585978B2 (en) * 2005-03-03 2010-11-24 参天製薬株式会社 Novel cyclic compounds having a quinolylalkylthio group
EA016071B1 (en) * 2005-05-13 2012-01-30 Вирокем Фарма Инк. Compounds and methods for the treatment or prevention of flavivirus infections
US7932390B2 (en) 2006-06-29 2011-04-26 Hoffman-La Roche Inc. Substituted thieno[3,2-C]pyridine carboxylic acid derivatives
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Also Published As

Publication number Publication date
PA8494101A1 (en) 2003-09-05
DE60032601D1 (en) 2007-02-08
JP3692041B2 (en) 2005-09-07
CO5170417A1 (en) 2002-06-27
CA2374247A1 (en) 2000-11-30
MXPA01011920A (en) 2002-05-06
HN2000000051A (en) 2001-02-02
EP1187826A1 (en) 2002-03-20
CA2374247C (en) 2008-01-22
GT200000069A (en) 2001-11-08
TNSN00104A1 (en) 2005-11-10
BR0010746A (en) 2002-02-13
DZ3042A1 (en) 2004-03-27
MA26733A1 (en) 2004-12-20
AU4137400A (en) 2000-12-12
PE20010152A1 (en) 2001-02-08
UY26143A1 (en) 2000-12-29
ATE349440T1 (en) 2007-01-15
JP2003500401A (en) 2003-01-07
WO2000071532A1 (en) 2000-11-30
EP1187826B1 (en) 2006-12-27
US6380214B1 (en) 2002-04-30
ES2276681T3 (en) 2007-07-01
DE60032601T2 (en) 2007-11-15
JP2005008641A (en) 2005-01-13

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