ECSP12012031A - Composición farmacéutica que comprende oligopéptidos - Google Patents

Composición farmacéutica que comprende oligopéptidos

Info

Publication number
ECSP12012031A
ECSP12012031A ECSP12012031A ECSP12012031A EC SP12012031 A ECSP12012031 A EC SP12012031A EC SP12012031 A ECSP12012031 A EC SP12012031A EC SP12012031 A ECSP12012031 A EC SP12012031A
Authority
EC
Ecuador
Prior art keywords
pharmaceutical composition
oligopeptides
includes oligopeptides
lipophilic
amphiphilic
Prior art date
Application number
Other languages
English (en)
Inventor
Marcus Eber
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44145957&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP12012031(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ECSP12012031A publication Critical patent/ECSP12012031A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a una composición farmacéutica de oligopéptidos, con preferencia oligopéptidos cíclicos, en donde dicha composición también comprende uno o varios compuestos lipofílicos y/o anfifílicos, en presencia o ausencia de agua como los ingredientes principales, al uso de los compuestos lipofílicos y/o anfifílicos para preparar composiciones farmacéuticas de dichos oligopéptidos y a métodos de preparación de tal composición farmacéutica.
ECSP12012031 2009-12-10 2012-07-09 Composición farmacéutica que comprende oligopéptidos ECSP12012031A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28531309P 2009-12-10 2009-12-10
US41662810P 2010-11-23 2010-11-23

Publications (1)

Publication Number Publication Date
ECSP12012031A true ECSP12012031A (es) 2012-08-31

Family

ID=44145957

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP12012031 ECSP12012031A (es) 2009-12-10 2012-07-09 Composición farmacéutica que comprende oligopéptidos

Country Status (19)

Country Link
US (1) US9433577B2 (es)
EP (1) EP2509583B1 (es)
JP (1) JP5946770B2 (es)
KR (1) KR20120104316A (es)
CN (1) CN102652015B (es)
AU (1) AU2010330364B2 (es)
BR (1) BR112012012862A2 (es)
CA (1) CA2783732A1 (es)
CL (1) CL2012001310A1 (es)
EA (1) EA022700B1 (es)
EC (1) ECSP12012031A (es)
ES (1) ES2742263T3 (es)
IL (1) IL220097A (es)
MX (1) MX2012006450A (es)
NZ (1) NZ601109A (es)
PE (1) PE20121359A1 (es)
SG (1) SG181487A1 (es)
WO (1) WO2011069629A2 (es)
ZA (1) ZA201205103B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8586545B2 (en) 2009-05-20 2013-11-19 Merck Patent Gmbh Solid materials of {[(2S, 5R,8S,11S)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acid} and methods for obtaining them
PL3023788T3 (pl) 2010-05-14 2020-07-27 The General Hospital Corporation Kompozycje neoantygenów specyficznych wobec nowotworu do zastosowania w leczeniu nowotworów
AU2012266803B2 (en) * 2011-06-09 2017-02-02 Merck Patent Gmbh Treatment of cancers and metastases with suspensions of cilengitide in carrier
WO2015077717A1 (en) 2013-11-25 2015-05-28 The Broad Institute Inc. Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
US11725237B2 (en) 2013-12-05 2023-08-15 The Broad Institute Inc. Polymorphic gene typing and somatic change detection using sequencing data
JP7060324B2 (ja) 2013-12-20 2022-04-26 ザ・ブロード・インスティテュート・インコーポレイテッド ネオ抗原ワクチンによる併用療法
US10975442B2 (en) 2014-12-19 2021-04-13 Massachusetts Institute Of Technology Molecular biomarkers for cancer immunotherapy
US10993997B2 (en) 2014-12-19 2021-05-04 The Broad Institute, Inc. Methods for profiling the t cell repertoire
TW202346325A (zh) 2015-05-20 2023-12-01 美商博德研究所有限公司 共有之gata3相關之腫瘤特異性新抗原
EP3574116A1 (en) 2017-01-24 2019-12-04 The Broad Institute, Inc. Compositions and methods for detecting a mutant variant of a polynucleotide
SG11202000940XA (en) 2017-08-24 2020-02-27 Novo Nordisk As Glp-1 compositions and uses thereof
TW201930340A (zh) 2017-12-18 2019-08-01 美商尼恩醫療公司 新抗原及其用途
CA3165359A1 (en) 2020-02-18 2021-07-22 Dorthe Kot Engelund Glp-1 compositions and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0580778T3 (da) * 1991-04-19 2000-01-31 Lds Technologies Inc Konvertible mikroemulsionsformuleringer
WO1993002665A1 (en) * 1991-07-26 1993-02-18 Smithkline Beecham Corporation W/o microemulsions
DE19534177A1 (de) 1995-09-15 1997-03-20 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
IL128632A (en) * 1996-08-22 2003-03-12 Rtp Pharma Corp Compositions comprising microparticles of water-insoluble substances and method for preparing same
DE19842415A1 (de) 1998-09-16 2000-03-23 Merck Patent Gmbh Pharmazeutische Zubereitung
UA71608C2 (en) 1999-03-11 2004-12-15 Merck Patent Gmbh A method for producing the cyclic pentapeptide
EP1435910B9 (en) * 2001-10-19 2010-02-03 Isotechnika Inc. Novel cyclosporin analog microemulsion preconcentrates
US6656460B2 (en) * 2001-11-01 2003-12-02 Yissum Research Development Method and composition for dry eye treatment
DE10228049A1 (de) * 2002-06-24 2004-01-15 Merck Patent Gmbh Flüssige Zubereitung enthaltend Oligopeptide
AU2004240640A1 (en) 2003-05-19 2004-12-02 Baxter International Inc. Solid particles comprising an anticonvulsant or an immunosuppressive coated with one or more surface modifiers
EP1750671B1 (en) * 2004-06-03 2008-10-15 Bracco Research S.A. Liposomal assembly for therapeutic and/or diagnostic use
US20100204115A1 (en) * 2007-09-11 2010-08-12 Dorian Bevec Use of acetyl- (ala10, 11)-rantes (1-14) and/or calcitonin as anti-angiogenic agents
RU2555357C2 (ru) * 2008-04-08 2015-07-10 Мерк Патент Гмбх Композиции, содержащие циклические пептиды, и способы их применения
US8586545B2 (en) * 2009-05-20 2013-11-19 Merck Patent Gmbh Solid materials of {[(2S, 5R,8S,11S)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acid} and methods for obtaining them

Also Published As

Publication number Publication date
BR112012012862A2 (pt) 2016-08-16
AU2010330364B2 (en) 2016-05-19
WO2011069629A2 (en) 2011-06-16
CN102652015B (zh) 2016-08-03
NZ601109A (en) 2014-06-27
US20120288539A1 (en) 2012-11-15
WO2011069629A3 (en) 2012-03-15
KR20120104316A (ko) 2012-09-20
CN102652015A (zh) 2012-08-29
AU2010330364A1 (en) 2012-07-26
CA2783732A1 (en) 2011-06-16
IL220097A (en) 2017-03-30
US9433577B2 (en) 2016-09-06
EA201200850A1 (ru) 2013-01-30
ZA201205103B (en) 2013-03-27
EA022700B1 (ru) 2016-02-29
MX2012006450A (es) 2012-06-28
ES2742263T3 (es) 2020-02-13
JP2013513556A (ja) 2013-04-22
PE20121359A1 (es) 2012-10-15
CL2012001310A1 (es) 2012-10-12
JP5946770B2 (ja) 2016-07-06
EP2509583B1 (en) 2019-05-15
EP2509583A2 (en) 2012-10-17
SG181487A1 (en) 2012-07-30

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