BR112012012862A2 - composição farmacêutica compreendendo oligopeptídeos - Google Patents
composição farmacêutica compreendendo oligopeptídeosInfo
- Publication number
- BR112012012862A2 BR112012012862A2 BR112012012862A BR112012012862A BR112012012862A2 BR 112012012862 A2 BR112012012862 A2 BR 112012012862A2 BR 112012012862 A BR112012012862 A BR 112012012862A BR 112012012862 A BR112012012862 A BR 112012012862A BR 112012012862 A2 BR112012012862 A2 BR 112012012862A2
- Authority
- BR
- Brazil
- Prior art keywords
- oligopeptides
- pharmaceutical composition
- lipophilic
- composition
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Abstract
composição farmacêutica compreendendo oligopeptídeos. a presente invenção refere-se a uma composição farmacêutica de oligopeptídeos , preferivelmente oligopeptídeos cíclicos, a referida composição compreendendo um ou mais compostos lipofílicos e/ou anfifílicos, na presença ou ausência de água como os ingredientes principais, o uso dos compostos lipofílicos e/ou anfifílicos para a fabricação das composições farmacêuticas dos referidos oligopeptídeos, e métodos de fabricação de da referida composição farmacêutica.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28531309P | 2009-12-10 | 2009-12-10 | |
US41662810P | 2010-11-23 | 2010-11-23 | |
PCT/EP2010/007396 WO2011069629A2 (en) | 2009-12-10 | 2010-12-06 | Pharmaceutical composition comprising oligopeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112012012862A2 true BR112012012862A2 (pt) | 2016-08-16 |
Family
ID=44145957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012012862A BR112012012862A2 (pt) | 2009-12-10 | 2010-12-06 | composição farmacêutica compreendendo oligopeptídeos |
Country Status (19)
Country | Link |
---|---|
US (1) | US9433577B2 (pt) |
EP (1) | EP2509583B1 (pt) |
JP (1) | JP5946770B2 (pt) |
KR (1) | KR20120104316A (pt) |
CN (1) | CN102652015B (pt) |
AU (1) | AU2010330364B2 (pt) |
BR (1) | BR112012012862A2 (pt) |
CA (1) | CA2783732A1 (pt) |
CL (1) | CL2012001310A1 (pt) |
EA (1) | EA022700B1 (pt) |
EC (1) | ECSP12012031A (pt) |
ES (1) | ES2742263T3 (pt) |
IL (1) | IL220097A (pt) |
MX (1) | MX2012006450A (pt) |
NZ (1) | NZ601109A (pt) |
PE (1) | PE20121359A1 (pt) |
SG (1) | SG181487A1 (pt) |
WO (1) | WO2011069629A2 (pt) |
ZA (1) | ZA201205103B (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8586545B2 (en) * | 2009-05-20 | 2013-11-19 | Merck Patent Gmbh | Solid materials of {[(2S, 5R,8S,11S)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acid} and methods for obtaining them |
EP3023788B1 (en) | 2010-05-14 | 2020-02-12 | The General Hospital Corporation | Compositions of tumor specific neoantigens for use in treating tumours |
CA2838573A1 (en) * | 2011-06-09 | 2012-12-13 | Simon Goodman | Treatment of cancers and metastases with suspensions of cilengitide in carrier |
US10801070B2 (en) | 2013-11-25 | 2020-10-13 | The Broad Institute, Inc. | Compositions and methods for diagnosing, evaluating and treating cancer |
WO2015085147A1 (en) | 2013-12-05 | 2015-06-11 | The Broad Institute Inc. | Polymorphic gene typing and somatic change detection using sequencing data |
WO2015095811A2 (en) | 2013-12-20 | 2015-06-25 | The Board Institute Inc. | Combination therapy with neoantigen vaccine |
EP3757211A1 (en) | 2014-12-19 | 2020-12-30 | The Broad Institute, Inc. | Methods for profiling the t-cell-receptor repertoire |
US10975442B2 (en) | 2014-12-19 | 2021-04-13 | Massachusetts Institute Of Technology | Molecular biomarkers for cancer immunotherapy |
MY190974A (en) | 2015-05-20 | 2022-05-25 | Massachusetts Gen Hospital | Shared neoantigens |
WO2018140391A1 (en) | 2017-01-24 | 2018-08-02 | The Broad Institute, Inc. | Compositions and methods for detecting a mutant variant of a polynucleotide |
PL3474820T3 (pl) | 2017-08-24 | 2024-05-13 | Novo Nordisk A/S | Kompozycje glp-1 i ich zastosowania |
WO2019126186A1 (en) | 2017-12-18 | 2019-06-27 | Neon Therapeutics, Inc. | Neoantigens and uses thereof |
CA3165359A1 (en) | 2020-02-18 | 2021-07-22 | Dorthe Kot Engelund | Glp-1 compositions and uses thereof |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2108266C (en) * | 1991-04-19 | 2003-06-03 | Albert J. Owen | Convertible microemulsion formulations |
AU667483B2 (en) * | 1991-07-26 | 1996-03-28 | Smithkline Beecham Corporation | W/O microemulsions |
DE19534177A1 (de) * | 1995-09-15 | 1997-03-20 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
AU719085B2 (en) * | 1996-08-22 | 2000-05-04 | Rtp Pharma Corporation | Processes of preparing or stabilising microparticles |
DE19842415A1 (de) | 1998-09-16 | 2000-03-23 | Merck Patent Gmbh | Pharmazeutische Zubereitung |
UA71608C2 (en) | 1999-03-11 | 2004-12-15 | Merck Patent Gmbh | A method for producing the cyclic pentapeptide |
MY145753A (en) * | 2001-10-19 | 2012-03-30 | Isotechnika Inc | Novel cyclosporin analog formulations |
US6656460B2 (en) * | 2001-11-01 | 2003-12-02 | Yissum Research Development | Method and composition for dry eye treatment |
DE10228049A1 (de) * | 2002-06-24 | 2004-01-15 | Merck Patent Gmbh | Flüssige Zubereitung enthaltend Oligopeptide |
MXPA05012467A (es) | 2003-05-19 | 2006-02-22 | Baxter Int | Particulas solidas que comprenden un anticonvulsivo o un inmunosupresor revestido con uno o mas modificadores de superficie. |
US7749485B2 (en) * | 2004-06-03 | 2010-07-06 | Bracco Research S.A. | Liposomal assembly for therapeutic and/or diagnostic use |
WO2009040071A2 (en) * | 2007-09-11 | 2009-04-02 | Mondobiotech Laboratories Ag | Use of a peptide as a therapeutic agent |
US20110027209A1 (en) * | 2008-04-08 | 2011-02-03 | Merck Patent Gesellschaft | Compositions Containing Cyclic Peptides And Methods Of Use |
US8586545B2 (en) * | 2009-05-20 | 2013-11-19 | Merck Patent Gmbh | Solid materials of {[(2S, 5R,8S,11S)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acid} and methods for obtaining them |
-
2010
- 2010-12-06 SG SG2012040754A patent/SG181487A1/en unknown
- 2010-12-06 NZ NZ601109A patent/NZ601109A/en not_active IP Right Cessation
- 2010-12-06 EP EP10787035.4A patent/EP2509583B1/en not_active Not-in-force
- 2010-12-06 CA CA2783732A patent/CA2783732A1/en not_active Abandoned
- 2010-12-06 ES ES10787035T patent/ES2742263T3/es active Active
- 2010-12-06 PE PE2012000796A patent/PE20121359A1/es not_active Application Discontinuation
- 2010-12-06 US US13/515,244 patent/US9433577B2/en active Active
- 2010-12-06 MX MX2012006450A patent/MX2012006450A/es not_active Application Discontinuation
- 2010-12-06 AU AU2010330364A patent/AU2010330364B2/en not_active Ceased
- 2010-12-06 BR BR112012012862A patent/BR112012012862A2/pt not_active IP Right Cessation
- 2010-12-06 WO PCT/EP2010/007396 patent/WO2011069629A2/en active Application Filing
- 2010-12-06 JP JP2012542389A patent/JP5946770B2/ja not_active Expired - Fee Related
- 2010-12-06 KR KR1020127017966A patent/KR20120104316A/ko not_active Application Discontinuation
- 2010-12-06 CN CN201080055767.4A patent/CN102652015B/zh not_active Expired - Fee Related
- 2010-12-06 EA EA201200850A patent/EA022700B1/ru not_active IP Right Cessation
-
2012
- 2012-05-18 CL CL2012001310A patent/CL2012001310A1/es unknown
- 2012-05-31 IL IL220097A patent/IL220097A/en active IP Right Grant
- 2012-07-09 ZA ZA2012/05103A patent/ZA201205103B/en unknown
- 2012-07-09 EC ECSP12012031 patent/ECSP12012031A/es unknown
Also Published As
Publication number | Publication date |
---|---|
JP2013513556A (ja) | 2013-04-22 |
ECSP12012031A (es) | 2012-08-31 |
AU2010330364A1 (en) | 2012-07-26 |
MX2012006450A (es) | 2012-06-28 |
CN102652015A (zh) | 2012-08-29 |
CL2012001310A1 (es) | 2012-10-12 |
WO2011069629A2 (en) | 2011-06-16 |
ES2742263T3 (es) | 2020-02-13 |
ZA201205103B (en) | 2013-03-27 |
US9433577B2 (en) | 2016-09-06 |
US20120288539A1 (en) | 2012-11-15 |
NZ601109A (en) | 2014-06-27 |
PE20121359A1 (es) | 2012-10-15 |
EP2509583A2 (en) | 2012-10-17 |
JP5946770B2 (ja) | 2016-07-06 |
EA022700B1 (ru) | 2016-02-29 |
AU2010330364B2 (en) | 2016-05-19 |
SG181487A1 (en) | 2012-07-30 |
CA2783732A1 (en) | 2011-06-16 |
IL220097A (en) | 2017-03-30 |
WO2011069629A3 (en) | 2012-03-15 |
KR20120104316A (ko) | 2012-09-20 |
EA201200850A1 (ru) | 2013-01-30 |
EP2509583B1 (en) | 2019-05-15 |
CN102652015B (zh) | 2016-08-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |