ECSP11011174A - Derivados de sulfonamida como agentes inductores de apoptesis con selectividad por bcl-2 para el tratamiento de cáncer y enfermedades inmunes - Google Patents

Derivados de sulfonamida como agentes inductores de apoptesis con selectividad por bcl-2 para el tratamiento de cáncer y enfermedades inmunes

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Publication number
ECSP11011174A
ECSP11011174A EC2011011174A ECSP11011174A ECSP11011174A EC SP11011174 A ECSP11011174 A EC SP11011174A EC 2011011174 A EC2011011174 A EC 2011011174A EC SP11011174 A ECSP11011174 A EC SP11011174A EC SP11011174 A ECSP11011174 A EC SP11011174A
Authority
EC
Ecuador
Prior art keywords
bcl
apoptesis
selectivity
cancer treatment
immune diseases
Prior art date
Application number
EC2011011174A
Other languages
English (en)
Inventor
George Andrew Doherty
Lisa A Hasvold
Gerard M Sullivan
Gary Wang
Steven W Elmore
Andrew J Souers
Milan Bruncko
Xiaohong Song
Xilu Wang
Le Wang
Aaron R Kunzer
Cheol-Min Park
Michael D Wendt
Zhi-Fu Tao
Hong Ding
Laura Hexamer
William J Mcclellan
Chang H Park
Andrew M Petros
Robert A Mantel
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41786218&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP11011174(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of ECSP11011174A publication Critical patent/ECSP11011174A/es

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    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Abstract

Compuestos que inhiben la actividad de las proteínas anti-apoptóticas Bcl-2 o Bcl-XL, composiciones que contienen dichos compuestos y métodos para tratar enfermedades durante las cuales se expresa la proteína anti-apoptótica Bcl-2.
EC2011011174A 2008-12-05 2011-07-04 Derivados de sulfonamida como agentes inductores de apoptesis con selectividad por bcl-2 para el tratamiento de cáncer y enfermedades inmunes ECSP11011174A (es)

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