ECSP10010589A - Farmaco contra el cancer de higado - Google Patents

Farmaco contra el cancer de higado

Info

Publication number
ECSP10010589A
ECSP10010589A EC2010010589A ECSP10010589A ECSP10010589A EC SP10010589 A ECSP10010589 A EC SP10010589A EC 2010010589 A EC2010010589 A EC 2010010589A EC SP10010589 A ECSP10010589 A EC SP10010589A EC SP10010589 A ECSP10010589 A EC SP10010589A
Authority
EC
Ecuador
Prior art keywords
chemotherapeutic agent
liver cancer
antiglipican
antibody
pharmaceutical composition
Prior art date
Application number
EC2010010589A
Other languages
English (en)
Inventor
Masamichi Sugimoto
Takahiro Ishiguro
Yasuko Kinoshita
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41135076&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP10010589(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/JP2008/002690 external-priority patent/WO2009041062A1/ja
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of ECSP10010589A publication Critical patent/ECSP10010589A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se proporcionan una composicion farmaceutica novedosa para tratar o prevenir carcinoma hepatocelular y un metodo de tratamiento. Se obtiene una composicion farmaceutica para tratar o prevenir cancer de higado al combinar un agente quimioterapeutico con un anticuerpo 3 antiglipicano. Tambien se describe una composicion farmaceutica para tratar o prevenir cancer de higado que comprende como un ingrediente activo un anticuerpo 3 antiglipicano para uso en combinacion con un agente quimioterapeutico, o que comprende como un ingrediente activo un agente quimioterapeutico para uso en combinacion con un anticuerpo 3 antiglipicano. La utilizacion del agente quimioterapeutico y el anticuerpo 3 antiglipicano en combinacion proporciona mejores efectos terapeuticos que utilizando solo el agente quimioterapeutico, y mitiga los efectos colaterales que surgen del tratamiento contra el cancer de higado tratamiento con el agente quimioterapeutico.
EC2010010589A 2008-04-04 2010-11-04 Farmaco contra el cancer de higado ECSP10010589A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008098309 2008-04-04
PCT/JP2008/002690 WO2009041062A1 (ja) 2007-09-28 2008-09-26 血漿中動態が改善されたグリピカン３抗体

Publications (1)

Publication Number Publication Date
ECSP10010589A true ECSP10010589A (es) 2010-12-30

Family

ID=41135076

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2010010589A ECSP10010589A (es) 2008-04-04 2010-11-04 Farmaco contra el cancer de higado

Country Status (24)

Country Link
US (1) US20110104157A1 (es)
EP (1) EP2275135A4 (es)
JP (2) JP5306327B2 (es)
KR (1) KR101612139B1 (es)
CN (1) CN102046200B (es)
AR (1) AR071003A1 (es)
AU (1) AU2009233301B2 (es)
BR (1) BRPI0911147A2 (es)
CA (1) CA2720359A1 (es)
CL (1) CL2009000647A1 (es)
CO (1) CO6300964A2 (es)
CR (1) CR11769A (es)
EC (1) ECSP10010589A (es)
HK (1) HK1151734A1 (es)
IL (1) IL208451A0 (es)
MA (1) MA32360B1 (es)
MX (1) MX2010010954A (es)
NZ (1) NZ588913A (es)
PE (1) PE20091655A1 (es)
RU (1) RU2523897C2 (es)
SG (1) SG189754A1 (es)
TW (1) TWI468175B (es)
UA (1) UA103614C2 (es)
WO (1) WO2009122667A1 (es)

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SG11201407972RA (en) * 2012-06-01 2015-01-29 Us Health High-affinity monoclonal antibodies to glypican-3 and use thereof
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Also Published As

Publication number Publication date
RU2010145177A (ru) 2012-05-20
CA2720359A1 (en) 2009-10-08
CO6300964A2 (es) 2011-07-21
JP5306327B2 (ja) 2013-10-02
JP5506654B2 (ja) 2014-05-28
PE20091655A1 (es) 2009-11-04
US20110104157A1 (en) 2011-05-05
UA103614C2 (uk) 2013-11-11
SG189754A1 (en) 2013-05-31
AU2009233301B2 (en) 2014-01-23
CN102046200A (zh) 2011-05-04
CN102046200B (zh) 2015-03-25
HK1151734A1 (en) 2012-02-10
AU2009233301A1 (en) 2009-10-08
JPWO2009122667A1 (ja) 2011-07-28
WO2009122667A1 (ja) 2009-10-08
KR101612139B1 (ko) 2016-04-12
TWI468175B (zh) 2015-01-11
KR20100132060A (ko) 2010-12-16
EP2275135A4 (en) 2013-03-06
TW200950804A (en) 2009-12-16
MA32360B1 (fr) 2011-06-01
RU2523897C2 (ru) 2014-07-27
AR071003A1 (es) 2010-05-19
CL2009000647A1 (es) 2010-06-04
IL208451A0 (en) 2010-12-30
NZ588913A (en) 2012-10-26
JP2011068682A (ja) 2011-04-07
CR11769A (es) 2011-03-30
BRPI0911147A2 (pt) 2019-09-24
MX2010010954A (es) 2011-03-24
EP2275135A1 (en) 2011-01-19

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