EA201890727A1 - Модуляторы взаимодействия сестрина-gator2 и их применение - Google Patents

Модуляторы взаимодействия сестрина-gator2 и их применение

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Publication number
EA201890727A1
EA201890727A1 EA201890727A EA201890727A EA201890727A1 EA 201890727 A1 EA201890727 A1 EA 201890727A1 EA 201890727 A EA201890727 A EA 201890727A EA 201890727 A EA201890727 A EA 201890727A EA 201890727 A1 EA201890727 A1 EA 201890727A1
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EA
Eurasian Patent Office
Prior art keywords
sistrin
gator2
models
interaction
application
Prior art date
Application number
EA201890727A
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English (en)
Other versions
EA039229B1 (ru
Inventor
Кристина Мишель Фетальверо
Сридхар Нарайян
Дэвид Джон О'Нил
Эддин Сайях
Шомит Сенгупта
Original Assignee
Навитор Фармасьютикалз, Инк.
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Publication date
Application filed by Навитор Фармасьютикалз, Инк. filed Critical Навитор Фармасьютикалз, Инк.
Priority claimed from PCT/US2016/058188 external-priority patent/WO2017070518A1/en
Publication of EA201890727A1 publication Critical patent/EA201890727A1/ru
Publication of EA039229B1 publication Critical patent/EA039229B1/ru

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    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
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    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
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Abstract

В настоящем изобретении предложены соединения, содержащие их композиции и способы их применения.
EA201890727A 2016-05-13 2016-10-21 Модуляторы взаимодействия сестрина-gator2 и их применение EA039229B1 (ru)

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