EA201590862A1 - Фармацевтические композиции - Google Patents

Фармацевтические композиции

Info

Publication number
EA201590862A1
EA201590862A1 EA201590862A EA201590862A EA201590862A1 EA 201590862 A1 EA201590862 A1 EA 201590862A1 EA 201590862 A EA201590862 A EA 201590862A EA 201590862 A EA201590862 A EA 201590862A EA 201590862 A1 EA201590862 A1 EA 201590862A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutical compositions
hiv
infections
prevention
useful
Prior art date
Application number
EA201590862A
Other languages
English (en)
Inventor
Шеньшень Цай
Брайан Элвин Джонс
Эндрю Спалтенштейн
Original Assignee
ГЛАКСОСМИТКЛАЙН ЭлЭлСи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ГЛАКСОСМИТКЛАЙН ЭлЭлСи filed Critical ГЛАКСОСМИТКЛАЙН ЭлЭлСи
Publication of EA201590862A1 publication Critical patent/EA201590862A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Настоящее изобретение относится к фармацевтическим композициям производных бетулина или их фармацевтически приемлемых солей длительного действия, полезным в лечении или предупреждении инфекций вирусом иммунодефицита человека (ВИЧ).
EA201590862A 2012-12-14 2013-12-14 Фармацевтические композиции EA201590862A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261737177P 2012-12-14 2012-12-14
PCT/US2013/075196 WO2014093941A1 (en) 2012-12-14 2013-12-14 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
EA201590862A1 true EA201590862A1 (ru) 2016-05-31

Family

ID=50935020

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201590862A EA201590862A1 (ru) 2012-12-14 2013-12-14 Фармацевтические композиции

Country Status (20)

Country Link
US (2) US9795619B2 (ru)
EP (1) EP2931285A4 (ru)
JP (1) JP2016503030A (ru)
KR (1) KR20150093819A (ru)
CN (1) CN104902905A (ru)
AU (1) AU2013358897B2 (ru)
BR (1) BR112015013695A2 (ru)
CA (1) CA2893959A1 (ru)
CL (1) CL2015001660A1 (ru)
CR (1) CR20150313A (ru)
EA (1) EA201590862A1 (ru)
HK (1) HK1209638A1 (ru)
IL (1) IL238807A0 (ru)
MA (1) MA38182A1 (ru)
MX (1) MX2015007563A (ru)
PE (1) PE20151326A1 (ru)
PH (1) PH12015501156A1 (ru)
SG (2) SG11201503807TA (ru)
WO (1) WO2014093941A1 (ru)
ZA (1) ZA201503594B (ru)

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US9637516B2 (en) 2012-12-31 2017-05-02 Hetero Research Foundation Betulinic acid proline derivatives as HIV inhibitors
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HUE037347T2 (hu) 2013-07-12 2018-08-28 Gilead Sciences Inc Policiklusos karmaboilpiridon vegyületek és alkalmazásuk HIV fertõzések kezelésére
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
NO2717902T3 (ru) 2014-06-20 2018-06-23
TWI677489B (zh) 2014-06-20 2019-11-21 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
US20170129916A1 (en) 2014-06-26 2017-05-11 Hetero Research Foundation Novel betulinic proline imidazole derivatives as hiv inhibitors
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TWI695003B (zh) 2014-12-23 2020-06-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
MA40886B1 (fr) 2015-02-09 2020-03-31 Hetero Research Foundation Nouveau triterpénone en c-3 avec des dérivés d'amide inverse en c-28 en tant qu'inhibiteurs du vih
WO2016147099A2 (en) 2015-03-16 2016-09-22 Hetero Research Foundation C-3 novel triterpenone with c-28 amide derivatives as hiv inhibitors
PL3277691T3 (pl) 2015-04-02 2019-07-31 Gilead Sciences, Inc. Policykliczne związki karbamoilopirydonowe i ich zastosowanie farmaceutyczne
WO2018042331A1 (en) * 2016-08-31 2018-03-08 Glaxosmithkline Intellectual Property (No.2) Limited Combinations and uses and treatments thereof
WO2018042332A1 (en) * 2016-08-31 2018-03-08 Glaxosmithkline Intellectual Property (No.2) Limited Combinations and uses and treatments thereof
US11564921B2 (en) 2017-07-21 2023-01-31 Viiv Healthcare Company Regimens for treating HIV infections and AIDS

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MX2015007563A (es) * 2012-12-14 2015-10-14 Glaxosmithkline Llc Composiciones farmaceuticas.
AU2015323321A1 (en) 2014-09-26 2017-04-13 Glaxosmithkline Intellectual Property (No.2) Limited Long acting pharmaceutical compositions

Also Published As

Publication number Publication date
WO2014093941A1 (en) 2014-06-19
US20180042944A1 (en) 2018-02-15
CN104902905A (zh) 2015-09-09
SG10201704467SA (en) 2017-06-29
MA38182A1 (fr) 2018-04-30
JP2016503030A (ja) 2016-02-01
EP2931285A1 (en) 2015-10-21
PH12015501156A1 (en) 2015-08-10
AU2013358897B2 (en) 2017-01-05
US20150313917A1 (en) 2015-11-05
AU2013358897A1 (en) 2015-07-02
CL2015001660A1 (es) 2015-10-02
ZA201503594B (en) 2018-11-28
KR20150093819A (ko) 2015-08-18
BR112015013695A2 (pt) 2017-07-11
HK1209638A1 (en) 2016-04-08
US9795619B2 (en) 2017-10-24
PE20151326A1 (es) 2015-10-12
CR20150313A (es) 2015-10-19
EP2931285A4 (en) 2016-06-01
SG11201503807TA (en) 2015-06-29
MX2015007563A (es) 2015-10-14
CA2893959A1 (en) 2014-06-19
IL238807A0 (en) 2015-06-30

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