EA201400882A1 - Способ стереоселективного синтеза 9-гидрокси-5-оксо-1,4-диазаспиро[5.5]ундеканов, содержащих защитные группы в 1,4-положениях - Google Patents
Способ стереоселективного синтеза 9-гидрокси-5-оксо-1,4-диазаспиро[5.5]ундеканов, содержащих защитные группы в 1,4-положенияхInfo
- Publication number
- EA201400882A1 EA201400882A1 EA201400882A EA201400882A EA201400882A1 EA 201400882 A1 EA201400882 A1 EA 201400882A1 EA 201400882 A EA201400882 A EA 201400882A EA 201400882 A EA201400882 A EA 201400882A EA 201400882 A1 EA201400882 A1 EA 201400882A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- stereoelective
- undecanes
- diazaspiro
- provisions
- oxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
Abstract
В заявке описан способ стереоселективного получения соединения формулы (5) необязательно в форме его таутомеров.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12154688 | 2012-02-09 | ||
PCT/EP2013/052287 WO2013117568A1 (de) | 2012-02-09 | 2013-02-06 | Verfahren zur stereoselektiven synthese von 1,4-geschützten 9-hydroxy-5-oxo-1,4-diaza-spiro [5.5] undecane |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201400882A1 true EA201400882A1 (ru) | 2015-01-30 |
Family
ID=47678813
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201400882A EA201400882A1 (ru) | 2012-02-09 | 2013-02-06 | Способ стереоселективного синтеза 9-гидрокси-5-оксо-1,4-диазаспиро[5.5]ундеканов, содержащих защитные группы в 1,4-положениях |
Country Status (14)
Country | Link |
---|---|
US (1) | US8629146B2 (ru) |
EP (1) | EP2812317B1 (ru) |
JP (1) | JP6105631B2 (ru) |
KR (1) | KR20140128318A (ru) |
CN (1) | CN104080775A (ru) |
AU (1) | AU2013218119A1 (ru) |
BR (1) | BR112014019196A8 (ru) |
CA (1) | CA2862520A1 (ru) |
CL (1) | CL2014001823A1 (ru) |
EA (1) | EA201400882A1 (ru) |
IL (1) | IL233370A (ru) |
MX (1) | MX2014009033A (ru) |
PH (1) | PH12014501760B1 (ru) |
WO (1) | WO2013117568A1 (ru) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2289881A1 (de) * | 2009-08-06 | 2011-03-02 | Boehringer Ingelheim International GmbH | Verfahren zur stereoselektiven Synthese bicyclischer Heterocyclen |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4575507A (en) * | 1985-05-29 | 1986-03-11 | Pfizer Inc. | Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use |
US6924285B2 (en) | 2002-03-30 | 2005-08-02 | Boehringer Ingelheim Pharma Gmbh & Co. | Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them |
EA009300B1 (ru) | 2002-03-30 | 2007-12-28 | Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг | 4-(n-фениламино)хиназолины/-хинолины в качестве ингибиторов тирозинкиназы |
BRPI0619603A2 (pt) | 2005-12-12 | 2011-10-11 | Boehringer Ingelheim Int | heterociclos bicìclicos, sais fisiologicamante compatìveis, medicamentos que contêm esses compostos, bem como uso e processos para produção dos heterociclos bicìclicos |
WO2009098061A1 (de) | 2008-02-07 | 2009-08-13 | Boehringer Ingelheim International Gmbh | Spirocyclische heterocyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung |
EP2289881A1 (de) | 2009-08-06 | 2011-03-02 | Boehringer Ingelheim International GmbH | Verfahren zur stereoselektiven Synthese bicyclischer Heterocyclen |
EA023573B1 (ru) | 2011-02-01 | 2016-06-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Дималеат 9-[4-(3-хлор-2-фторфениламино)-7-метоксихиназолин-6-илокси]-1,4-диазаспиро[5.5]ундекан-5-она, его применение в качестве лекарственного средства и его получение |
-
2013
- 2013-02-06 JP JP2014556029A patent/JP6105631B2/ja active Active
- 2013-02-06 EA EA201400882A patent/EA201400882A1/ru unknown
- 2013-02-06 CA CA2862520A patent/CA2862520A1/en not_active Abandoned
- 2013-02-06 KR KR1020147021922A patent/KR20140128318A/ko not_active Application Discontinuation
- 2013-02-06 BR BR112014019196A patent/BR112014019196A8/pt not_active IP Right Cessation
- 2013-02-06 EP EP13703045.8A patent/EP2812317B1/de active Active
- 2013-02-06 WO PCT/EP2013/052287 patent/WO2013117568A1/de active Application Filing
- 2013-02-06 MX MX2014009033A patent/MX2014009033A/es not_active Application Discontinuation
- 2013-02-06 AU AU2013218119A patent/AU2013218119A1/en not_active Abandoned
- 2013-02-06 CN CN201380006918.0A patent/CN104080775A/zh active Pending
- 2013-02-07 US US13/761,211 patent/US8629146B2/en active Active
-
2014
- 2014-06-25 IL IL233370A patent/IL233370A/en not_active IP Right Cessation
- 2014-07-09 CL CL2014001823A patent/CL2014001823A1/es unknown
- 2014-08-05 PH PH12014501760A patent/PH12014501760B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
MX2014009033A (es) | 2014-10-17 |
KR20140128318A (ko) | 2014-11-05 |
BR112014019196A8 (pt) | 2017-07-11 |
EP2812317B1 (de) | 2016-02-03 |
CA2862520A1 (en) | 2013-08-15 |
WO2013117568A1 (de) | 2013-08-15 |
IL233370A (en) | 2015-04-30 |
PH12014501760A1 (en) | 2014-11-10 |
US20130211081A1 (en) | 2013-08-15 |
IL233370A0 (en) | 2014-08-31 |
PH12014501760B1 (en) | 2014-11-10 |
JP2015506966A (ja) | 2015-03-05 |
US8629146B2 (en) | 2014-01-14 |
JP6105631B2 (ja) | 2017-03-29 |
AU2013218119A1 (en) | 2014-07-17 |
BR112014019196A2 (ru) | 2017-06-20 |
EP2812317A1 (de) | 2014-12-17 |
CL2014001823A1 (es) | 2015-03-06 |
CN104080775A (zh) | 2014-10-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PH12014502169A1 (en) | N-cyclylamides as nematicides | |
AU2013291345B2 (en) | Composition for controlling plant disease and application therefor | |
PH12016500676A1 (en) | Pyrimidine fgfr4 inhibitors | |
PH12015501993A1 (en) | Pyrazole-amide compound and medicinal uses therefor | |
JO3433B1 (ar) | حلقة كاربوكسامايد ذات أربع أعضاء للاستخدام كمبيدات النيماتودا | |
MY163187A (en) | Novel imidazo-oxazine compound or salt thereof | |
MX341456B (es) | Amino-quinolinas como inhibidores de cinasa. | |
RS54730B1 (sr) | Inhibitori beta sekretaze | |
CR20130539A (es) | Triazolopiridinas | |
UA118666C2 (uk) | Похідні піразолу | |
IN2015DN01061A (ru) | ||
UY33976A (es) | Derivados de pirazolo-pirimidina. | |
UA110128C2 (ru) | Индолкарбоксамиды и бензимидазолкарбоксамиды как инсектициды и акарициды | |
UA111333C2 (uk) | Спосіб одержання l-аргінінової солі периндроприлу | |
PH12016500461A1 (en) | Polyethylene glycol-containing composition | |
GEP201706626B (en) | Synthesis of (s)-nifuratel | |
IN2014DN10669A (ru) | ||
CY1121116T1 (el) | Νεα μεθοδος για την συνθεση αγομελατινης | |
PH12015501146A1 (en) | Hydantoin derivative | |
BR112012025490A2 (pt) | ''método para produção de 1,5 oebtanodiamina'' | |
GB2523674A (en) | Compounds as inhibitor of DNA double-strand break repair, methods and applications thereof | |
MX2016000487A (es) | Piridina-2-carboxamidas como nematicidas. | |
EA201400882A1 (ru) | Способ стереоселективного синтеза 9-гидрокси-5-оксо-1,4-диазаспиро[5.5]ундеканов, содержащих защитные группы в 1,4-положениях | |
CO7200259A2 (es) | Nuevos derivados de piridina | |
BR112017005618A2 (pt) | ?sal de éster metílico de fenilglicina?. |