EA201001297A1 - METHOD FOR DIAGNOSTICS OF HUMAN MELANOMA ON THE BASIS OF DETERMINING THE EXPRESSION LEVEL PHF10 GENE, DIAGNOSTIC KIT - Google Patents
METHOD FOR DIAGNOSTICS OF HUMAN MELANOMA ON THE BASIS OF DETERMINING THE EXPRESSION LEVEL PHF10 GENE, DIAGNOSTIC KITInfo
- Publication number
- EA201001297A1 EA201001297A1 EA201001297A EA201001297A EA201001297A1 EA 201001297 A1 EA201001297 A1 EA 201001297A1 EA 201001297 A EA201001297 A EA 201001297A EA 201001297 A EA201001297 A EA 201001297A EA 201001297 A1 EA201001297 A1 EA 201001297A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- phf10
- gene
- human melanoma
- basis
- determining
- Prior art date
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Настоящее изобретение относится к способу диагностики меланомы человека на основании определения уровня экспрессии гена PHF10 в клетках пациента, причем сниженный уровень экспрессии гена PHF10 в клетках образца морфологически опухолевой ткани по сравнению с таковым в клетках образца морфологически нормальной ткани свидетельствует о наличии у пациента меланомы. Также раскрыт набор для проведения диагностики меланомы человека, содержащий по меньшей мере две пары праймеров, специфичных к гену PHF10, и по меньшей мере одну пару контрольных праймеров.The present invention relates to a method for diagnosing human melanoma on the basis of determining the level of expression of the PHF10 gene in a patient’s cells, with a reduced level of expression of the PHF10 gene in a sample of morphologically tumor tissue compared with that of a morphologically normal tissue in a sample of the patient. Also disclosed is a kit for diagnosing human melanoma, containing at least two pairs of primers specific for the PHF10 gene, and at least one pair of control primers.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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EA201001297A EA019599B1 (en) | 2010-09-13 | 2010-09-13 | Method for diagnosis of melanoma of a human based on determination of phf 10 gene expression level, diagnostic kit |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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EA201001297A EA019599B1 (en) | 2010-09-13 | 2010-09-13 | Method for diagnosis of melanoma of a human based on determination of phf 10 gene expression level, diagnostic kit |
Publications (2)
Publication Number | Publication Date |
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EA201001297A1 true EA201001297A1 (en) | 2012-03-30 |
EA019599B1 EA019599B1 (en) | 2014-04-30 |
Family
ID=45908238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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EA201001297A EA019599B1 (en) | 2010-09-13 | 2010-09-13 | Method for diagnosis of melanoma of a human based on determination of phf 10 gene expression level, diagnostic kit |
Country Status (1)
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EA (1) | EA019599B1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3127759A1 (en) * | 2019-01-24 | 2020-07-30 | Council Of Scientific And Industrial Research | Kit for detecting melanoma |
RU2715678C1 (en) * | 2019-10-31 | 2020-03-02 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр глазных болезней имени Гельмгольца" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ГБ им. Гельмгольца" Минздрава России) | Method for differential diagnosis of initial melanoma of ciliochoroidal localization and chronic iridocyclitis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
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GB0504302D0 (en) * | 2005-03-02 | 2005-04-06 | Univ Dublin | Markers for melanoma |
EP2177615A1 (en) * | 2008-10-10 | 2010-04-21 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Method for a genome wide identification of expression regulatory sequences and use of genes and molecules derived thereof for the diagnosis and therapy of metabolic and/or tumorous diseases |
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2010
- 2010-09-13 EA EA201001297A patent/EA019599B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
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EA019599B1 (en) | 2014-04-30 |
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Legal Events
Date | Code | Title | Description |
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MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM |
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MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): RU |