EA201001085A1 - Фармацевтические композиции, содержащие гранулы очищенной микробной липазы, и способы предупреждения или лечения пищеварительных нарушений - Google Patents
Фармацевтические композиции, содержащие гранулы очищенной микробной липазы, и способы предупреждения или лечения пищеварительных нарушенийInfo
- Publication number
- EA201001085A1 EA201001085A1 EA201001085A EA201001085A EA201001085A1 EA 201001085 A1 EA201001085 A1 EA 201001085A1 EA 201001085 A EA201001085 A EA 201001085A EA 201001085 A EA201001085 A EA 201001085A EA 201001085 A1 EA201001085 A1 EA 201001085A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- pharmaceutical compositions
- prevention
- treatment
- compositions containing
- disabilities
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01003—Triacylglycerol lipase (3.1.1.3)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
В заявке описаны фармацевтические композиции, содержащие гранулы, которые содержат по меньшей мере одну созданную методом рекомбинации очищенную микробную липазу, применение указанных фармацевтических композиций для приготовления лекарственного средства, предназначенного для предупреждения или лечения определенных заболеваний или нарушений типа эндокринной панкреатической недостаточности, и способ изготовления указанных фармацевтических композиций.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1883408P | 2008-01-03 | 2008-01-03 | |
EP08150018 | 2008-01-03 | ||
PCT/EP2009/050010 WO2009083607A1 (en) | 2008-01-03 | 2009-01-02 | Pharmaceutical compositions comprising granules of purified microbial lipase and methods for preventing or treating digestive disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201001085A1 true EA201001085A1 (ru) | 2011-02-28 |
Family
ID=39708910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201001085A EA201001085A1 (ru) | 2008-01-03 | 2009-01-02 | Фармацевтические композиции, содержащие гранулы очищенной микробной липазы, и способы предупреждения или лечения пищеварительных нарушений |
Country Status (11)
Country | Link |
---|---|
US (1) | US20110008423A1 (ru) |
EP (1) | EP2237771A1 (ru) |
JP (1) | JP2011508755A (ru) |
KR (1) | KR20100101106A (ru) |
CN (1) | CN101951893A (ru) |
AU (1) | AU2009203123A1 (ru) |
BR (1) | BRPI0906439A2 (ru) |
CA (1) | CA2711187A1 (ru) |
EA (1) | EA201001085A1 (ru) |
MX (1) | MX2010007242A (ru) |
WO (1) | WO2009083607A1 (ru) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2712877C2 (ru) * | 2013-05-14 | 2020-01-31 | Новозимс А/С | Моющие композиции |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101968457B1 (ko) | 2010-10-01 | 2019-04-11 | 앨러간 파마슈티컬스 인터내셔널 리미티드 | 장용 코팅된 저 강도 췌장 리파제 제제 |
CN104080908B (zh) * | 2012-02-03 | 2018-02-06 | 诺维信公司 | 脂肪酶变体以及编码它们的多核苷酸 |
JP2016537387A (ja) | 2013-08-09 | 2016-12-01 | アラガン ファーマシューティカルズ インターナショナル リミテッド | 経腸投与に適した消化酵素組成物 |
DE102017104482A1 (de) * | 2017-03-03 | 2018-09-06 | Nordmark Arzneimittel Gmbh & Co. Kg | Pharmazeutische Zusammensetzung umfassend Pankreatin und einen lipasehaltigen Überzug |
DE102017104501A1 (de) | 2017-03-03 | 2018-09-06 | Nordmark Arzneimittel Gmbh & Co. Kg | Pharmazeutische Zusammensetzung umfassend einen Träger und einen Überzug enthaltend wenigstens eine Lipase |
EP3459528B1 (en) | 2017-09-20 | 2022-11-23 | Tillotts Pharma Ag | Preparation of solid dosage forms comprising antibodies by solution/suspension layering |
CA3241218A1 (en) * | 2021-12-16 | 2023-06-22 | Dinesh SRINIVASAN | Stable lipase formulations and methods thereof |
WO2023225459A2 (en) | 2022-05-14 | 2023-11-23 | Novozymes A/S | Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1509866A (en) * | 1975-06-10 | 1978-05-04 | Johnson & Johnson | Enteric coated digestive enzyme compositions |
GB1590432A (en) * | 1976-07-07 | 1981-06-03 | Novo Industri As | Process for the production of an enzyme granulate and the enzyme granuate thus produced |
US4447412A (en) * | 1983-02-01 | 1984-05-08 | Bilton Gerald L | Enzyme-containing digestive aid compostions |
US4689297A (en) * | 1985-03-05 | 1987-08-25 | Miles Laboratories, Inc. | Dust free particulate enzyme formulation |
DK173590D0 (da) * | 1990-06-06 | 1990-07-19 | Novo Nordisk As | Rekombinante terapeutiske lipaser |
US5869438A (en) * | 1990-09-13 | 1999-02-09 | Novo Nordisk A/S | Lipase variants |
US5324649A (en) * | 1991-10-07 | 1994-06-28 | Genencor International, Inc. | Enzyme-containing granules coated with hydrolyzed polyvinyl alcohol or copolymer thereof |
AU677166B2 (en) * | 1991-10-07 | 1997-04-17 | Genencor International, Inc. | Coated enzyme containing granule |
US5879920A (en) * | 1991-10-07 | 1999-03-09 | Genencor International, Inc. | Coated enzyme-containing granule |
DE4322229A1 (de) * | 1993-07-05 | 1995-01-12 | Cognis Bio Umwelt | Umhüllte Enzymzubereitung für Wasch- und Reinigungsmittel |
DE4344215A1 (de) * | 1993-12-23 | 1995-06-29 | Cognis Bio Umwelt | Silberkorrosionsschutzmittelhaltige Enzymzubereitung |
DE69737828T2 (de) * | 1996-04-29 | 2008-03-06 | Novozymes A/S | Flüssige, nichtwässrige enzyme enthaltende zusammensetzungen |
US6268329B1 (en) * | 1998-06-30 | 2001-07-31 | Nouozymes A/S | Enzyme containing granule |
AR032392A1 (es) * | 2001-01-19 | 2003-11-05 | Solvay Pharm Gmbh | Mezcla de enzimas, preparado farmaceutico y utilizacion de dicho preparado. |
AU2006261442A1 (en) * | 2005-06-24 | 2006-12-28 | Novozymes A/S | Lipases for pharmaceutical use |
ATE418329T1 (de) * | 2005-08-15 | 2009-01-15 | Solvay Pharm Gmbh | Pankreatin-mikropellets geeignet für magensaftresistente überzüge |
-
2009
- 2009-01-02 US US12/811,410 patent/US20110008423A1/en not_active Abandoned
- 2009-01-02 JP JP2010541061A patent/JP2011508755A/ja active Pending
- 2009-01-02 BR BRPI0906439A patent/BRPI0906439A2/pt not_active IP Right Cessation
- 2009-01-02 CN CN2009801016377A patent/CN101951893A/zh active Pending
- 2009-01-02 EA EA201001085A patent/EA201001085A1/ru unknown
- 2009-01-02 MX MX2010007242A patent/MX2010007242A/es not_active Application Discontinuation
- 2009-01-02 EP EP09700111A patent/EP2237771A1/en not_active Withdrawn
- 2009-01-02 AU AU2009203123A patent/AU2009203123A1/en not_active Abandoned
- 2009-01-02 CA CA2711187A patent/CA2711187A1/en not_active Abandoned
- 2009-01-02 WO PCT/EP2009/050010 patent/WO2009083607A1/en active Application Filing
- 2009-01-02 KR KR1020107013387A patent/KR20100101106A/ko not_active Application Discontinuation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2712877C2 (ru) * | 2013-05-14 | 2020-01-31 | Новозимс А/С | Моющие композиции |
Also Published As
Publication number | Publication date |
---|---|
JP2011508755A (ja) | 2011-03-17 |
WO2009083607A1 (en) | 2009-07-09 |
EP2237771A1 (en) | 2010-10-13 |
MX2010007242A (es) | 2010-10-05 |
BRPI0906439A2 (pt) | 2018-12-04 |
KR20100101106A (ko) | 2010-09-16 |
CA2711187A1 (en) | 2009-07-09 |
US20110008423A1 (en) | 2011-01-13 |
AU2009203123A1 (en) | 2009-07-09 |
CN101951893A (zh) | 2011-01-19 |
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