EA200900900A1 - Производные замещенных 3-фенил-1-(фенилтиенил)пропан-1-онов и 3-фенил-1-(фенилфуранил)пропан-1-онов, их получение и применение - Google Patents

Производные замещенных 3-фенил-1-(фенилтиенил)пропан-1-онов и 3-фенил-1-(фенилфуранил)пропан-1-онов, их получение и применение

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Publication number
EA200900900A1
EA200900900A1 EA200900900A EA200900900A EA200900900A1 EA 200900900 A1 EA200900900 A1 EA 200900900A1 EA 200900900 A EA200900900 A EA 200900900A EA 200900900 A EA200900900 A EA 200900900A EA 200900900 A1 EA200900900 A1 EA 200900900A1
Authority
EA
Eurasian Patent Office
Prior art keywords
phenyl
propan
ones
substituted
phynyleneenyl
Prior art date
Application number
EA200900900A
Other languages
English (en)
Other versions
EA017449B1 (ru
Inventor
Жан-Франсуа Дельомель
Original Assignee
Жанфит
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Жанфит filed Critical Жанфит
Publication of EA200900900A1 publication Critical patent/EA200900900A1/ru
Publication of EA017449B1 publication Critical patent/EA017449B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
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  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
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  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)

Abstract

Настоящее изобретение относится к соединениям, полученным из замещенных 3-фенил-1-(тиен-2-ил)пропан-1-онов, фармацевтическим композициям, содержащим их, а также к их терапевтическому применению, в особенности в области здоровья человека и животных.
EA200900900A 2006-12-29 2007-12-28 Производные замещенных 3-фенил-1-(фенилтиенил)пропан-1-онов и 3-фенил-1-(фенилфуранил)пропан-1-онов, их получение и применение EA017449B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0656067A FR2910894A1 (fr) 2006-12-29 2006-12-29 Derives de 3-phenyl-1-(phenylthienyl)propan-1-one et de 3-phenyl-1-(phenylfuranyl)propan-1-one substitues, preparation et utilisation.
PCT/FR2007/052634 WO2008087366A2 (fr) 2006-12-29 2007-12-28 Derives de 3-phenyl-1-(phenylthienyl)propan-1-one et de 3-phenyl-1-(phenylfuranyl)propan-1-one substitues, preparation et utilisation

Publications (2)

Publication Number Publication Date
EA200900900A1 true EA200900900A1 (ru) 2010-02-26
EA017449B1 EA017449B1 (ru) 2012-12-28

Family

ID=38255443

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200900900A EA017449B1 (ru) 2006-12-29 2007-12-28 Производные замещенных 3-фенил-1-(фенилтиенил)пропан-1-онов и 3-фенил-1-(фенилфуранил)пропан-1-онов, их получение и применение

Country Status (14)

Country Link
US (1) US8088819B2 (ru)
EP (1) EP2079722B1 (ru)
JP (1) JP5371776B2 (ru)
KR (1) KR101505577B1 (ru)
CN (1) CN101605775B (ru)
AU (1) AU2007344310B2 (ru)
BR (1) BRPI0720633B8 (ru)
CA (1) CA2673761C (ru)
EA (1) EA017449B1 (ru)
ES (1) ES2544959T3 (ru)
FR (1) FR2910894A1 (ru)
IL (1) IL199488A (ru)
NZ (1) NZ577909A (ru)
WO (1) WO2008087366A2 (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en) 2011-09-27 2013-04-04 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
MX2014004853A (es) * 2011-10-26 2014-05-27 Hoffmann La Roche 1-cicloalquil- o 1-heterociclil-hidroxiimino-3-fenil-propanos.
WO2021169769A1 (zh) * 2020-02-28 2021-09-02 四川科伦博泰生物医药股份有限公司 芳香族化合物及其药物组合物和用途
AU2022272414A1 (en) 2021-05-11 2023-10-26 Genfit Elafibranor derivatives agonists of ppar for use in the treatment of sepsis
AU2022274304A1 (en) 2021-05-11 2023-10-26 Genfit Ppar-agonists for use in the treatment of liver failure

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0111523D0 (en) * 2001-05-11 2001-07-04 Glaxo Group Ltd Chemical compounds
US7186725B2 (en) 2003-01-03 2007-03-06 Genzyme Corporation Anti-inflammatory compositions and methods
WO2004063184A1 (en) * 2003-01-06 2004-07-29 Eli Lilly And Company Thiophene derivative ppar modulators
EA011305B1 (ru) * 2004-01-08 2009-02-27 Жанфит Производные 1,3-дифенилпроп-2-ен-1-она, способ их получения и применение
KR20070113253A (ko) * 2005-02-28 2007-11-28 닛뽕 케미파 가부시키가이샤 페록시좀 증식제 활성화 수용체 δ 의 활성화제

Also Published As

Publication number Publication date
US8088819B2 (en) 2012-01-03
JP5371776B2 (ja) 2013-12-18
CA2673761A1 (fr) 2008-07-24
KR20090102843A (ko) 2009-09-30
CN101605775A (zh) 2009-12-16
WO2008087366A3 (fr) 2008-10-23
IL199488A (en) 2013-10-31
EP2079722B1 (fr) 2015-06-17
AU2007344310B2 (en) 2013-08-15
CA2673761C (fr) 2016-02-23
BRPI0720633B8 (pt) 2021-05-25
BRPI0720633B1 (pt) 2019-11-26
EP2079722A2 (fr) 2009-07-22
FR2910894A1 (fr) 2008-07-04
JP2010514745A (ja) 2010-05-06
BRPI0720633A2 (pt) 2014-03-25
ES2544959T3 (es) 2015-09-07
CN101605775B (zh) 2014-11-12
KR101505577B1 (ko) 2015-03-30
EA017449B1 (ru) 2012-12-28
WO2008087366A2 (fr) 2008-07-24
AU2007344310A1 (en) 2008-07-24
NZ577909A (en) 2012-03-30
US20100029745A1 (en) 2010-02-04

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