EA200700637A1 - Соли донепезила, подходящие для получения фармацевтических композиций - Google Patents

Соли донепезила, подходящие для получения фармацевтических композиций

Info

Publication number
EA200700637A1
EA200700637A1 EA200700637A EA200700637A EA200700637A1 EA 200700637 A1 EA200700637 A1 EA 200700637A1 EA 200700637 A EA200700637 A EA 200700637A EA 200700637 A EA200700637 A EA 200700637A EA 200700637 A1 EA200700637 A1 EA 200700637A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutical compositions
salted
nipple
obtaining pharmaceutical
obtaining
Prior art date
Application number
EA200700637A
Other languages
English (en)
Inventor
Тибор Мезеи
Дьюла Шимиг
Дьюла Лукач
Марта Порч-Маккаи
Балаж Вольк
Эникё Мольнар
Валерия Хофманне Фекете
Original Assignee
Эгиш Дьёдьсердьяр Нирт.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эгиш Дьёдьсердьяр Нирт. filed Critical Эгиш Дьёдьсердьяр Нирт.
Publication of EA200700637A1 publication Critical patent/EA200700637A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

Настоящее изобретение относится к солям донепезила, подходящим для получения фармацевтических композиций. Кроме того, настоящее изобретение относится к способу получения указанных солей, содержащим их фармацевтическим композициям и к применению указанных соединений для лечения болезней.
EA200700637A 2004-09-15 2005-09-12 Соли донепезила, подходящие для получения фармацевтических композиций EA200700637A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0401850A HUP0401850A3 (en) 2004-09-15 2004-09-15 Donepezil salts for producing pharmaceutical composition
PCT/HU2005/000102 WO2006030249A1 (en) 2004-09-15 2005-09-12 Donepezil salts suitable for the preparation of pharmaceutical compositions

Publications (1)

Publication Number Publication Date
EA200700637A1 true EA200700637A1 (ru) 2007-08-31

Family

ID=89985497

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200700637A EA200700637A1 (ru) 2004-09-15 2005-09-12 Соли донепезила, подходящие для получения фармацевтических композиций

Country Status (14)

Country Link
US (1) US20080194628A1 (ru)
EP (1) EP1817286A1 (ru)
CN (1) CN101039910A (ru)
BG (1) BG109855A (ru)
CZ (1) CZ2007248A3 (ru)
EA (1) EA200700637A1 (ru)
HU (1) HUP0401850A3 (ru)
IL (1) IL181827A0 (ru)
NO (1) NO20071912L (ru)
PL (1) PL382842A1 (ru)
RU (1) RU2382032C2 (ru)
SK (1) SK50342007A3 (ru)
UA (1) UA88481C2 (ru)
WO (1) WO2006030249A1 (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004046497A1 (de) * 2004-09-23 2006-04-06 Helm Ag Donepezil-Salze
JP2008514691A (ja) * 2004-09-29 2008-05-08 ケマジス リミティド 薬学的に純粋な非晶質塩酸ドネペジルを製造するための精製されたマレイン酸ドネペジルの使用
US20090171094A1 (en) * 2005-07-15 2009-07-02 Kazuhide Ashizawa 1-benzyl-4-[(5, 6-dimethoxy- 1- indanon)- 2- yl]-methyl piperidine p-toluenesulfonate or crystal thereof
US20100113793A1 (en) * 2006-03-20 2010-05-06 Ind-Swift Laboratories Limited Process for the Preparation of Highly Pure Donepezil
GB0609835D0 (en) * 2006-05-18 2006-06-28 Pliva Istrazivanje I Razvoj D Impurities of a pharmaceutical product
CN101167697B (zh) * 2006-10-26 2011-03-30 中国科学院上海药物研究所 多奈哌齐类化合物长效缓控释组合物及其制备方法
JP5426554B2 (ja) * 2007-09-28 2014-02-26 天津和美生物技▲術▼有限公司 ドネペジル塩、その多形体、その製造方法、応用方法および組成物
WO2010033045A1 (en) * 2008-09-16 2010-03-25 Igor Anatolievich Pomytkin Compositions and methods for prevention or treatment of beta amyloid deposition
US20140243278A1 (en) * 2011-07-05 2014-08-28 Sunil Sadanand Nadkarni Acid Addition Salt of Donepezil and Pharmaceutical Composition Thereof
EP2586436A1 (en) 2011-10-31 2013-05-01 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Use of anti-connexin agents for enhancing the therapeutic effect of acetylcholinesterase inhibitor
WO2013078608A1 (en) 2011-11-29 2013-06-06 Ziqiang Gu Donepezil pamoate and methods of making and using the same
KR101811797B1 (ko) * 2013-04-03 2017-12-22 동국제약 주식회사 도네페질을 포함하는 비경구투여용 약제학적 조성물
WO2018153315A1 (zh) * 2017-02-23 2018-08-30 上海华汇拓医药科技有限公司 一种多奈哌齐半帕莫酸盐的粉针剂、包含其的组合物及它们的制备方法
WO2020111719A2 (ko) * 2018-11-26 2020-06-04 연세대학교 산학협력단 도네페질 공융혼합물 및 이의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
WO2000059544A1 (fr) * 1999-03-31 2000-10-12 Eisai Co., Ltd. Compositions stabilisees contenant des medicaments nootropes
CA2382117C (en) * 1999-09-01 2009-11-10 Eisai Co., Ltd. 4-substituted piperidine compound
EP1285656A4 (en) * 2000-04-13 2006-07-12 Eisai Co Ltd ACETYLCHOLINESTERASE HEMMER CONTAINING 1-BENZYLPYRIDINIUM SALT
US7439365B2 (en) * 2003-11-17 2008-10-21 Usv, Ltd. Pharmaceutical salt of (1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl] methyl piperidine (Donepezil)

Also Published As

Publication number Publication date
RU2007114082A (ru) 2008-10-27
RU2382032C2 (ru) 2010-02-20
IL181827A0 (en) 2007-07-04
EP1817286A1 (en) 2007-08-15
NO20071912L (no) 2007-06-07
CZ2007248A3 (cs) 2007-06-20
HUP0401850A3 (en) 2008-03-28
HUP0401850A2 (en) 2006-11-28
UA88481C2 (ru) 2009-10-26
SK50342007A3 (sk) 2007-07-06
HU0401850D0 (en) 2004-11-29
CN101039910A (zh) 2007-09-19
US20080194628A1 (en) 2008-08-14
BG109855A (bg) 2008-04-30
PL382842A1 (pl) 2008-01-21
WO2006030249A1 (en) 2006-03-23

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