EA200602187A1 - Фармацевтическая композиция и способ её получения - Google Patents
Фармацевтическая композиция и способ её полученияInfo
- Publication number
- EA200602187A1 EA200602187A1 EA200602187A EA200602187A EA200602187A1 EA 200602187 A1 EA200602187 A1 EA 200602187A1 EA 200602187 A EA200602187 A EA 200602187A EA 200602187 A EA200602187 A EA 200602187A EA 200602187 A1 EA200602187 A1 EA 200602187A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- pharmaceutical composition
- obtaining
- weight
- present
- admixture
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 229960000528 amlodipine Drugs 0.000 abstract 1
- HTIQEAQVCYTUBX-UHFFFAOYSA-N amlodipine Chemical compound CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1Cl HTIQEAQVCYTUBX-UHFFFAOYSA-N 0.000 abstract 1
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- 239000000945 filler Substances 0.000 abstract 1
- 229960002394 lisinopril Drugs 0.000 abstract 1
- RLAWWYSOJDYHDC-BZSNNMDCSA-N lisinopril Chemical compound C([C@H](N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(O)=O)C(O)=O)CC1=CC=CC=C1 RLAWWYSOJDYHDC-BZSNNMDCSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Настоящее изобретение относится к фармацевтической композиции, содержащей в качестве активных ингредиентов от 0,3 до 30 мас.% амлодипина бесилата и от 0,1 до 75 мас.% лизиноприла дигидрата, в смеси с одним или более наполнителей, традиционно используемых в фармацевтической промышленности, при условии, что наполнитель не является кальциевой солью фосфорной кислоты. Настоящее изобретение также предусматривает способ получения указанной выше фармацевтической композиции.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0401170A HUP0401170A2 (en) | 2004-06-10 | 2004-06-10 | Pharmaceutical composition comprising amlodipine besilate and lisinopril dihydrate and process for |
| PCT/HU2005/000064 WO2005120502A1 (en) | 2004-06-10 | 2005-06-09 | New pharmaceutical composition and process for the preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200602187A1 true EA200602187A1 (ru) | 2007-04-27 |
| EA010288B1 EA010288B1 (ru) | 2008-08-29 |
Family
ID=89985289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200602187A EA010288B1 (ru) | 2004-06-10 | 2005-06-09 | Фармацевтическая композиция, содержащая амлодипина бесилат и лизиноприла дигидрат, и способ её получения |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1765342B9 (ru) |
| AT (1) | ATE486599T1 (ru) |
| CY (1) | CY1111484T1 (ru) |
| DE (1) | DE602005024554D1 (ru) |
| DK (1) | DK1765342T3 (ru) |
| EA (1) | EA010288B1 (ru) |
| ES (1) | ES2354618T3 (ru) |
| HR (1) | HRP20110034T1 (ru) |
| HU (2) | HUP0401170A2 (ru) |
| ME (1) | ME01935B (ru) |
| PL (1) | PL1765342T4 (ru) |
| PT (1) | PT1765342E (ru) |
| RS (1) | RS51677B (ru) |
| SI (1) | SI1765342T1 (ru) |
| WO (1) | WO2005120502A1 (ru) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG183449A1 (en) * | 2010-02-24 | 2012-09-27 | Sanofi Aventis Deutschland | Solid pharmaceutical formulations of ramipril and amlodipine besylate, and their preparation |
| RU2483728C1 (ru) * | 2011-09-29 | 2013-06-10 | Общество с ограниченной ответственностью "Озон" | Комбинированное гипотензивное средство и способ его получения |
| PL227900B1 (pl) * | 2012-11-15 | 2018-01-31 | Adamed Spolka Z Ograniczona Odpowiedzialnoscia | Kompozycja farmaceutyczna zawierająca inhibitor ACE i bloker kanałów wapniowych, sposób jej wytwarzania i jednostka dawkowania zawierająca tę kompozycję |
| CN105194647A (zh) * | 2014-06-30 | 2015-12-30 | 南京瑞尔医药有限公司 | 一种含有赖诺普利和苯磺酸氨氯地平的药物组合物及其制备方法 |
| CN106333948A (zh) * | 2016-08-23 | 2017-01-18 | 成都尚药科技有限公司 | 含有苯磺酸氨氯地平和二水合赖诺普利的药物及制备方法 |
| KR102622953B1 (ko) | 2017-04-25 | 2024-01-09 | 오츠카 세이야쿠 가부시키가이샤 | 섭취 가능한 이벤트 마커를 사용한 리시노프릴 조성물 |
| GB2595203A (en) | 2020-03-03 | 2021-11-24 | Alkaloid Ad Skopje | Formulation |
| WO2024052498A1 (en) * | 2022-09-07 | 2024-03-14 | Kinast Lasse | An immediate-release oral pharmaceutical form of amlodipine with increased api content |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9706957A (es) * | 1995-03-16 | 1997-11-29 | Pfizer | Composicion que contiene amlodipina, o una sal, o felodipina y un inhibidor de enzima convertidora de angiotensina. |
| HUP0202416A3 (en) | 2002-07-24 | 2006-01-30 | Richter Gedeon Vegyeszet | Novel pharmaceutical combination and it's use for the treatment of certain cardiovascular disorders |
-
2004
- 2004-06-10 HU HU0401170A patent/HUP0401170A2/hu unknown
-
2005
- 2005-06-09 DK DK05751188.3T patent/DK1765342T3/da active
- 2005-06-09 ES ES05751188T patent/ES2354618T3/es active Active
- 2005-06-09 EA EA200602187A patent/EA010288B1/ru unknown
- 2005-06-09 ME MEP-2010-496A patent/ME01935B/me unknown
- 2005-06-09 RS RS20100496A patent/RS51677B/en unknown
- 2005-06-09 PT PT05751188T patent/PT1765342E/pt unknown
- 2005-06-09 WO PCT/HU2005/000064 patent/WO2005120502A1/en active Application Filing
- 2005-06-09 PL PL05751188.3T patent/PL1765342T4/pl unknown
- 2005-06-09 DE DE602005024554T patent/DE602005024554D1/de active Active
- 2005-06-09 HU HUE05751188A patent/HUE009867T4/hu unknown
- 2005-06-09 SI SI200531194T patent/SI1765342T1/sl unknown
- 2005-06-09 EP EP05751188A patent/EP1765342B9/en active Active
- 2005-06-09 AT AT05751188T patent/ATE486599T1/de active
-
2010
- 2010-12-30 CY CY20101101203T patent/CY1111484T1/el unknown
-
2011
- 2011-01-18 HR HR20110034T patent/HRP20110034T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1765342E (pt) | 2010-12-20 |
| HUE009867T4 (hu) | 2022-01-28 |
| SI1765342T1 (sl) | 2011-02-28 |
| HRP20110034T1 (hr) | 2011-02-28 |
| RS51677B (en) | 2011-10-31 |
| EP1765342A1 (en) | 2007-03-28 |
| CY1111484T1 (el) | 2015-08-05 |
| DE602005024554D1 (de) | 2010-12-16 |
| HU0401170D0 (en) | 2004-08-30 |
| PL1765342T3 (pl) | 2011-04-29 |
| DK1765342T3 (da) | 2011-01-24 |
| EP1765342B9 (en) | 2011-02-23 |
| EP1765342B1 (en) | 2010-11-03 |
| ATE486599T1 (de) | 2010-11-15 |
| PL1765342T4 (pl) | 2022-11-07 |
| HUP0401170A2 (en) | 2006-09-28 |
| HUE009867T2 (ru) | 2011-05-30 |
| EA010288B1 (ru) | 2008-08-29 |
| ES2354618T3 (es) | 2011-03-16 |
| WO2005120502A1 (en) | 2005-12-22 |
| ME01935B (me) | 2011-10-31 |
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