EA200600946A1 - Способы продуцирования аполипопротеинов в трансгенных растениях - Google Patents

Способы продуцирования аполипопротеинов в трансгенных растениях

Info

Publication number
EA200600946A1
EA200600946A1 EA200600946A EA200600946A EA200600946A1 EA 200600946 A1 EA200600946 A1 EA 200600946A1 EA 200600946 A EA200600946 A EA 200600946A EA 200600946 A EA200600946 A EA 200600946A EA 200600946 A1 EA200600946 A1 EA 200600946A1
Authority
EA
Eurasian Patent Office
Prior art keywords
nucleic acid
apolipoprotein
plants
methods
apolipoproteins
Prior art date
Application number
EA200600946A
Other languages
English (en)
Other versions
EA015167B1 (ru
Inventor
Морис М. Молони
Александра Рейд
Original Assignee
Сембайосиз Джинетикс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сембайосиз Джинетикс Инк. filed Critical Сембайосиз Джинетикс Инк.
Publication of EA200600946A1 publication Critical patent/EA200600946A1/ru
Publication of EA015167B1 publication Critical patent/EA015167B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Botany (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Описаны способы продуцирования аполипопротеина в растениях. В одном варианте осуществления изобретение относится к способу экспрессии аполипопротеина в растениях, предусматривающему (а) создание конструкции химерной нуклеиновой кислоты, содержащей в 5'-3' направлении транскрипции в качестве функционально связанных компонентов: (i) последовательность нуклеиновой кислоты, способную контролировать экспрессию в клетках растений и (ii) последовательность нуклеиновой кислоты, кодирующую полипептид аполипопротеина; (b) введение конструкции химерной нуклеиновой кислоты в клетку растения; и выращивание клетки растения в зрелое растение, способное давать семена, где семена экспрессируют аполипопротеин.
EA200600946A 2003-11-14 2004-11-15 Способ обеспечения экспрессии аполипопротеина в растениях и растения и их семена, содержащие аполипопротеин EA015167B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51960603P 2003-11-14 2003-11-14
US57973304P 2004-06-16 2004-06-16
PCT/CA2004/001960 WO2005047455A2 (en) 2003-11-14 2004-11-15 Methods for the production of apolipoproteins in transgenic plants

Publications (2)

Publication Number Publication Date
EA200600946A1 true EA200600946A1 (ru) 2006-12-29
EA015167B1 EA015167B1 (ru) 2011-06-30

Family

ID=34594972

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200600946A EA015167B1 (ru) 2003-11-14 2004-11-15 Способ обеспечения экспрессии аполипопротеина в растениях и растения и их семена, содержащие аполипопротеин

Country Status (16)

Country Link
US (2) US7786352B2 (ru)
EP (1) EP1682664A4 (ru)
JP (1) JP2007510420A (ru)
KR (1) KR20060124633A (ru)
CN (1) CN1906296B (ru)
AR (1) AR047769A1 (ru)
AU (1) AU2004289720B2 (ru)
BR (1) BRPI0416589A (ru)
CA (1) CA2544239A1 (ru)
EA (1) EA015167B1 (ru)
IL (1) IL175248A0 (ru)
MX (1) MXPA06005363A (ru)
NO (1) NO20062480L (ru)
NZ (1) NZ547024A (ru)
TW (1) TW200526778A (ru)
WO (1) WO2005047455A2 (ru)

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CN100385005C (zh) * 2000-12-19 2008-04-30 塞姆柏奥希斯遗传学公司 制备多聚体蛋白质的方法和相关的组合物
US9487575B2 (en) * 2004-07-14 2016-11-08 The Regents Of The University Of California Compositions and methods for treatment of gynecologic cancers
WO2007005928A2 (en) * 2005-07-01 2007-01-11 Cornell Research Foundation Oleosin genes and promoters from coffee
EP2057270A1 (en) * 2006-08-10 2009-05-13 Plantechno SRL In-plant production of dimeric and/or oligomeric (comprising three or more units) forms of human apo a-1 protein muteins
JP5242570B2 (ja) 2006-08-31 2013-07-24 モンサント テクノロジー エルエルシー 単子葉を急速に形質転換する方法
JP2009201435A (ja) * 2008-02-28 2009-09-10 Toyota Motor Corp 種子中の油脂量の評価方法及び油脂含量が変化した植物体のスクリーニング方法
EP2298883B1 (en) * 2008-05-28 2016-07-27 Kyoto University Novel selection marker gene and use thereof
EP2488876B1 (en) 2009-10-13 2017-03-01 Nanostring Technologies, Inc Protein detection via nanoreporters
US9745362B2 (en) * 2009-12-09 2017-08-29 Shengjun An Seed-specific expression vector and its construction methods and applications
EP2468871A1 (en) * 2010-12-23 2012-06-27 Philip Morris Products S.A. Method for producing apolipoprotein in plants
US20140220217A1 (en) 2011-07-12 2014-08-07 Maraxi, Inc. Method and compositions for consumables
RU2653751C2 (ru) 2011-07-12 2018-05-14 Импоссибл Фудз Инк Способы и композиции для предметов потребления
CN103796530A (zh) 2011-07-12 2014-05-14 马拉克西公司 用于消费品的方法和组合物
WO2014110539A1 (en) 2013-01-11 2014-07-17 Maraxi, Inc. Methods and compositions for consumables
US10039306B2 (en) 2012-03-16 2018-08-07 Impossible Foods Inc. Methods and compositions for consumables
US9539300B2 (en) * 2012-03-31 2017-01-10 The Regents Of The University Of California Modulating disease through genetic engineering of plants
EP2943077B1 (en) 2013-01-11 2018-10-31 Impossible Foods Inc. Non-dairy ricotta cheese replica
AU2015240911B2 (en) 2014-03-31 2018-11-08 Impossible Foods Inc. Ground meat replicas
KR20170003611A (ko) 2014-05-02 2017-01-09 세레니스 쎄라퓨틱스 홀딩 에스에이 Ｈｄｌ 요법 마커
TW201625678A (zh) * 2014-11-21 2016-07-16 美國芝加哥州立大學 合成肽
US20160208274A1 (en) * 2015-01-21 2016-07-21 Northeastern State University Blood clot-dissolving proteins produced in seeds
EP3088414A1 (de) * 2015-04-30 2016-11-02 Euroimmun Medizinische Labordiagnostika AG Verbesserter nachweis von nussallergien
IT201600081193A1 (it) * 2016-08-02 2018-02-02 Grg Gene Tech Sa COMPOSIZIONI PER SOMMINISTRAZIONE DI ApoA1 E DOSAGGI
WO2019190930A2 (en) * 2018-03-25 2019-10-03 Emendobio Inc. Differential knockout of an allele of a heterozygous apolipoprotein a1 (apoa1) gene
CN114990134B (zh) * 2022-05-30 2023-07-25 扬州大学 一种水稻油体蛋白基因OsOle6及其编码蛋白与应用
CN115290776A (zh) * 2022-07-26 2022-11-04 云南大学 瘤牛锥虫病抗性蛋白的应用

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US4956282A (en) * 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
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Also Published As

Publication number Publication date
JP2007510420A (ja) 2007-04-26
US20120059150A1 (en) 2012-03-08
WO2005047455A3 (en) 2005-07-21
EP1682664A4 (en) 2008-04-02
BRPI0416589A (pt) 2007-01-30
TW200526778A (en) 2005-08-16
AR047769A1 (es) 2006-02-22
MXPA06005363A (es) 2006-07-19
US7786352B2 (en) 2010-08-31
IL175248A0 (en) 2006-09-05
KR20060124633A (ko) 2006-12-05
NZ547024A (en) 2009-09-25
CA2544239A1 (en) 2005-05-26
WO2005047455A2 (en) 2005-05-26
AU2004289720B2 (en) 2011-02-03
CN1906296B (zh) 2013-09-11
AU2004289720A1 (en) 2005-05-26
EP1682664A2 (en) 2006-07-26
US20050172359A1 (en) 2005-08-04
EA015167B1 (ru) 2011-06-30
CN1906296A (zh) 2007-01-31
NO20062480L (no) 2006-08-09

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

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