EA200401564A1 - Системы устранения трансдермальных средств доставки для предотвращения неправильного использования активных веществ, содержащихся в них - Google Patents

Системы устранения трансдермальных средств доставки для предотвращения неправильного использования активных веществ, содержащихся в них

Info

Publication number
EA200401564A1
EA200401564A1 EA200401564A EA200401564A EA200401564A1 EA 200401564 A1 EA200401564 A1 EA 200401564A1 EA 200401564 A EA200401564 A EA 200401564A EA 200401564 A EA200401564 A EA 200401564A EA 200401564 A1 EA200401564 A1 EA 200401564A1
Authority
EA
Eurasian Patent Office
Prior art keywords
transdermal delivery
delivery device
active component
contained
elimination
Prior art date
Application number
EA200401564A
Other languages
English (en)
Other versions
EA007240B1 (ru
Inventor
Карл Дж. Бэкер
Игорь Шевчук
Original Assignee
Еуро-Селтик С. А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Еуро-Селтик С. А. filed Critical Еуро-Селтик С. А.
Publication of EA200401564A1 publication Critical patent/EA200401564A1/ru
Publication of EA007240B1 publication Critical patent/EA007240B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
    • B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
    • B09B3/00—Destroying solid waste or transforming solid waste into something useful or harmless
    • B09B3/0075—Disposal of medical waste
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
    • B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
    • B09B2101/00—Type of solid waste
    • B09B2101/65—Medical waste
    • B09B2101/68—Transdermal patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Processing Of Solid Wastes (AREA)

Abstract

Данное изобретение относится к системе устранения трансдермального средства доставки, содержащего по меньшей мере один фармацевтически активный компонент. Система содержит по меньшей мере один лист или подложку, на которой имеется адгезивное покрытие, и один или несколько из следующих компонентов: (а) мономер и, возможно, сомономер(ы), которые полимеризуются; (б) инициатор и, возможно, соинициатор(ы) для инициирования полимеризации; (в) по меньшей мере один сшивающий агент для сшивки (со)полимера и (г) по меньшей мере один деактивирующий агент для химического изменения, разложения и/или деактивации активного компонента(ов), содержащегося в трансдермальном средстве доставки, такого как опиоидный антагонист или агент, деактивирующий опиоидный агонист, с тем, чтобы проявления эйфории, вызванные активным компонентом(ами), содержащимся в трансдермальном средстве доставки, по меньшей мере, временно ингибировались, уменьшались или прекращались in vivo, причём по меньшей мере один лист или подложка с нанесённым адгезивом иммобилизует или изолирует и предотвращает, ингибирует или снижает неправильное употребление или злоупотребление активным компонентом, содержащимся по меньшей мере в одном трансдермальном средстве доставки.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200401564A 2002-06-10 2003-06-10 Системы дезактивации активного вещества в трансдермальном средстве EA007240B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38780002P 2002-06-10 2002-06-10
PCT/US2003/018256 WO2003103673A1 (en) 2002-06-10 2003-06-10 Disposal systems of transdermal delivery devices to prevent misuse of the active agents contained therein

Publications (2)

Publication Number Publication Date
EA200401564A1 true EA200401564A1 (ru) 2005-08-25
EA007240B1 EA007240B1 (ru) 2006-08-25

Family

ID=29736367

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200401564A EA007240B1 (ru) 2002-06-10 2003-06-10 Системы дезактивации активного вещества в трансдермальном средстве

Country Status (22)

Country Link
US (2) US20040033255A1 (ru)
EP (4) EP2266565A1 (ru)
JP (3) JP4949625B2 (ru)
KR (2) KR20110120358A (ru)
CN (2) CN101455649B (ru)
AT (1) ATE355061T1 (ru)
AU (2) AU2003251482A1 (ru)
CA (1) CA2488915C (ru)
CY (1) CY1107630T1 (ru)
DE (1) DE60312160T2 (ru)
DK (1) DK1513532T3 (ru)
EA (1) EA007240B1 (ru)
ES (1) ES2283812T3 (ru)
IL (1) IL165517A0 (ru)
MX (1) MXPA04012333A (ru)
NO (1) NO334455B1 (ru)
NZ (1) NZ537180A (ru)
PT (1) PT1513532E (ru)
SI (1) SI1513532T1 (ru)
UA (1) UA82194C2 (ru)
WO (1) WO2003103673A1 (ru)
ZA (1) ZA200409495B (ru)

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CA2488915A1 (en) 2003-12-18
DE60312160T2 (de) 2007-10-31
JP5507367B2 (ja) 2014-05-28
KR20110120358A (ko) 2011-11-03
ATE355061T1 (de) 2006-03-15
CN101455649A (zh) 2009-06-17
NO334455B1 (no) 2014-03-10
CN100525767C (zh) 2009-08-12
DE60312160D1 (de) 2007-04-12
KR101407131B1 (ko) 2014-06-19
MXPA04012333A (es) 2005-02-25
ZA200409495B (en) 2006-05-31
KR20050020977A (ko) 2005-03-04
AU2009217420B2 (en) 2013-06-13
SI1513532T1 (sl) 2007-08-31
JP2011016802A (ja) 2011-01-27
CN101455649B (zh) 2014-02-26
UA82194C2 (ru) 2008-03-25
EP1513532A1 (en) 2005-03-16
US20040033255A1 (en) 2004-02-19
AU2009217420A1 (en) 2009-10-15
WO2003103673A1 (en) 2003-12-18
US20080274168A1 (en) 2008-11-06
PT1513532E (pt) 2007-05-31
NZ537180A (en) 2008-03-28
NO20050126L (no) 2005-01-10
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AU2003251482A1 (en) 2003-12-22
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JP2005538058A (ja) 2005-12-15
EP2266565A1 (en) 2010-12-29
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EA007240B1 (ru) 2006-08-25
CN1658878A (zh) 2005-08-24
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