EA200400323A1 - Аралкилтетрагидропиридины, их получение и содержащие их фармацевтические композиции - Google Patents

Аралкилтетрагидропиридины, их получение и содержащие их фармацевтические композиции

Info

Publication number
EA200400323A1
EA200400323A1 EA200400323A EA200400323A EA200400323A1 EA 200400323 A1 EA200400323 A1 EA 200400323A1 EA 200400323 A EA200400323 A EA 200400323A EA 200400323 A EA200400323 A EA 200400323A EA 200400323 A1 EA200400323 A1 EA 200400323A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutical compositions
aralkiltetrahydropyridines
receiving
international
solvates
Prior art date
Application number
EA200400323A
Other languages
English (en)
Other versions
EA007324B1 (ru
Inventor
Марко Барони
Бернар Бурри
Розанна Кардамон
Пьер Казелла
Original Assignee
Санофи-Синтелябо
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Санофи-Синтелябо filed Critical Санофи-Синтелябо
Publication of EA200400323A1 publication Critical patent/EA200400323A1/ru
Publication of EA007324B1 publication Critical patent/EA007324B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Abstract

Изобретение касается соединений формулы I, где X представляет собой N или CH; Rпредставляет собой атом водорода или галогена или группу CF; n означает целое число от 1 до 5; A представляет собой частично насыщенное бициклическое или трициклическое углеродное соединение, а также их солей или сольватов, их N-оксидов, фармацевтических композиций, содержащих их, способа их получения и промежуточных соединений, синтезируемых в указанном способе.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200400323A 2001-10-18 2002-10-14 Аралкилтетрагидропиридины, их получение и содержащие их фармацевтические композиции EA007324B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0113469A FR2831166B1 (fr) 2001-10-18 2001-10-18 Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant
PCT/FR2002/003508 WO2003033466A1 (fr) 2001-10-18 2002-10-14 Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
EA200400323A1 true EA200400323A1 (ru) 2004-10-28
EA007324B1 EA007324B1 (ru) 2006-08-25

Family

ID=8868455

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200400323A EA007324B1 (ru) 2001-10-18 2002-10-14 Аралкилтетрагидропиридины, их получение и содержащие их фармацевтические композиции

Country Status (22)

Country Link
US (2) US7326723B2 (ru)
EP (1) EP1438291B1 (ru)
JP (2) JP4524107B2 (ru)
KR (1) KR100935787B1 (ru)
CN (2) CN101096337A (ru)
AT (1) ATE303991T1 (ru)
AU (1) AU2002360117B2 (ru)
BR (1) BR0213359A (ru)
CA (1) CA2460822C (ru)
DE (1) DE60206068T2 (ru)
EA (1) EA007324B1 (ru)
FR (1) FR2831166B1 (ru)
HK (1) HK1065543A1 (ru)
HU (1) HUP0401713A3 (ru)
IL (2) IL160820A0 (ru)
IS (1) IS2486B (ru)
MX (1) MXPA04003568A (ru)
NO (1) NO326490B1 (ru)
NZ (1) NZ531846A (ru)
PL (1) PL368802A1 (ru)
WO (1) WO2003033466A1 (ru)
ZA (1) ZA200402059B (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04003480A (es) 2001-10-15 2004-07-30 Janssen Pharmaceutica Nv Derivados de 4-fenil-4-(1h-imidazol-2-il)-piperidina sustituida para la reduccion de la lesion isquemica.
US20060276465A1 (en) * 2003-12-26 2006-12-07 Eisai R&D Management Co., Ltd. 1,2-di(cyclic) substituted benzene compounds
MY140489A (en) 2003-12-26 2009-12-31 Eisai R&D Man Co Ltd 1,2-di (cyclic) substituted benzene compounds
JP4966017B2 (ja) 2004-12-20 2012-07-04 エーザイ・アール・アンド・ディー・マネジメント株式会社 １−シクロプロピルメチル−４−［２−（３，３，５，５−テトラメチルシクロヘキシル）フェニル］ピペラジンの塩および結晶
US7410971B2 (en) 2004-12-24 2008-08-12 Eisai R&D Management Co., Ltd. 1,2-di(cyclic)substituted benzene compounds
MY144974A (en) * 2005-06-14 2011-11-30 Eisai R&D Man Co Ltd 1,2-di(cyclic) substituted benzene derivatives
US9608205B2 (en) 2005-09-15 2017-03-28 Lg Chem, Ltd. Organic compound and organic light emitting device using the same
US9493383B2 (en) 2005-09-15 2016-11-15 Lg Chem, Ltd. Organic compound and organic light emitting device using the same
US8298683B2 (en) * 2005-09-15 2012-10-30 Lg Chem, Ltd. Organic compound and organic light emitting device using the same
EP2294177B8 (en) * 2008-06-05 2016-12-21 InvivoSciences, Inc. Three dimensional tissues for high-throughput assays

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3804878A (en) * 1969-09-08 1974-04-16 Ciba Geigy Corp Hydrogenated araliphatic acids
ES2068497T3 (es) * 1990-03-12 1995-04-16 Yamanouchi Pharma Co Ltd Derivados de urea, su produccion, y composiciones farmaceuticas que los contienen.
FR2662442A1 (fr) * 1990-05-23 1991-11-29 Midy Spa Trifluoromethylphenyltetrahydropyridines n-substituees procede pour leur preparation, intermediaires du procede et compositions pharmaceutiques les contenant.
EP0769015B1 (en) * 1994-07-04 2001-03-14 Takeda Chemical Industries, Ltd. Phosphonic acid compounds, their production and use
FR2734819B1 (fr) * 1995-05-31 1997-07-04 Adir Nouveaux composes de la piperazine, de la piperidine et de la 1,2,5,6-tetrahydropyridine, leur procede de preparation et les compositions pharmaceutiques les contenant
FR2762514B1 (fr) * 1997-04-29 1999-10-22 Sanofi Sa Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation
FR2763847B1 (fr) * 1997-05-28 2003-06-06 Sanofi Sa Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
US6070784A (en) * 1998-07-08 2000-06-06 The Boeing Company Contact backup roller approach to FSW process
ATE271554T1 (de) * 1999-10-22 2004-08-15 Sanofi Synthelabo Phenyl- und pyridyl-tetrahydro-pyridine mit tnf inhibitorischer wirkung
CN1244577C (zh) * 1999-12-30 2006-03-08 H.隆德贝克有限公司 4－苯基－1－哌嗪基、－哌啶基和－四氢吡啶基衍生物
FR2803593B1 (fr) * 2000-01-06 2002-02-15 Sanofi Synthelabo Nouvelles tetrahydropyridines, procede pour leur preparation et compositions pharmaceutiques les contenant
WO2002085888A1 (fr) * 2001-04-20 2002-10-31 Sanofi-Synthelabo Tetrahydropyridyl-alkyl-heterocycles, procede pour leur preparation et compositions pharmaceutiques les contenants
FR2823749B1 (fr) * 2001-04-20 2004-02-20 Sanofi Synthelabo Phenyl- et pyridyl-piperidines, procede pour leur preparation et compositions pharmaceutiques les contenant
JP3687912B2 (ja) * 2002-08-29 2005-08-24 東芝テック株式会社 プリンタユニット

Also Published As

Publication number Publication date
WO2003033466A1 (fr) 2003-04-24
JP4524107B2 (ja) 2010-08-11
JP2005505621A (ja) 2005-02-24
KR100935787B1 (ko) 2010-01-06
EA007324B1 (ru) 2006-08-25
US20050014795A1 (en) 2005-01-20
AU2002360117B2 (en) 2008-07-17
IL160820A0 (en) 2004-08-31
CN1571770A (zh) 2005-01-26
IS2486B (is) 2008-12-15
BR0213359A (pt) 2004-10-26
HUP0401713A3 (en) 2012-08-28
DE60206068D1 (de) 2005-10-13
HK1065543A1 (en) 2005-02-25
IL160820A (en) 2009-06-15
CN101096337A (zh) 2008-01-02
ZA200402059B (en) 2005-03-15
EP1438291A1 (fr) 2004-07-21
FR2831166A1 (fr) 2003-04-25
CA2460822A1 (en) 2003-04-24
US20080097117A1 (en) 2008-04-24
JP2010120961A (ja) 2010-06-03
NO326490B1 (no) 2008-12-15
PL368802A1 (en) 2005-04-04
KR20050036866A (ko) 2005-04-20
HUP0401713A2 (hu) 2004-12-28
ATE303991T1 (de) 2005-09-15
MXPA04003568A (es) 2004-07-30
CN100335464C (zh) 2007-09-05
NO20041573L (no) 2004-07-07
NZ531846A (en) 2005-10-28
IS7181A (is) 2004-03-11
EP1438291B1 (fr) 2005-09-07
FR2831166B1 (fr) 2004-02-27
DE60206068T2 (de) 2006-07-13
CA2460822C (en) 2011-01-04
US7858824B2 (en) 2010-12-28
US7326723B2 (en) 2008-02-05

Similar Documents

Publication Publication Date Title
EA200200716A1 (ru) Арилконденсированные азаполициклические соединения
EA200201179A1 (ru) Производные 2-аминокарбонил-9h-пурина
EA200201141A1 (ru) Производные тропана, полезные для терапии
EA200000334A1 (ru) Производные карбоксамидотиазолов, их получение, содержащие их фармацевтические композиции
EA200300428A1 (ru) Антагонисты метаботропных рецепторов глутамата
EA200600358A1 (ru) Фенил- или пиридиламидные соединения в качестве антагонистов простагландина е2
EA200200912A1 (ru) Новые производные индолин-2-она, их получение и их применение в качестве лигандов рецепторов окситоцина
EA200200774A1 (ru) Новые соединения, обладающие гиполипидемической, гипохолестеринемической активностью, способ их получения и содержащие их композиции
EA200400323A1 (ru) Аралкилтетрагидропиридины, их получение и содержащие их фармацевтические композиции
EA200400748A1 (ru) Агонисты рецепторов, активируемых пероксисомным пролифератором
EA200200732A1 (ru) Замещенные производные фенилпиперазина, их получение и применение
EA200000431A2 (ru) Новые замещенные димерные соединения, способ их получения и фармацевтические композиции, содержащие их
EA200101234A1 (ru) Новые производные аминотиазола, их получение и содержащие их фармацевтические композиции
EA200200729A1 (ru) Производные 4-фенил-1-пиперазинила, -пиперидинила и -тетрагидропиридила
EA200301317A1 (ru) Производные аминохинолина и его применение в качестве лигандов аденозина a3
EA200400848A1 (ru) Производные триазолохинолина, применимые в качестве лигандов аденозиновых рецепторов
EA200200611A1 (ru) Новые тетрагидропиридины, способ их получения и содержащие их фармацевтические композиции
EA200001165A1 (ru) Производные тетрагидрохинолина в качестве антагонистов глицина
ES2060079T3 (es) Procedimiento para la preparacion de un carboxialquil-eter de la 2-amino-7-hidroxitetralina.
EA200400847A1 (ru) Производные имидазохинолина
EA200300997A1 (ru) Линейный олиголактатный сложный эфир
EA200101209A1 (ru) Новые производные бензола, способ их получения и фармацевтические композиции, содержащие их
EA200400470A1 (ru) Замещенные производные алкиламинопиридазинона, способ их получения и содержащие их фармацевтические композиции
EA200300400A1 (ru) 17α-ФТОРАЛКИЛСТЕРОИДЫ, СПОСОБ ИХ ПОЛУЧЕНИЯ И СОДЕРЖАЩИЕ ЭТИ СОЕДИНЕНИЯ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ
EA200400756A1 (ru) Новые соединения бензотиазина и бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат

Legal Events

Date Code Title Description
HC1A Change in name of an applicant in a eurasian application
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY RU