EA200400192A1 - Фармацевтическая композиция для лечения заболеваний, характеризующихся снижением и/или нарушением когнитивных функций - Google Patents
Фармацевтическая композиция для лечения заболеваний, характеризующихся снижением и/или нарушением когнитивных функцийInfo
- Publication number
- EA200400192A1 EA200400192A1 EA200400192A EA200400192A EA200400192A1 EA 200400192 A1 EA200400192 A1 EA 200400192A1 EA 200400192 A EA200400192 A EA 200400192A EA 200400192 A EA200400192 A EA 200400192A EA 200400192 A1 EA200400192 A1 EA 200400192A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- pharmaceutical composition
- diseases
- decrease
- treatment
- cognitive functions
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 230000003920 cognitive function Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- RFQWRWCCNQNACG-HJYQBBATSA-N (e)-but-2-enedioic acid;n,n-dimethyl-2-[[(1r,3s,4r)-4,7,7-trimethyl-3-phenyl-3-bicyclo[2.2.1]heptanyl]oxy]ethanamine Chemical compound OC(=O)\C=C\C(O)=O.C1([C@@]2([C@]3(C)CC[C@@H](C3(C)C)C2)OCCN(C)C)=CC=CC=C1 RFQWRWCCNQNACG-HJYQBBATSA-N 0.000 abstract 1
- 208000023105 Huntington disease Diseases 0.000 abstract 1
- 208000006264 Korsakoff syndrome Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000003340 mental effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Настоящее изобретение относится к фармацевтической композиции, содержащей в качестве активного ингредиента соединение общей формулы (I), где R означает водород или метил, для лечения или профилактики заболеваний, характеризующихся либо снижением и/или нарушением когнитивных функций, либо умственной неполноценностью, сопровождающей другие заболевания, в частности к фармацевтической композиции для лечения болезни Паркинсона, синдрома Корсакова или болезни Хантингтона. В качестве соединения общей формулы (I) предпочтительней использовать (1R,2S,4R)-(-)-2-(2-диметиламиноэтокси)-2-фенил-1,7,7-триметилбицикло[2.2.1]гептанфумарат.Отчет о международном поиске был опубликован 2003.10.18.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0103017A HUP0103017A3 (en) | 2001-07-18 | 2001-07-18 | Pharmaceutical composition for the treatment of diseases caused by impairment of cognitive functions and its use |
| PCT/HU2002/000069 WO2003007926A2 (en) | 2001-07-18 | 2002-07-18 | Pharmaceutical composition comprising deramciclane for the treatment of the decline and/or damage of cognitive functions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200400192A1 true EA200400192A1 (ru) | 2004-06-24 |
| EA006897B1 EA006897B1 (ru) | 2006-04-28 |
Family
ID=90001562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200400192A EA006897B1 (ru) | 2001-07-18 | 2002-07-18 | Фармацевтическая композиция для лечения заболеваний, характеризующихся снижением и/или нарушением когнитивных функций |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20040171696A1 (ru) |
| EP (1) | EP1408940B1 (ru) |
| JP (1) | JP2004537548A (ru) |
| KR (1) | KR20040017326A (ru) |
| CN (1) | CN1545410A (ru) |
| AT (1) | ATE408403T1 (ru) |
| CA (1) | CA2453834A1 (ru) |
| CZ (1) | CZ200460A3 (ru) |
| DE (1) | DE60228968D1 (ru) |
| EA (1) | EA006897B1 (ru) |
| HU (1) | HUP0103017A3 (ru) |
| IL (1) | IL159841A0 (ru) |
| PL (1) | PL365258A1 (ru) |
| RS (1) | RS4904A (ru) |
| SK (1) | SK312004A3 (ru) |
| UA (1) | UA78714C2 (ru) |
| WO (1) | WO2003007926A2 (ru) |
| ZA (1) | ZA200400481B (ru) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0301537A3 (en) * | 2003-06-03 | 2005-07-28 | Egis Gyogyszergyar Nyilvanosan | Deramcyclane fumarate tablets and process for producing them |
| HUP0301906A3 (en) * | 2003-06-23 | 2006-03-28 | Egis Gyogyszergyar Nyilvanosan | Use of bicyclo[2.2.1]heptane derivatives for producing of pharmaceutical compositions having neuroprotectiv activity |
| EP1500391A1 (en) * | 2003-07-24 | 2005-01-26 | Neuro3D | Therapeutic use of bicycloheptane derivatives |
| BRPI0418634A (pt) * | 2004-03-12 | 2007-05-29 | Egis Gyogyszergyar Nyrt | composição farmacêutica combinada para a inibição do declìnio das funções cognitivas |
| SK50812006A3 (sk) * | 2004-03-12 | 2007-03-01 | Egis Gy�gyszergy�r Nyrt. | Kombinácia deramciklanu a opioidov ako analgetík |
| KR101642113B1 (ko) | 2014-10-08 | 2016-07-25 | 원광대학교산학협력단 | 퇴행성 뇌질환을 예방, 개선 또는 치료하는 유황의 법제 방법 및 상기 방법으로 법제된 유황 |
| US11478467B2 (en) | 2017-05-04 | 2022-10-25 | Sreenivasarao Vepachedu | Targeted drug rescue with novel compositions, combinations, and methods thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU179164B (en) * | 1979-12-14 | 1982-08-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing cycloalkyl-ethers of alkanolamines |
| HU226061B1 (en) * | 1996-10-17 | 2008-04-28 | Egis Gyogyszergyar Nyilvanosan | 1,7,7-trimethyl-bicyclo[2.2.1]heptane derivative, pharmaceutical compositions containing the same and process for their preparation |
| HU227114B1 (en) * | 1999-05-11 | 2010-07-28 | Egis Gyogyszergyar Nyilvanosan | (1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same |
| US6335371B1 (en) * | 2000-11-28 | 2002-01-01 | Orion Corporation | Method for inducing cognition enhancement |
-
2001
- 2001-07-18 HU HU0103017A patent/HUP0103017A3/hu unknown
-
2002
- 2002-07-18 SK SK31-2004A patent/SK312004A3/sk not_active Application Discontinuation
- 2002-07-18 AT AT02745700T patent/ATE408403T1/de not_active IP Right Cessation
- 2002-07-18 IL IL15984102A patent/IL159841A0/xx unknown
- 2002-07-18 UA UA2004021167A patent/UA78714C2/uk unknown
- 2002-07-18 WO PCT/HU2002/000069 patent/WO2003007926A2/en active IP Right Grant
- 2002-07-18 EP EP02745700A patent/EP1408940B1/en not_active Expired - Lifetime
- 2002-07-18 KR KR10-2004-7000792A patent/KR20040017326A/ko active IP Right Grant
- 2002-07-18 PL PL02365258A patent/PL365258A1/xx not_active Application Discontinuation
- 2002-07-18 EA EA200400192A patent/EA006897B1/ru not_active IP Right Cessation
- 2002-07-18 US US10/483,808 patent/US20040171696A1/en not_active Abandoned
- 2002-07-18 DE DE60228968T patent/DE60228968D1/de not_active Expired - Fee Related
- 2002-07-18 CZ CZ200460A patent/CZ200460A3/cs unknown
- 2002-07-18 JP JP2003513535A patent/JP2004537548A/ja active Pending
- 2002-07-18 RS YU4904A patent/RS4904A/sr unknown
- 2002-07-18 CN CNA028163729A patent/CN1545410A/zh active Pending
- 2002-07-18 CA CA002453834A patent/CA2453834A1/en not_active Abandoned
-
2004
- 2004-01-22 ZA ZA200400481A patent/ZA200400481B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE408403T1 (de) | 2008-10-15 |
| DE60228968D1 (de) | 2008-10-30 |
| EA006897B1 (ru) | 2006-04-28 |
| KR20040017326A (ko) | 2004-02-26 |
| PL365258A1 (en) | 2004-12-27 |
| ZA200400481B (en) | 2005-01-24 |
| HUP0103017A3 (en) | 2004-05-28 |
| CN1545410A (zh) | 2004-11-10 |
| RS4904A (en) | 2006-10-27 |
| WO2003007926A3 (en) | 2003-09-18 |
| IL159841A0 (en) | 2004-06-20 |
| US20040171696A1 (en) | 2004-09-02 |
| JP2004537548A (ja) | 2004-12-16 |
| SK312004A3 (en) | 2004-06-08 |
| HUP0103017A2 (hu) | 2003-07-28 |
| UA78714C2 (en) | 2007-04-25 |
| EP1408940B1 (en) | 2008-09-17 |
| HUP0103017D0 (en) | 2001-10-28 |
| CA2453834A1 (en) | 2003-01-30 |
| EP1408940A2 (en) | 2004-04-21 |
| WO2003007926A2 (en) | 2003-01-30 |
| CZ200460A3 (cs) | 2004-05-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60238255D1 (de) | Azolsäure-derivate, allein oder kombiniert, zur behandlung von diabetes und dyslipidaemien; und zur behandlung von malignen erkrankungen | |
| EA200300776A1 (ru) | Производные фенэтаноламина для лечения респираторных заболеваний | |
| BRPI0409227B8 (pt) | "composto, composição farmacêutica, uso de um composto e processo para a preparação de um composto de fórmula (i)" | |
| SE0104334D0 (sv) | Therapeutic agents | |
| ATE381537T1 (de) | Formanilid-derivative als beta2-adrenorezeptor- agonisten | |
| CY1107850T1 (el) | Παραγωγα θειαδιαζολυλοπιπεραζiνης mε χρησιμοτητα στην αποτροπη ή στην αγωγη εναντι tου αλγους | |
| IL171977A (en) | Cyclic sulfonamide for inhibition of gamma-secretase, process for its preparation and a pharmaceutical composition comprising the same | |
| EA200300597A1 (ru) | Бифенилкарбоксамиды, полезные в качестве снижающих содержание липидов агентов | |
| BR0316723A (pt) | Derivados de anilinopirazol úteis para o tratamento de diabetes | |
| EA200400192A1 (ru) | Фармацевтическая композиция для лечения заболеваний, характеризующихся снижением и/или нарушением когнитивных функций | |
| DE60225143D1 (de) | Synergistische pharmazeutische zusammensetzungen zur behandlung bzw. prophylaxe von diabetes | |
| GEP20012389B (en) | Benzoxazinone Dopamine D4 Receptor Antagonists, Pharmaceutical Composition Containing the Same and Method for Treatment of Psychosis or Schizophrenia | |
| YU78302A (sh) | Derivat piridin-1-oksida i postupak za njegovu transformaciju u farmaceutski efikasna jedinjenja | |
| BRPI0409151A (pt) | uso de derivados de 10-hidróxi-10,11-diidrocarbamazepina para o tratamento de transtornos afetivos | |
| BR0306855A (pt) | Método para o tratamento de distúrbios cognitivos | |
| BR9909870A (pt) | Pirrolidinas como inibidores de neuraminidases | |
| ATE447953T1 (de) | Pharmazeutische zusammensetzungen zur behandlung von leishmaniasis | |
| BRPI0411245A (pt) | composto, composição farmacêutica, uso de um composto, e, métodos para tratamento ou profilaxia de vìrus oncogênicos e para tratamento ou profilaxia de condições ou distúrbios devidos a infecção por hpv | |
| DK1174131T3 (da) | Anvendelse af et middel til forbedring af astrocytfunktion til behandling af Parkinsons sygdom | |
| DE60238666D1 (de) | Cyclohexenon derivate zur behandlung der diabetischen neuropathie | |
| BRPI0407569A (pt) | uso de s-10-hidróxi-10, 11-diidro-carbamazepina para o tratamento de ansiendade e distúrbios bipolares | |
| EA200601666A1 (ru) | Комбинированная фармацевтическая композиция для ингибирования ухудшения когнитивных функций | |
| BR0116721A (pt) | Processo para a preparação de (±)-trans-4-p-fluorofenil-3-hidroximetil-1-metilpiperi dina | |
| EA200200987A1 (ru) | Лечение заболеваний, связанных с серотонинергической системой | |
| BR0309025A (pt) | Agentes antidiabéticos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH4A | Grant of a duplicate of a eurasian patent | ||
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ KZ KG MD TJ TM |
|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): BY RU |