DOP2014000258A - Tratamiento de la metástasis en el cerebro con una combinación de veliparib y una terapia con radiación en la totalidad del cerebro - Google Patents

Tratamiento de la metástasis en el cerebro con una combinación de veliparib y una terapia con radiación en la totalidad del cerebro

Info

Publication number
DOP2014000258A
DOP2014000258A DO2014000258A DO2014000258A DOP2014000258A DO P2014000258 A DOP2014000258 A DO P2014000258A DO 2014000258 A DO2014000258 A DO 2014000258A DO 2014000258 A DO2014000258 A DO 2014000258A DO P2014000258 A DOP2014000258 A DO P2014000258A
Authority
DO
Dominican Republic
Prior art keywords
brain
combination
radiation
metalasis
veliparib
Prior art date
Application number
DO2014000258A
Other languages
English (en)
Inventor
Vincent L Giranda
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48576528&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2014000258(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of DOP2014000258A publication Critical patent/DOP2014000258A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device

Abstract

Método para tratar las metástasis en el cerebro provenientes de un cáncer en las células pulmonares no pequeñas en un sujeto, que comprende administrarle al sujeto una cantidad eficaz de 2-[(2R)-2-metilpirrolidin-2-il]-1H-benzimidazol-4-carboxamida o de una sal farmacéuticamente aceptable de ésta, en combinación con una cantidad eficaz de radiación en la totalidad del cerebro.
DO2014000258A 2012-05-15 2014-11-14 Tratamiento de la metástasis en el cerebro con una combinación de veliparib y una terapia con radiación en la totalidad del cerebro DOP2014000258A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261647329P 2012-05-15 2012-05-15

Publications (1)

Publication Number Publication Date
DOP2014000258A true DOP2014000258A (es) 2015-01-15

Family

ID=48576528

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2014000258A DOP2014000258A (es) 2012-05-15 2014-11-14 Tratamiento de la metástasis en el cerebro con una combinación de veliparib y una terapia con radiación en la totalidad del cerebro

Country Status (18)

Country Link
US (1) US20130310625A1 (es)
EP (1) EP2849750A1 (es)
JP (1) JP2015521188A (es)
KR (1) KR20150017355A (es)
CN (1) CN104602688A (es)
AU (1) AU2013262906A1 (es)
BR (1) BR112014028618A2 (es)
CA (1) CA2873119A1 (es)
CL (1) CL2014003072A1 (es)
DO (1) DOP2014000258A (es)
HK (1) HK1207984A1 (es)
IL (1) IL235389A0 (es)
MX (1) MX2014013903A (es)
PH (1) PH12014502464A1 (es)
RU (1) RU2014150506A (es)
SG (1) SG11201407498RA (es)
TW (1) TW201400113A (es)
WO (1) WO2013173428A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017003304A (es) * 2014-09-16 2017-08-15 Abbvie Inc Veliparib en combinacion con carboplatino y paclitaxel para el tratamiento de cancer de pulmon de celulas no pequeñas en fumadores.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI375673B (en) 2005-04-11 2012-11-01 Abbott Lab 1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors
SI2338487T1 (sl) 2006-01-17 2014-01-31 Abbott Laboratories Kombinacijska terapija z inhibitorji PARP
EP2558866B1 (en) * 2010-04-15 2016-08-17 Tracon Pharmaceuticals, Inc. Potentiation of anti-cancer activity through combination therapy with ber pathway inhibitors

Also Published As

Publication number Publication date
PH12014502464A1 (en) 2014-12-22
TW201400113A (zh) 2014-01-01
CA2873119A1 (en) 2013-11-21
SG11201407498RA (en) 2014-12-30
CN104602688A (zh) 2015-05-06
MX2014013903A (es) 2015-01-16
KR20150017355A (ko) 2015-02-16
JP2015521188A (ja) 2015-07-27
AU2013262906A1 (en) 2014-11-20
IL235389A0 (en) 2014-12-31
HK1207984A1 (en) 2016-02-19
CL2014003072A1 (es) 2015-02-27
US20130310625A1 (en) 2013-11-21
BR112014028618A2 (pt) 2017-06-27
EP2849750A1 (en) 2015-03-25
RU2014150506A (ru) 2016-07-10
WO2013173428A1 (en) 2013-11-21

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