DOP2010000257A - Compuesto ( r) -n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-diamina y su uso como antipsicotico - Google Patents

Compuesto ( r) -n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-diamina y su uso como antipsicotico

Info

Publication number
DOP2010000257A
DOP2010000257A DO2010000257A DO2010000257A DOP2010000257A DO P2010000257 A DOP2010000257 A DO P2010000257A DO 2010000257 A DO2010000257 A DO 2010000257A DO 2010000257 A DO2010000257 A DO 2010000257A DO P2010000257 A DOP2010000257 A DO P2010000257A
Authority
DO
Dominican Republic
Prior art keywords
compound
diamine
tiazol
dihidro
etil
Prior art date
Application number
DO2010000257A
Other languages
English (en)
Inventor
William C Blackwell Iii
James Hulsizer
Jianwei Liu
Gary Steelman
Rebecca Urbanek
Dan Widzowski
Ye Wu
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of DOP2010000257A publication Critical patent/DOP2010000257A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Abstract

Esta invención se refiere al compuesto de Formula I y sus sales fármaceuticamente aceptables: (R)N* 6* -etil-6,7-dihidro-5H-indeno [5 ,6-d]tiazol-2,6-díamina. Esta invención también se refiere a Ios métodos para sintetizar, métodos para utilizar y a composiciones farmacéuticas que comprenden el compuesto de Fórmula I y sus sales.
DO2010000257A 2008-02-21 2010-08-20 Compuesto ( r) -n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-diamina y su uso como antipsicotico DOP2010000257A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3033208P 2008-02-21 2008-02-21

Publications (1)

Publication Number Publication Date
DOP2010000257A true DOP2010000257A (es) 2010-10-31

Family

ID=40985770

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2010000257A DOP2010000257A (es) 2008-02-21 2010-08-20 Compuesto ( r) -n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-diamina y su uso como antipsicotico

Country Status (24)

Country Link
US (1) US20090215841A1 (es)
EP (1) EP2254876A4 (es)
JP (1) JP2011512407A (es)
KR (1) KR20100122487A (es)
CN (1) CN101952266A (es)
AR (1) AR070618A1 (es)
AU (1) AU2009215920A1 (es)
BR (1) BRPI0907158A2 (es)
CA (1) CA2716215A1 (es)
CL (1) CL2009000392A1 (es)
CO (1) CO6300849A2 (es)
CR (1) CR11639A (es)
DO (1) DOP2010000257A (es)
EA (1) EA201001095A1 (es)
EC (1) ECSP10010412A (es)
IL (1) IL206817A0 (es)
MX (1) MX2010008923A (es)
NI (1) NI201000141A (es)
PE (1) PE20091566A1 (es)
SA (1) SA109300120B1 (es)
TW (1) TW200940516A (es)
UY (1) UY31668A1 (es)
WO (1) WO2009105026A1 (es)
ZA (1) ZA201004800B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6958797B2 (ja) * 2016-06-21 2021-11-02 浙江柏拉阿図医薬科技有限公司 Ｃ型肝炎ウイルス阻害剤およびその使用
CN109134600B (zh) * 2017-06-19 2021-07-20 杭州国谋生物科技有限公司 作为丙型肝炎抑制剂的烷基及杂环化合物及其在药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9802360D0 (sv) * 1998-07-01 1998-07-01 Wikstroem Hakan Vilhelm New 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins ((basic)-N-substituted and (basic)-N,N-disubstituted derivatives of 2,6-diamino-thiazolo(4,5-f)indan and 2,7-di-amino-thiazolo(4,5-g)tetralin
WO2005084205A2 (en) * 2004-02-27 2005-09-15 Teva Pharmaceutical Industries, Ltd. Diamino thiazoloindan derivatives and their use

Also Published As

Publication number Publication date
ZA201004800B (en) 2012-06-27
EP2254876A1 (en) 2010-12-01
PE20091566A1 (es) 2009-11-06
ECSP10010412A (es) 2010-09-30
CR11639A (es) 2010-10-05
SA109300120B1 (ar) 2011-10-08
EA201001095A1 (ru) 2011-04-29
MX2010008923A (es) 2010-09-07
NI201000141A (es) 2011-03-24
CO6300849A2 (es) 2011-07-21
CA2716215A1 (en) 2009-08-27
KR20100122487A (ko) 2010-11-22
BRPI0907158A2 (pt) 2015-07-07
EP2254876A4 (en) 2012-10-31
IL206817A0 (en) 2010-12-30
US20090215841A1 (en) 2009-08-27
WO2009105026A1 (en) 2009-08-27
CL2009000392A1 (es) 2010-09-24
CN101952266A (zh) 2011-01-19
UY31668A1 (es) 2009-09-30
AR070618A1 (es) 2010-04-21
TW200940516A (en) 2009-10-01
JP2011512407A (ja) 2011-04-21
AU2009215920A1 (en) 2009-08-27

Similar Documents

Publication Publication Date Title
CO6321282A2 (es) Derivados de piperidinilindol como inhibidores de aldosterona sintasa
CO6311079A2 (es) Derivados de aminodihidrotiazina como inhibidores de la enzima bace para el tratamiento de la enfermedad de alzheimer
GT200600117A (es) Nuevos compuestos farmaceuticos
CO6300954A2 (es) Derivados de tienopiridinonas como activadores de proteina quinasa activados por ampk
CR20140392A (es) Dihidropirazolonas sustituidas
GT200800242A (es) Derivados biciclicos como inhibidores de cetp
SV2010003598A (es) Derivados de tiazol usados como inhibidores de pi 3-cinasa
AR052404A1 (es) Hidratos y polimorfos de 4-(((7r)-8-ciclopentil-7-etil-5,6,7,8-tetrahidro-5-metil-6-oxo-2-pteridinil)amino)-3- metoxi-n-(1-metil-4-piperidinil)-benzamida, procedimiento para su preparacion y su uso como farmaco
ECSP109922A (es) Compuestos de pirazol y su uso como inhibidores raf
CL2008002295A1 (es) Compuestos derivados de tiazolida sustituidos con alquilsulfonilos; composicion farmaceutica; y uso para el tratamiento de la hepatitis c.
DOP2006000017A (es) Pirazolopiridinas y sales de las mismas, una composición farmaceútica que comprende dichos compuestos, un método para prepararlos y su uso
UY31922A (es) Compuestos
ECSP10010192A (es) 5-[(3,3,3-trifluoro-2-hidroxi-1-arilpropil)amino]-1h-quinolin-2-onas, un proceso para su producción y su uso como agentes antiinflamatorios
MY146671A (en) Tetrahydronaphthaline derivatives, methods for the production and use thereof as anti-inflammatory agents
UY29358A1 (es) Tiazolidinonas, su preparacion y su uso como medicamento
BR112012009311A2 (pt) composto, composição farmacêutica, e, uso do composto
UY32744A (es) Derivados de 2-carboxamida-7-piperazinil-benzofurano 774
SV2008002512A (es) Derivados de aminoacidos ref. pc32769a
DOP2010000257A (es) Compuesto ( r) -n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-diamina y su uso como antipsicotico
ECSP11011150A (es) Derivados de arilciclopropilacetamida útiles como activadores de glucoquinasa
PA8666801A1 (es) Derivado de 5h-bensociclohepteno, procedimiento para su preparacion y su uso como antiinflamatorios
ECSP088650A (es) Compuestos de amido y su uso como productos farmaceuticos
CY1112118T1 (el) 3-ινδαζολυλ-4-πυριδυλισοθειαζολες
DOP2007000062A (es) Agentes antifúngicos
UY29858A1 (es) Derivados de la 1-amino-ftalazina sustituida, su preparación y su aplicación en terapéutica