DK728988A - Chelaterende forbindelser og anvendelse deraf - Google Patents

Chelaterende forbindelser og anvendelse deraf

Info

Publication number
DK728988A
DK728988A DK728988A DK728988A DK728988A DK 728988 A DK728988 A DK 728988A DK 728988 A DK728988 A DK 728988A DK 728988 A DK728988 A DK 728988A DK 728988 A DK728988 A DK 728988A
Authority
DK
Denmark
Prior art keywords
chelating compounds
chelating
compounds
Prior art date
Application number
DK728988A
Other languages
Danish (da)
English (en)
Other versions
DK728988D0 (da
Inventor
Hirohiko Yamauchi
Jun Takahashi
Sakae Okano
Shigemi Seri
Makoto Azuma
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Publication of DK728988D0 publication Critical patent/DK728988D0/da
Publication of DK728988A publication Critical patent/DK728988A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
DK728988A 1987-12-29 1988-12-29 Chelaterende forbindelser og anvendelse deraf DK728988A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP33403687 1987-12-29

Publications (2)

Publication Number Publication Date
DK728988D0 DK728988D0 (da) 1988-12-29
DK728988A true DK728988A (da) 1989-06-30

Family

ID=18272785

Family Applications (1)

Application Number Title Priority Date Filing Date
DK728988A DK728988A (da) 1987-12-29 1988-12-29 Chelaterende forbindelser og anvendelse deraf

Country Status (6)

Country Link
US (1) US5071636A (ko)
EP (1) EP0322876A3 (ko)
KR (1) KR890009861A (ko)
AU (1) AU610322B2 (ko)
CA (1) CA1305143C (ko)
DK (1) DK728988A (ko)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2655339B2 (fr) * 1989-04-19 1992-04-10 Medgenix Group Sa Composes et complexes utiles notamment en imagerie medicale.
US5262175A (en) * 1989-05-10 1993-11-16 Solanki Kishor K Stabilization of radiopharmaceutical compositions
DE69006698T2 (de) * 1989-12-12 1994-05-26 Amersham Int Plc Phenyldiaminodithiolderivate.
US5808091A (en) * 1991-10-29 1998-09-15 Bracco International B.V. Rhenium and technetium complexes containing a hypoxia localizing moiety
US5330737A (en) * 1991-12-06 1994-07-19 Mallinckrodt Medical, Inc. Nitrogen-sulfur ligands as opiate receptor drug mimics
CA2129036A1 (en) * 1992-02-06 1993-08-19 Mallinckrodt Inc. Ligands for improving metal chelate formation kinetics
US5310536A (en) * 1992-02-06 1994-05-10 Mallinckrodt Medical, Inc. Ligands for improving metal chelate formation kinetics
US5496533A (en) * 1992-07-31 1996-03-05 Australian Nuclear Science & Technology Organisation Rhenium complexes
EP0689463B1 (en) * 1993-03-12 2002-07-24 Mallinckrodt Inc. Imidazole based nitrogen-sulfur ligands useful in radiographic imaging agents
DE69421173T2 (de) * 1993-03-15 2000-01-20 Mallinckrodt Inc Neue stickstoff-schwefel-liganden auf der basis eines heterocyclus für die verwendung in werkstoffen für die radiographische bildgebung
US5608110A (en) * 1993-06-15 1997-03-04 Bracco International B.V. Heteroatom-bearing ligands and metal complexes thereof
US5690904A (en) * 1993-07-12 1997-11-25 Amersham International Plc Diagnostic radiopharmaceutical compounds (That)
US20030220233A1 (en) 1994-01-24 2003-11-27 Neorx Corporation Radiolabeled annexins
US5968477A (en) * 1994-01-24 1999-10-19 Neorx Corporation Radiolabeled annexin conjugates with hexose and a chelator
IL113610A0 (en) * 1994-06-03 1995-08-31 Immunomedics Inc A method of radiolabeling a protein, radiolabeled proteins prepared thereby and diagnostic kits containing the same
US5632969A (en) * 1994-10-13 1997-05-27 Merck & Co., Inc. N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
CA2166676C (en) * 1995-01-09 2007-05-01 Yasuhisa Fujibayashi Diagnostic agent for hypoxia or mitochondrial dysfunction comprising radioactive copper complex of dithiosemicarbazone derivative or diamine diol schiff base derivative
ES2264259T3 (es) * 1999-04-30 2006-12-16 Trustees Of The University Of Pennsylvania Agentes de obtencion de imagenes por spect (tomografia por emision de foton unico) para transportador de serotonina.
US6921840B1 (en) 1999-04-30 2005-07-26 The Trustees Of The University Of Pennsylvania SPECT imaging agents for serotonin transporters
WO2006029303A2 (en) * 2004-09-09 2006-03-16 The Trustees Of The University Of Pennsylvania Diphenyl ether derivatives and their use for imaging serotonin transporters
US11495560B2 (en) * 2015-08-10 2022-11-08 X Display Company Technology Limited Chiplets with connection posts
US10468363B2 (en) 2015-08-10 2019-11-05 X-Celeprint Limited Chiplets with connection posts

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444690A (en) * 1982-02-25 1984-04-24 University Patents, Inc. Technetium chelates
US4673562A (en) * 1983-08-19 1987-06-16 The Children's Medical Center Corporation Bisamide bisthiol compounds useful for making technetium radiodiagnostic renal agents
US4638051A (en) * 1984-04-30 1987-01-20 The Johns Hopkins University Brain imaging radiopharmaceuticals
WO1986000897A1 (en) * 1984-07-19 1986-02-13 University Of Florida Novel radiopharmaceuticals and chelating agents useful in their preparation
EP0200211A1 (en) * 1985-05-01 1986-11-05 The Research Foundation Of State University Of New York Diagnostic radiopharmaceutical compounds
EP0250013B1 (en) * 1986-05-28 1990-05-09 MALLINCKRODT, INC.(a Missouri corporation) Technetium chelates to be used for determining the renal function
US4925650A (en) * 1988-11-16 1990-05-15 Mallinckrodt, Inc. Technetium -99m complex for examining the renal function

Also Published As

Publication number Publication date
KR890009861A (ko) 1989-08-04
DK728988D0 (da) 1988-12-29
EP0322876A2 (en) 1989-07-05
AU610322B2 (en) 1991-05-16
AU2755788A (en) 1989-07-13
EP0322876A3 (en) 1990-09-05
US5071636A (en) 1991-12-10
CA1305143C (en) 1992-07-14

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment