DK592284A - Toxoid, vaccinepraeparat indeholdende det og fremgangsmaade til fremstilling af det - Google Patents

Toxoid, vaccinepraeparat indeholdende det og fremgangsmaade til fremstilling af det Download PDF

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Publication number
DK592284A
DK592284A DK592284A DK592284A DK592284A DK 592284 A DK592284 A DK 592284A DK 592284 A DK592284 A DK 592284A DK 592284 A DK592284 A DK 592284A DK 592284 A DK592284 A DK 592284A
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DK
Denmark
Prior art keywords
toxoid
preparing
procedure
preparation containing
vaccine preparation
Prior art date
Application number
DK592284A
Other languages
English (en)
Other versions
DK592284D0 (da
Inventor
Michael Victor Hayes
Stephen Harford
Gordon William Ross
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DK592284D0 publication Critical patent/DK592284D0/da
Publication of DK592284A publication Critical patent/DK592284A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK592284A 1983-12-12 1984-12-11 Toxoid, vaccinepraeparat indeholdende det og fremgangsmaade til fremstilling af det DK592284A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838333131A GB8333131D0 (en) 1983-12-12 1983-12-12 Microbiological process

Publications (2)

Publication Number Publication Date
DK592284D0 DK592284D0 (da) 1984-12-11
DK592284A true DK592284A (da) 1985-06-13

Family

ID=10553190

Family Applications (1)

Application Number Title Priority Date Filing Date
DK592284A DK592284A (da) 1983-12-12 1984-12-11 Toxoid, vaccinepraeparat indeholdende det og fremgangsmaade til fremstilling af det

Country Status (6)

Country Link
EP (1) EP0145486A3 (da)
JP (1) JPS615097A (da)
AU (1) AU3644784A (da)
DK (1) DK592284A (da)
GB (1) GB8333131D0 (da)
ZA (1) ZA849682B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340372C (en) * 1984-07-09 1999-02-02 John D. Clements Production of e. coli lt-b enterotoxin subunit
DE3781541T2 (de) * 1986-12-23 1993-05-06 Univ Leland Stanford Junior Modifiziertes pertussistoxin.
IT1253009B (it) * 1991-12-31 1995-07-10 Sclavo Ricerca S R L Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini
GB9622660D0 (en) * 1996-10-31 1997-01-08 Biocine Spa Immunogenic detoxified mutant toxin
US6818222B1 (en) 1997-03-21 2004-11-16 Chiron Corporation Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
US7115730B1 (en) 1999-04-27 2006-10-03 Chiron Srl Immunogenic detoxified mutant E. coli LT-A-toxin
TWI506135B (zh) * 2012-10-24 2015-11-01 突變型大腸桿菌忌熱毒素、其製備方法、增加免疫反應之佐劑及疫苗

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4264737A (en) * 1978-09-21 1981-04-28 President And Fellows Of Harvard College Method of making genetically stable mutants of vibrio cholerae
US4328209A (en) * 1979-04-11 1982-05-04 Board Of Regents, The University Of Texas System Cholera vaccine
JPS58146596A (ja) * 1982-02-25 1983-09-01 Takeda Chem Ind Ltd 組換えｄｎａ、それで形質転換させた微生物およびそれらの用途
US4666837A (en) * 1982-05-24 1987-05-19 Smithkline-Rit DNA sequences, recombinant DNA molecules and processes for producing the A and B subunits of cholera toxin and preparations containing so-obtained subunit or subunits

Also Published As

Publication number Publication date
EP0145486A2 (en) 1985-06-19
EP0145486A3 (en) 1986-10-08
AU3644784A (en) 1985-07-04
DK592284D0 (da) 1984-12-11
ZA849682B (en) 1986-08-27
GB8333131D0 (en) 1984-01-18
JPS615097A (ja) 1986-01-10

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