DK584483A - Middel paa basis af heparin eller et heparin-fragment til inhibering af angiogenese hos pattedyr - Google Patents

Middel paa basis af heparin eller et heparin-fragment til inhibering af angiogenese hos pattedyr Download PDF

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Publication number
DK584483A
DK584483A DK584483A DK584483A DK584483A DK 584483 A DK584483 A DK 584483A DK 584483 A DK584483 A DK 584483A DK 584483 A DK584483 A DK 584483A DK 584483 A DK584483 A DK 584483A
Authority
DK
Denmark
Prior art keywords
heparin
angiogenes
mammals
inhibiting
fragment
Prior art date
Application number
DK584483A
Other languages
English (en)
Other versions
DK584483D0 (da
DK168876B1 (da
Inventor
Moses Judah Folkman
Stephanie Taylor
Robert Samuel Langer
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of DK584483D0 publication Critical patent/DK584483D0/da
Publication of DK584483A publication Critical patent/DK584483A/da
Application granted granted Critical
Publication of DK168876B1 publication Critical patent/DK168876B1/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK584483A 1982-12-20 1983-12-19 Middel, der kan administreres oralt eller subcutant, til inhibering af angiogenese hos pattedyr samt fremgangsmåde til fremstilling af et sådant middel DK168876B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US45143182A 1982-12-20 1982-12-20
US45143182 1982-12-20
US55917583A 1983-12-07 1983-12-07
US55917583 1983-12-07

Publications (3)

Publication Number Publication Date
DK584483D0 DK584483D0 (da) 1983-12-19
DK584483A true DK584483A (da) 1984-06-21
DK168876B1 DK168876B1 (da) 1994-07-04

Family

ID=27036374

Family Applications (1)

Application Number Title Priority Date Filing Date
DK584483A DK168876B1 (da) 1982-12-20 1983-12-19 Middel, der kan administreres oralt eller subcutant, til inhibering af angiogenese hos pattedyr samt fremgangsmåde til fremstilling af et sådant middel

Country Status (5)

Country Link
EP (1) EP0114589B1 (da)
AU (1) AU555290B2 (da)
CA (1) CA1226816A (da)
DE (1) DE3373782D1 (da)
DK (1) DK168876B1 (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2553287B1 (fr) * 1983-10-18 1986-09-12 Choay Sa Compositions a base de mucopolysaccharides ou d'oligosaccharides, notamment a base de fractions ou fragments d'heparine, appropriees au traitement de desordres de la proliferation cellulaire
DE3432661A1 (de) * 1984-09-05 1986-03-06 Albert Prof. Dr. 6907 Nußloch Landsberger Carcinom-therapeutikum
US4771042A (en) * 1985-11-25 1988-09-13 The Upjohn Company Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments
ATE82126T1 (de) * 1986-04-04 1992-11-15 Angiogenics Ltd Zubereitung zum stoppen von angiogenese und einem kapillar-, zellen- oder membranleck.
US4966890A (en) * 1986-04-04 1990-10-30 Angiogenics, Ltd. Method and composition for arresting angiogenesis and capillary, cell or membrane leakage
US4820693A (en) * 1986-05-22 1989-04-11 Angiogenics, Ltd. Method and composition for arresting angiogenesis and capillary, cell or membrane leakage
FR2597484B1 (fr) * 1986-04-17 1988-12-23 Sanofi Sa Glycosaminoglycanes de type heparine ou heparane-sulfate dotes d'une activite sur la division et la differentiation cellulaires, leur preparation et leurs applications therapeutiques.
IE61758B1 (en) * 1986-05-23 1994-11-30 Daiichi Seiyaku Co Use of a sulfated polysaccharide
IL79255A0 (en) * 1986-06-26 1986-09-30 Hadassah Med Org Composition for metastasis prevention
US5206223A (en) * 1986-06-26 1993-04-27 Yeda Research And Development Co. Ltd. Method for inhibiting heparanase activity
IL85145A (en) * 1987-01-23 1994-08-26 Univ Australian Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity
US5541166A (en) * 1987-01-23 1996-07-30 The Australian National University Sulphated polysaccharides having anti-metastatic and/or anti-inflammatory activity
US5668116A (en) * 1987-03-19 1997-09-16 Anthropharm Pty. Limited Anti-inflammatory compounds and compositions
AU604542B2 (en) * 1987-03-19 1990-12-20 Arthropharm Pty Ltd Polysulphated polysaccharide complexes
JPH03502105A (ja) * 1988-11-01 1991-05-16 チルドレンズ メヂカル センター コーポレイション 抗血栓性ステロイド
US6090794A (en) * 1990-04-19 2000-07-18 The General Hospital Corporation Inhibition of neurofibrosarcoma growth and angiogenesis
US5733892A (en) * 1990-07-24 1998-03-31 Seikagaku Corporation Metastasis inhibitor composition comprising a phospholipid-linked glycosaminoglycan and method for inhibiting metastasis employing the same
CA2067211C (en) * 1990-07-24 2004-06-15 Katsukiyo Sakurai Phospholipid- or lipid-linked glycosaminoglycan, process for producing the same and metastasis inhibitor
US5514667A (en) * 1990-11-05 1996-05-07 Arthropharm Pty. Limited Method for topical treatment of herpes infections
KR100235782B1 (ko) * 1991-05-02 1999-12-15 파울리나 벤-아미 병리학적 과정의 예방 또는 치료를 위한 성분물
US6750207B1 (en) 1992-05-01 2004-06-15 Yeda Research And Development Co. Ltd. Compositions for the regulation of cytokine activity
US5861382A (en) * 1992-05-01 1999-01-19 Yeda Research And Development Co. Ltd. Methods for regulation of active TNF-α
AU3968597A (en) 1996-08-02 1998-02-25 Children's Medical Center Corporation Method of regulating the female reproductive system through angiogenesis inhibitors
US7056504B1 (en) 1998-08-27 2006-06-06 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase I and II
AU4351201A (en) 2000-03-08 2001-09-17 Massachusetts Inst Technology Heparinase iii and uses thereof
US6969705B2 (en) 2000-07-21 2005-11-29 Aventis Pharma S.A. Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
DE10141749A1 (de) * 2000-08-29 2002-03-14 Max Delbrueck Centrum Mittel zur Beeinflussung der Angiogenese
CA2423469A1 (en) 2000-10-18 2002-04-25 Massachusetts Institute Of Technology Methods and products related to pulmonary delivery of polysaccharides
US7285536B2 (en) 2001-12-05 2007-10-23 Yeda Research And Development Co., Ltd. Anti-cancer therapeutic compounds
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
US7956046B2 (en) 2003-07-24 2011-06-07 Aventis Pharma S.A. Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them
WO2005082376A1 (en) * 2004-02-26 2005-09-09 Advanced Ocular Systems Limited Tetracycline derivatives for the treatment of ocular pathologies
NZ589444A (en) 2008-05-28 2013-03-28 Validus Biopharma Inc NON-HORMONAL STEROID MODULATORS OF NF-Kappa B FOR TREATMENT OF DISEASE
EP2556083A4 (en) 2010-04-05 2013-12-04 Validus Biopharma Inc NONHORMONAL STEROID MODULATORS OF NF-KAPPA-B FOR DISEASE TREATMENT
US10034921B2 (en) 2013-02-13 2018-07-31 Laboratoire Français Du Fractionnement Et Des Biotechnologies Proteins with modified glycosylation and methods of production thereof
WO2017004205A1 (en) 2015-06-29 2017-01-05 Reveragen Biopharma, Inc. NON-HORMONAL STEROID MODULATORS OF NF-κB FOR TREATMENT OF DISEASE
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Also Published As

Publication number Publication date
EP0114589A1 (en) 1984-08-01
CA1226816A (en) 1987-09-15
EP0114589B1 (en) 1987-09-23
DK584483D0 (da) 1983-12-19
AU555290B2 (en) 1986-09-18
AU2258283A (en) 1984-06-28
DE3373782D1 (en) 1987-10-29
DK168876B1 (da) 1994-07-04

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