DK489986A - Cardiotoniske aroylthiazoloner - Google Patents

Cardiotoniske aroylthiazoloner Download PDF

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Publication number
DK489986A
DK489986A DK489986A DK489986A DK489986A DK 489986 A DK489986 A DK 489986A DK 489986 A DK489986 A DK 489986A DK 489986 A DK489986 A DK 489986A DK 489986 A DK489986 A DK 489986A
Authority
DK
Denmark
Prior art keywords
aroylthiazolones
cardiotonic
cardiotonic aroylthiazolones
Prior art date
Application number
DK489986A
Other languages
English (en)
Other versions
DK489986D0 (da
Inventor
J Martin Grisar
Richard C Dage
Richard A Schnettler
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK489986D0 publication Critical patent/DK489986D0/da
Publication of DK489986A publication Critical patent/DK489986A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK489986A 1985-10-15 1986-10-14 Cardiotoniske aroylthiazoloner DK489986A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78722685A 1985-10-15 1985-10-15

Publications (2)

Publication Number Publication Date
DK489986D0 DK489986D0 (da) 1986-10-14
DK489986A true DK489986A (da) 1987-04-16

Family

ID=25140799

Family Applications (1)

Application Number Title Priority Date Filing Date
DK489986A DK489986A (da) 1985-10-15 1986-10-14 Cardiotoniske aroylthiazoloner

Country Status (13)

Country Link
EP (1) EP0219112A3 (da)
JP (1) JPS6287579A (da)
KR (1) KR900000965B1 (da)
CN (1) CN86107178A (da)
AU (1) AU593289B2 (da)
CA (1) CA1266268A (da)
DK (1) DK489986A (da)
HU (1) HU196774B (da)
NO (1) NO168473C (da)
NZ (1) NZ217897A (da)
PH (1) PH23175A (da)
PT (1) PT83528B (da)
ZA (1) ZA867750B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4866182A (en) * 1988-02-18 1989-09-12 Merrell Dow Pharmaceuticals Inc. Cardiotonic alkanoyl and aroyl oxazolones
AU5628700A (en) * 1999-06-21 2001-01-09 Edson X. Albuquerque Thienylhydrazon with digitalis-like properties (positive inotropic effects)
US7091238B1 (en) 1999-06-21 2006-08-15 University Of Maryland Thienylhydrazon with digitalis-like properties (positive inotropic effects)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2249091B1 (da) * 1973-10-25 1978-11-17 Roussel Uclaf
US4649146A (en) * 1983-01-31 1987-03-10 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivatives and pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
CN86107178A (zh) 1987-07-15
HUT45034A (en) 1988-05-30
NO864087L (no) 1987-04-21
KR870004008A (ko) 1987-05-06
PH23175A (en) 1989-05-19
JPS6287579A (ja) 1987-04-22
EP0219112A2 (en) 1987-04-22
DK489986D0 (da) 1986-10-14
KR900000965B1 (ko) 1990-02-23
HU196774B (en) 1989-01-30
EP0219112A3 (en) 1988-03-23
PT83528A (en) 1986-11-01
CA1266268C (en) 1990-02-27
CA1266268A (en) 1990-02-27
ZA867750B (en) 1987-06-24
AU593289B2 (en) 1990-02-08
NZ217897A (en) 1989-04-26
PT83528B (pt) 1989-02-28
AU6384486A (en) 1987-04-16
NO864087D0 (no) 1986-10-14
NO168473B (no) 1991-11-18
NO168473C (no) 1992-02-26

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment