DK453684A - Pyridinderivater til medicinsk anvendelse og farmaceutiske praeparater indeholdende pyridinderivater - Google Patents

Pyridinderivater til medicinsk anvendelse og farmaceutiske praeparater indeholdende pyridinderivater Download PDF

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Publication number
DK453684A
DK453684A DK453684A DK453684A DK453684A DK 453684 A DK453684 A DK 453684A DK 453684 A DK453684 A DK 453684A DK 453684 A DK453684 A DK 453684A DK 453684 A DK453684 A DK 453684A
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DK
Denmark
Prior art keywords
pyridine derivatives
pharmaceutical preparations
medical use
preparations containing
containing pyridine
Prior art date
Application number
DK453684A
Other languages
English (en)
Other versions
DK453684D0 (da
DK158349B (da
DK158349C (da
Inventor
Robert Charles Hider
George Kontoghiorghes
Jack Silver
Michael Arthur Stockham
Original Assignee
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Res Dev filed Critical Nat Res Dev
Publication of DK453684D0 publication Critical patent/DK453684D0/da
Publication of DK453684A publication Critical patent/DK453684A/da
Publication of DK158349B publication Critical patent/DK158349B/da
Application granted granted Critical
Publication of DK158349C publication Critical patent/DK158349C/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40Oxygen atoms attached in positions 3 and 4, e.g. maltol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02Iron compounds
    • C07F15/025Iron compounds without a metal-carbon linkage

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK453684A 1983-09-23 1984-09-21 Ferrikomplekser af hydroxypyridinforbindelser samt farmaceutiske praeparater indeholdende saadanne komplekser DK158349C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8325494 1983-09-23
GB838325494A GB8325494D0 (en) 1983-09-23 1983-09-23 Pharmaceutical compositions

Publications (4)

Publication Number Publication Date
DK453684D0 DK453684D0 (da) 1984-09-21
DK453684A true DK453684A (da) 1985-03-24
DK158349B DK158349B (da) 1990-05-07
DK158349C DK158349C (da) 1990-10-15

Family

ID=10549200

Family Applications (1)

Application Number Title Priority Date Filing Date
DK453684A DK158349C (da) 1983-09-23 1984-09-21 Ferrikomplekser af hydroxypyridinforbindelser samt farmaceutiske praeparater indeholdende saadanne komplekser

Country Status (10)

Country Link
US (1) US4666927A (da)
EP (2) EP0138421B1 (da)
JP (2) JPH062739B2 (da)
CY (1) CY1516A (da)
DE (2) DE3486255T2 (da)
DK (1) DK158349C (da)
GB (2) GB8325494D0 (da)
GR (1) GR80445B (da)
SG (1) SG80989G (da)
ZA (1) ZA847408B (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308055D0 (en) * 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
GB8308054D0 (en) * 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
US4780238A (en) * 1983-08-25 1988-10-25 The United States Of America As Represented By The United States Department Of Energy Natural chelating agents for radionuclide decorporation
US5010191A (en) * 1985-08-19 1991-04-23 The Regents Of The University Of California Imaging agents for in vivo magnetic resonance and scintigraphic imaging
US4908371A (en) * 1987-11-10 1990-03-13 Ciba-Geigy Corporation Esterified hydroxy dihydropyridinones for treating diseases associated with trivalent metal ion overload
GB8910521D0 (en) * 1989-05-08 1989-06-21 Nat Res Dev The stabilization of organic compounds
US5393777A (en) * 1990-11-15 1995-02-28 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University Deferration using anguibactin siderophore
EP0498380A1 (de) * 1991-02-08 1992-08-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Komplexbildner
EP0648209A1 (de) * 1992-07-01 1995-04-19 Byk Gulden Lomberg Chemische Fabrik GmbH Kontrastmittel für die mr diagnostik
US5298525A (en) * 1992-11-23 1994-03-29 University Technologies International, Inc. Diabetes prevention and treatment
US5849587A (en) * 1995-06-09 1998-12-15 Cornell Research Foundation, Inc. Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells
ES2230564T3 (es) 1995-06-10 2005-05-01 Vitra Pharmaceuticals Ltd. Compuestos ferricos, composiciones, metodos de fabricacion de estos y sus utilizacioneds.
ES2221929T3 (es) * 1995-06-14 2005-01-16 The Regents Of The University Of California Agentes quelantes 3-hidroxi-2(1h)-piridinona.
US6140305A (en) 1996-04-04 2000-10-31 Bio-Rad Laboratories, Inc. Hereditary hemochromatosis gene products
US7026116B1 (en) * 1996-04-04 2006-04-11 Bio-Rad Laboratories, Inc. Polymorphisms in the region of the human hemochromatosis gene
US6849399B1 (en) 1996-05-23 2005-02-01 Bio-Rad Laboratories, Inc. Methods and compositions for diagnosis and treatment of iron misregulation diseases
ZA976421B (en) * 1996-07-22 1998-01-22 Boehringer Mannheim Italia New bis-platinum complexes with polyamine ligands as antitumor agents.
GB9625638D0 (en) * 1996-12-10 1997-01-29 Cenes Ltd Therapeutic antioxidants for alzheimer's diease
US6391852B1 (en) 1997-06-13 2002-05-21 Bio-Rad Laboratories, Inc. Methods and compositions for diagnosis and treatment of iron overload diseases and iron deficiency diseases
GB2345058A (en) * 1998-12-01 2000-06-28 Cerebrus Pharm Ltd Hydroxypyridone compounds useful in the treatment of oxidative damage to the central nervous system
US6767741B1 (en) 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
WO2002024196A1 (en) * 2000-09-19 2002-03-28 Vitra Pharmaceuticals Limited Iron compositions
US6846915B2 (en) 2001-08-13 2005-01-25 The Regents Of The University Of California Hydroxypyridonate and hydroxypyrimidinone chelating agents
GB0211500D0 (en) 2002-05-18 2002-06-26 Vitra Pharmaceuticals Ltd Method of forming iron hydroxypyrone compounds
US7595073B2 (en) * 2003-02-28 2009-09-29 Kraft Foods Global Brands Llc Use of siderophores and organic acids to retard lipid oxidation
GB0425555D0 (en) * 2004-11-19 2004-12-22 Glaxo Group Ltd Novel compounds
CA2659251C (en) * 2006-07-10 2016-06-14 The Regents Of The University Of California Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides
US9139456B2 (en) 2008-04-16 2015-09-22 The Curators Of The University Of Missouri Chelating compounds and immobilized tethered chelators
US9259670B2 (en) 2008-04-16 2016-02-16 The University Of Kentucky Research Foundation Flow-through filter to remove aluminum from medical solutions
US7932326B2 (en) * 2008-04-16 2011-04-26 The University Of Kentucky Research Foundation Chelating compounds and immobilized tethered chelators
US20100008864A1 (en) * 2008-07-10 2010-01-14 Andreas Meijer Aromatic multimers
EP2816038B8 (en) 2009-08-24 2019-12-25 Lumiphore, Inc. Hopo chelators
EP2516407A4 (en) * 2009-12-24 2013-06-12 Lumiphore Inc RADIOPHARMACEUTICAL COMPLEXES
US11453652B2 (en) 2013-03-15 2022-09-27 Lumiphore, Inc. Di-macrocycles
CN106928132B (zh) * 2017-02-23 2020-07-24 苏州大学 一种羟基吡啶酮配体及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3968118A (en) * 1968-08-31 1976-07-06 Hoechst Aktiengesellschaft Process for the manufacture of 1-hydroxy-2-pyridones
CA1049411A (en) * 1972-12-18 1979-02-27 Affiliated Medical Research N-substituted pyridone and general method for preparing pyridones
EP0094149B1 (en) * 1982-03-24 1986-09-10 National Research Development Corporation Pharmaceutical compositions containing a complex of iron with n-substituted 3-hydroxypyrid-2-one or -4-one derivatives
GB2118176B (en) * 1982-03-24 1985-12-04 Nat Res Dev Pharmaceutical compositions
GR78491B (da) * 1982-03-24 1984-09-27 Nat Res Dev

Also Published As

Publication number Publication date
GR80445B (en) 1985-01-23
JPH062740B2 (ja) 1994-01-12
DE3486255T2 (de) 1994-03-24
CY1516A (en) 1990-08-03
DE3486255D1 (de) 1994-01-20
GB8325494D0 (en) 1983-10-26
DE3483713D1 (de) 1991-01-17
DK453684D0 (da) 1984-09-21
DK158349B (da) 1990-05-07
EP0138421A2 (en) 1985-04-24
EP0357150A1 (en) 1990-03-07
US4666927A (en) 1987-05-19
EP0357150B1 (en) 1993-12-08
EP0138421B1 (en) 1990-12-05
GB8423799D0 (en) 1984-10-24
JPH062739B2 (ja) 1994-01-12
JPH02191254A (ja) 1990-07-27
SG80989G (en) 1990-07-06
DK158349C (da) 1990-10-15
GB2146989A (en) 1985-05-01
JPS6094965A (ja) 1985-05-28
ZA847408B (en) 1986-05-28
GB2146989B (en) 1987-02-18
EP0138421A3 (en) 1987-06-03

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