DK4153599T3 - Fremgangsmåde til at fremstille alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-carboxylat - Google Patents

Fremgangsmåde til at fremstille alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-carboxylat Download PDF

Info

Publication number
DK4153599T3
DK4153599T3 DK21726114.8T DK21726114T DK4153599T3 DK 4153599 T3 DK4153599 T3 DK 4153599T3 DK 21726114 T DK21726114 T DK 21726114T DK 4153599 T3 DK4153599 T3 DK 4153599T3
Authority
DK
Denmark
Prior art keywords
oxadiazolo
amino
methyl
procedure
pyridine carboxylate
Prior art date
Application number
DK21726114.8T
Other languages
English (en)
Inventor
Guenter Linz
Juergen Daeubler
Michael Pangerl
Rolf Schmid
Sarah Unger
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Application granted granted Critical
Publication of DK4153599T3 publication Critical patent/DK4153599T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK21726114.8T 2020-05-22 2021-05-18 Fremgangsmåde til at fremstille alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-carboxylat DK4153599T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20176112 2020-05-22
PCT/EP2021/063088 WO2021233882A1 (en) 2020-05-22 2021-05-18 Process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate

Publications (1)

Publication Number Publication Date
DK4153599T3 true DK4153599T3 (da) 2024-06-17

Family

ID=70804542

Family Applications (1)

Application Number Title Priority Date Filing Date
DK21726114.8T DK4153599T3 (da) 2020-05-22 2021-05-18 Fremgangsmåde til at fremstille alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-carboxylat

Country Status (7)

Country Link
US (1) US11518771B2 (da)
EP (1) EP4153599B1 (da)
JP (1) JP2023526351A (da)
CN (1) CN115884974A (da)
DK (1) DK4153599T3 (da)
TW (1) TW202208377A (da)
WO (1) WO2021233882A1 (da)

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004082383A1 (en) 2003-03-17 2004-09-30 Basf Aktiengesellschaft Use of triazolopyrimidines for combating nematode diseases of plants
WO2005019190A2 (en) * 2003-08-20 2005-03-03 Vertex Pharmaceuticals Incorporated (4 -amino -1,2, 5-oxadiazol-4-yl) -hetξroaromatic compounds useful as protein kinase inhibitors
CA2657660A1 (en) 2006-07-12 2008-01-17 Merck & Co., Inc. Substituted pyrazoles as ghrelin receptor antagonists
KR20150116465A (ko) 2007-02-15 2015-10-15 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 글루카곤/ｇｌｐ-1 수용체 공동-항진물질
EP3567035B1 (en) 2007-04-11 2022-06-01 CanBas Co., Ltd. N-substituted 2,5-dioxo-azoline compounds for use in the treatment of cancer
EP2152672A1 (en) 2007-05-24 2010-02-17 Bayer Schering Pharma Aktiengesellschaft Novel sulphoximine-substituted quinazoline and quinazoline derivatives as kinase inhibitors
DK2158214T3 (da) 2007-06-15 2011-12-05 Zealand Pharma As Glukagonanaloger
FR2934058B1 (fr) 2008-07-15 2010-09-24 Centre Nat Rech Scient Dispositif de projection interferometrique a trois ouvertures pour produire une tache constituee de structures fines
FR2933989B1 (fr) 2008-07-16 2013-03-08 Commissariat Energie Atomique Procede de purification de microorganismes presents dans des echantillons liquides
FR2933975B1 (fr) 2008-07-17 2011-02-18 Servier Lab Nouveau procede de preparation de benzocyclobutenes fonctionnalises,et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable.
CN102292347A (zh) 2008-12-15 2011-12-21 西兰制药公司 胰高血糖素类似物
US8389509B2 (en) * 2009-01-23 2013-03-05 Bristol-Myers Squibb Company Substituted pyrazole compounds
ME02220B (me) 2009-07-13 2016-02-20 Zealand Pharma As Analozi acilovanog glukagona
US20110078154A1 (en) 2009-09-28 2011-03-31 Accenture Global Services Gmbh Recruitment screening tool
UY33462A (es) 2010-06-23 2012-01-31 Zealand Pharma As Analogos de glucagon
BR112012033225A2 (pt) 2010-06-24 2017-06-20 Zealand Pharma As análogos do glucagon
BR112014015681A2 (pt) 2011-12-23 2019-09-24 Boehringer Ingelheim Int análogos de glucagon
JP6106179B2 (ja) 2012-02-24 2017-03-29 武田薬品工業株式会社 芳香環化合物
EP2863910B1 (en) 2012-06-20 2020-03-11 University Of Virginia Patent Foundation Compositions and methods for regulating glucose homeostasis and insulin action
TWI608013B (zh) 2012-09-17 2017-12-11 西蘭製藥公司 升糖素類似物
UA118034C2 (uk) 2013-11-14 2018-11-12 Елі Ліллі Енд Компані Заміщений піперидилетилпіримідин як інгібітор грелін-o-ацилтрансферази
US20170275249A1 (en) 2014-09-17 2017-09-28 The Regents Of The University Of California Small lipopeptidomimetic inhibitors of ghrelin o-acyl transferase
JP6615896B2 (ja) 2015-01-30 2019-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アルドステロン合成酵素阻害剤
AR104673A1 (es) 2015-04-15 2017-08-09 Lilly Co Eli Inhibidores de grelina o-aciltransferasa
AR104672A1 (es) 2015-04-15 2017-08-09 Lilly Co Eli Inhibidores de grelina o-aciltransferasa
ES2936400T3 (es) 2015-10-22 2023-03-16 Cavion Inc Métodos para tratar el síndrome Angelman
LT3494120T (lt) 2016-08-05 2021-05-25 Boehringer Ingelheim International Gmbh Oksadiazolopiridino dariniai, skirti naudoti kaip grelino o-aciltransferazės (goat) inhibitoriai
US10988487B2 (en) 2016-08-29 2021-04-27 Merck Sharp & Dohme Corp. Substituted n′-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
JP7083397B2 (ja) 2018-02-02 2022-06-10 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング グレリンｏ－アシルトランスフェラーゼ（ｇｏａｔ）阻害剤として使用するためのトリアゾロピリミジン誘導体
SG11202006300XA (en) 2018-02-02 2020-07-29 Boehringer Ingelheim Int Heterocyclyl-substituted oxadiazolopyridine derivatives for use as ghrelin o-acyl transferase (goat) inhibitors
KR20200116978A (ko) 2018-02-02 2020-10-13 베링거 인겔하임 인터내셔날 게엠베하 그렐린 o-아실 트랜스퍼라제(goat) 억제제로서의 벤질-치환된, (피리딘-3-일)메틸-치환된 또는 (피리딘-4-일)메틸-치환된 옥사디아졸로피리딘 유도체
EP3746449B1 (en) 2018-02-02 2022-03-30 Boehringer Ingelheim International GmbH Pyrazole- and indazole-substituted oxadiazolopyridine derivatives for use as ghrelin o-acyl transferase (goat) inhibitors

Also Published As

Publication number Publication date
WO2021233882A1 (en) 2021-11-25
TW202208377A (zh) 2022-03-01
EP4153599B1 (en) 2024-03-13
US20210363156A1 (en) 2021-11-25
US11518771B2 (en) 2022-12-06
EP4153599A1 (en) 2023-03-29
JP2023526351A (ja) 2023-06-21
CN115884974A (zh) 2023-03-31

Similar Documents

Publication Publication Date Title
DK3846904T3 (da) 5-morpholin-4-yl-pyrazolo[4,3-b]pyridinderivater
CY1124582T1 (el) Μεθοδος παραγωγης ενωσεων που εχουν δρασης αναστολης ιντεγκρασης hiv
LT3790877T (lt) Tetrahidro-imidazo[4,5-c]piridino dariniai kaip pd-l1 imunomoduliatoriai
DK3466955T3 (da) Fremgangsmåde til fremstilling af oxazol[4,5-b]pyridin og thiazol[4,5-b]pyridinderivater som irak4-hæmmere til behandling af cancer
MA53675A (fr) Composés substitués de pyrazolo[1,5-a]pyridine en tant qu'inhibiteurs de la kinase ret
DK3712152T3 (da) 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridin og 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepinderivater som janus kinase-inhibitorer
MA41251A (fr) Dérivés de thiéno[2,3-c]pyrrol-4-one comme inhibiteurs erk
EP3154970A4 (en) Pyrrolo[2,3-c]pyridines as imaging agents for neurofibrilary tangles
MY165215A (en) Pyridone derivatives
IL289877A (en) History of imidazopyridines and their use in cancer treatment
MA55751A (fr) Composés de 4h-pyrrolo[3,2-c]pyridin-4-one
WO2015142903A3 (en) Method of controlling lactate production with piperdine-dione derivatives
AU2012342891A8 (en) 3-Cyanoaryl-1H-pyrrolo[2.3-b]pyridine derivatives
MX2017007574A (es) Composicion.
CR20130041A (es) ISOXAZOLO[5,4-b]PIRIDINAS HERBICIDAS
MY178881A (en) Novel aqueous composition
WO2013152065A3 (en) 1,8-naphthyridin-2(1h)-one derivatives as cytomegalovirus inhibitors
MX2016005324A (es) Composiciones pesticidas y metodos relacionados.
DK3840832T3 (da) Imidazo[1,2-b]pyridaziner som trk-inhibitorer
SG10202110112TA (en) Novel imidazo[4,5-c]quinoline derivatives as lrrk2 inhibitors
IL308862A (en) Altered phenyl-1H-pyrrolo[3,2-c]pyridine histories
IL264780B (en) A method for producing 2-(3,6-dihalopyridin-2-yl)-3h-imidazolo[4,5-c]pyridine derivatives and similar compounds by reacting a 3h-imidazolo[4,5-c]pyridine derivative with a base Organometallic zinc-amine
MX354136B (es) Metodos para preparar 3-sustituido. 6-trifluorometil piridinas y metodos para la utilizacion de 6-triclorometil piridinas halogenadas.
IL280122A (en) Imidazo[2,1-B]pyridazine derivatives as TRK inhibitors
DK4153599T3 (da) Fremgangsmåde til at fremstille alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-carboxylat