DK382A - ANTIALLERGIC IMIDODISULPHAMIDS. - Google Patents

ANTIALLERGIC IMIDODISULPHAMIDS. Download PDF

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Publication number
DK382A
DK382A DK382A DK382A DK382A DK 382 A DK382 A DK 382A DK 382 A DK382 A DK 382A DK 382 A DK382 A DK 382A DK 382 A DK382 A DK 382A
Authority
DK
Denmark
Prior art keywords
imidodisulphamids
antiallergic
symptons
chlorosulfonyl
imide
Prior art date
Application number
DK382A
Other languages
Danish (da)
Inventor
Fadia Elfehail Ali
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of DK382A publication Critical patent/DK382A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/08—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B21/00—Nitrogen; Compounds thereof
    • C01B21/082—Compounds containing nitrogen and non-metals and optionally metals
    • C01B21/087—Compounds containing nitrogen and non-metals and optionally metals containing one or more hydrogen atoms
    • C01B21/093—Compounds containing nitrogen and non-metals and optionally metals containing one or more hydrogen atoms containing also one or more sulfur atoms
    • C01B21/0935—Imidodisulfonic acid; Nitrilotrisulfonic acid; Salts thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Imidodisulfamide derivatives useful in the treatment of allergic conditions are prepared by reaction of an appropriately substituted tetrahydroisoquinoline and bis-(chlorosulfonyl)imide in the presence of a non-nucleophilic organic base. Pharmaceutical compositions and methods of inhibiting the symptons of an allergic response are also disclosed.
DK382A 1981-01-05 1982-01-04 ANTIALLERGIC IMIDODISULPHAMIDS. DK382A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/222,478 US4385047A (en) 1981-01-05 1981-01-05 Antiallergic imidodisulfamides

Publications (1)

Publication Number Publication Date
DK382A true DK382A (en) 1982-07-06

Family

ID=22832388

Family Applications (1)

Application Number Title Priority Date Filing Date
DK382A DK382A (en) 1981-01-05 1982-01-04 ANTIALLERGIC IMIDODISULPHAMIDS.

Country Status (8)

Country Link
US (1) US4385047A (en)
EP (1) EP0055899B1 (en)
JP (1) JPS57134468A (en)
AT (1) ATE8137T1 (en)
DE (1) DE3164472D1 (en)
DK (1) DK382A (en)
GR (1) GR76984B (en)
IE (1) IE51884B1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1582884A (en) * 1977-05-19 1981-01-14 Beecham Group Ltd Clavulanic acid derivatives their preparation and use
ZA804670B (en) * 1979-08-03 1981-07-29 Beecham Group Ltd Derivatives of clavulanic acid, a process for their preparation and their use
EP0053893B1 (en) * 1980-12-09 1985-03-20 Beecham Group Plc Derivatives of clavulanic acid, their preparation and their use
US4562182A (en) * 1980-12-23 1985-12-31 Beecham Group P.L.C. Compounds containing beta-lactams
KR20180083896A (en) 2015-11-13 2018-07-23 론자 리미티드 Process for producing bis (fluorosulfonyl) -imide and salt thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE24763E (en) 1960-01-12 Ch ch j
US3062813A (en) * 1960-05-13 1962-11-06 Pennsalt Chemicals Corp Novel synthesis of sulfonamides
GB1384530A (en) * 1971-07-29 1975-02-19 Fisons Ltd Chromone derivatives
AT352135B (en) * 1975-07-30 1979-09-10 Thomae Gmbh Dr K Process for the preparation of new homophthalimides and their salts
JPS5484035A (en) * 1977-12-16 1979-07-04 Tanabe Seiyaku Co Ltd Anti-allergic agent
US4252818A (en) * 1979-08-02 1981-02-24 Merck & Co., Inc. Novel benzopyran derivatives
US4228170A (en) * 1979-08-30 1980-10-14 Smithkline Corporation 7- and/or 8-Sulfur substituted 1,2,3,4-tetrahydroisoquinoline compounds
US4315935A (en) * 1980-04-14 1982-02-16 Smithkline Corporation N,N'-Bis[substituted-1,2,3,4-tetrahydroisoquinolinolyl]disulfonylimides and antiallergic compositions and method of use
US4317826A (en) * 1980-05-27 1982-03-02 Smithkline Corporation N,N'-Bis[substituted-1,2,3,4 tetrahydroisoquinolyl]disulfonylimides and antiallergic compositions and method of use
US4296129A (en) * 1980-10-29 1981-10-20 Pfizer, Inc. (Carboxyacylamino)phenylalkenamides and esters thereof as SRS-A antagonists

Also Published As

Publication number Publication date
EP0055899A3 (en) 1982-09-08
US4385047A (en) 1983-05-24
ATE8137T1 (en) 1984-07-15
EP0055899B1 (en) 1984-06-27
IE820002L (en) 1982-07-05
JPS57134468A (en) 1982-08-19
EP0055899A2 (en) 1982-07-14
DE3164472D1 (en) 1984-08-02
GR76984B (en) 1984-09-04
IE51884B1 (en) 1987-04-15

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Legal Events

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AHS Application shelved for other reasons than non-payment