DK374085A - Tryptamin-derivater, deres fremstilling og anvendelse som laegemidler - Google Patents

Tryptamin-derivater, deres fremstilling og anvendelse som laegemidler Download PDF

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Publication number
DK374085A
DK374085A DK374085A DK374085A DK374085A DK 374085 A DK374085 A DK 374085A DK 374085 A DK374085 A DK 374085A DK 374085 A DK374085 A DK 374085A DK 374085 A DK374085 A DK 374085A
Authority
DK
Denmark
Prior art keywords
lower alkyl
phenyl
hydrogen
preparation
medicinal products
Prior art date
Application number
DK374085A
Other languages
English (en)
Other versions
DK374085D0 (da
Inventor
Thomas Glaser
Siegfried Raddatz
Joerg Traber
Allen George
Original Assignee
Troponwerke Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troponwerke Gmbh & Co Kg filed Critical Troponwerke Gmbh & Co Kg
Publication of DK374085D0 publication Critical patent/DK374085D0/da
Publication of DK374085A publication Critical patent/DK374085A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK374085A 1984-08-17 1985-08-16 Tryptamin-derivater, deres fremstilling og anvendelse som laegemidler DK374085A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843430284 DE3430284A1 (de) 1984-08-17 1984-08-17 Neue tryptamin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
DK374085D0 DK374085D0 (da) 1985-08-16
DK374085A true DK374085A (da) 1986-02-18

Family

ID=6243280

Family Applications (1)

Application Number Title Priority Date Filing Date
DK374085A DK374085A (da) 1984-08-17 1985-08-16 Tryptamin-derivater, deres fremstilling og anvendelse som laegemidler

Country Status (19)

Country Link
US (1) US4870085A (da)
EP (1) EP0171728B1 (da)
JP (1) JPS6169774A (da)
KR (1) KR910006637B1 (da)
CN (1) CN85101761A (da)
AT (1) ATE41930T1 (da)
AU (1) AU580321B2 (da)
DE (2) DE3430284A1 (da)
DK (1) DK374085A (da)
ES (1) ES8801824A1 (da)
FI (1) FI853134L (da)
GR (1) GR851986B (da)
HU (1) HU195208B (da)
IL (1) IL76088A (da)
NO (1) NO165343C (da)
NZ (1) NZ213104A (da)
PH (1) PH21048A (da)
PT (1) PT80954B (da)
ZA (1) ZA856227B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808581A (en) * 1986-03-17 1989-02-28 Glaxo Group Limited Imidazolyl- indolylpropanones as 5-HT3 receptor antagonists
DK134687A (da) * 1986-03-17 1987-09-18 Glaxo Group Ltd Indolderivater
US5162375A (en) * 1988-05-06 1992-11-10 Beecham Group P.L.C. Treatment of neuronal degeneration with 5HT1A agonists
GB8810748D0 (en) * 1988-05-06 1988-06-08 Beecham Wuelfing Gmbh & Co Kg Novel treatment
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
SI21560B (sl) * 1990-06-07 2005-04-30 Astrazeneca Ab 3,5-disubstituirani indolni derivati kot "5-HT1-podobni" receptorski agonisti
US5317103A (en) * 1991-01-15 1994-05-31 Merck Sharp & Dohme Limited Indole-substituted five-membered heteroaromatic compounds as 5-HT1 agonists
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
IL106445A (en) * 1992-07-30 1998-01-04 Merck Sharp & Dohme History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
DK139593D0 (da) * 1993-12-16 1993-12-16 Lundbeck & Co As H Compounds
CA2195107A1 (en) * 1994-08-02 1996-02-15 Richard Alexander Jelley Azetidine, pyrrolidine and piperidine derivatives
FR2733984B1 (fr) * 1995-05-10 1997-07-04 Rhone Poulenc Rorer Sa Derives de tryptamine, leur preparation et les medicaments les contenant
US5998462A (en) * 1996-12-16 1999-12-07 Allelix Biopharmaceuticals Inc. 5-alkyl indole compounds
US5856510A (en) * 1996-12-16 1999-01-05 Allelix Biopharmaceuticals Inc. 5-alkenyl and 5-alkynyl indole compounds
US6100291A (en) * 1998-03-16 2000-08-08 Allelix Biopharmaceuticals Inc. Pyrrolidine-indole compounds having 5-HT6 affinity
US6133287A (en) * 1998-03-24 2000-10-17 Allelix Biopharmaceuticals Inc. Piperidine-indole compounds having 5-HT6 affinity
EP1140074A1 (en) * 1998-12-23 2001-10-10 NPS Allelix Corp. Indole and indolizidine derivatives for the treatment of migraine
JP4119126B2 (ja) * 2000-04-28 2008-07-16 アカディア ファーマシューティカルズ，インコーポレーテッド ムスカリン性アゴニスト
CN103183629A (zh) * 2013-03-15 2013-07-03 张家港威胜生物医药有限公司 一种重要医药化工中间体5-溴吲哚高效合成工艺
CN104292145A (zh) * 2014-10-12 2015-01-21 湖南华腾制药有限公司 一种6-溴吲哚衍生物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3183235A (en) * 1961-06-27 1965-05-11 Sterling Drug Inc 1-[3-, 2-, and 1-indolyl-lower-alkanoyl] piperidines
US3821387A (en) * 1965-10-23 1974-06-28 Robins Co Inc A H The treatment of parkinsonism with 3-(omega-substituted alkyl)-indoles
US3907812A (en) * 1969-07-16 1975-09-23 Sumitomo Chemical Co Butyrophenone derivatives
US3732248A (en) * 1969-12-15 1973-05-08 Pfizer 3-substituted-1-phenyl indolinones
BE795457A (fr) * 1972-02-16 1973-08-16 Clin Midy Amines indoliques, leur preparation et leur application en therapeutiques
FR2506309A1 (fr) * 1981-05-22 1982-11-26 Pharmindustrie ((tetra- et hexahydro pyridyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments
FR2506310A1 (fr) * 1981-05-22 1982-11-26 Pharmindustrie ((alkyl- et alcenyl-3 piperidyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments

Also Published As

Publication number Publication date
IL76088A0 (en) 1985-12-31
EP0171728B1 (de) 1989-04-05
DE3430284A1 (de) 1986-02-27
PH21048A (en) 1987-07-03
IL76088A (en) 1990-03-19
EP0171728A1 (de) 1986-02-19
ES546091A0 (es) 1988-02-16
ZA856227B (en) 1986-04-30
JPS6169774A (ja) 1986-04-10
AU4597185A (en) 1986-02-20
FI853134A0 (fi) 1985-08-15
ATE41930T1 (de) 1989-04-15
US4870085A (en) 1989-09-26
CN85101761A (zh) 1987-02-04
NZ213104A (en) 1988-07-28
DK374085D0 (da) 1985-08-16
ES8801824A1 (es) 1988-02-16
KR870002124A (ko) 1987-03-30
FI853134L (fi) 1986-02-18
PT80954A (de) 1985-09-01
HUT39443A (en) 1986-09-29
NO165343C (no) 1991-01-30
NO165343B (no) 1990-10-22
GR851986B (da) 1985-12-10
NO853036L (no) 1986-02-18
PT80954B (pt) 1987-12-30
KR910006637B1 (ko) 1991-08-29
HU195208B (en) 1988-04-28
AU580321B2 (en) 1989-01-12
DE3569242D1 (en) 1989-05-11

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