DK3697887T3 - Perfusionsfremgangsmåder - Google Patents

Perfusionsfremgangsmåder Download PDF

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Publication number
DK3697887T3
DK3697887T3 DK18797333.4T DK18797333T DK3697887T3 DK 3697887 T3 DK3697887 T3 DK 3697887T3 DK 18797333 T DK18797333 T DK 18797333T DK 3697887 T3 DK3697887 T3 DK 3697887T3
Authority
DK
Denmark
Prior art keywords
perfusion procedures
perfusion
procedures
Prior art date
Application number
DK18797333.4T
Other languages
English (en)
Inventor
Matthew Angelini
Ashley Witmer
Anthony Debiase
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=64110133&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3697887(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Application granted granted Critical
Publication of DK3697887T3 publication Critical patent/DK3697887T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/14—Bioreactors or fermenters specially adapted for specific uses for producing enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/14—Incubators; Climatic chambers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/38—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of metabolites or enzymes in the cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M43/00—Combinations of bioreactors or fermenters with other apparatus
DK18797333.4T 2017-10-16 2018-10-15 Perfusionsfremgangsmåder DK3697887T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762572918P 2017-10-16 2017-10-16
PCT/US2018/055891 WO2019079188A1 (en) 2017-10-16 2018-10-15 PERFUSION BIOREACTOR AND METHODS OF USE THEREOF

Publications (1)

Publication Number Publication Date
DK3697887T3 true DK3697887T3 (da) 2022-05-02

Family

ID=64110133

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18797333.4T DK3697887T3 (da) 2017-10-16 2018-10-15 Perfusionsfremgangsmåder

Country Status (18)

Country Link
US (2) US11193103B2 (da)
EP (2) EP4039786A1 (da)
JP (2) JP7337784B2 (da)
KR (1) KR20200062236A (da)
CN (1) CN111212899A (da)
AR (1) AR113772A1 (da)
AU (1) AU2018350898A1 (da)
CA (1) CA3075679A1 (da)
DK (1) DK3697887T3 (da)
EA (1) EA202090740A1 (da)
ES (1) ES2919850T3 (da)
HU (1) HUE058924T2 (da)
IL (1) IL273150A (da)
MX (1) MX2020002851A (da)
PL (1) PL3697887T3 (da)
SG (1) SG11202002339XA (da)
TW (1) TWI827555B (da)
WO (1) WO2019079188A1 (da)

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MX2021002279A (es) 2018-08-27 2021-05-27 Regeneron Pharma Uso de espectroscopia raman en la purificacion corriente abajo.
CN113924355B (zh) * 2019-05-28 2024-04-02 上海药明生物技术有限公司 用于监测和自动控制灌流细胞培养的拉曼光谱集成灌流细胞培养***
MX2021014644A (es) * 2019-06-13 2022-04-06 Amgen Inc Control de perfusion basado en biomasa automatizado en la fabricacion de productos biologicos.
KR20220092948A (ko) * 2019-11-07 2022-07-04 메르크 파텐트 게엠베하 관류 세포 배양을 수행하기 위한 방법 및 시스템
EP4085126A1 (en) 2020-01-02 2022-11-09 F. Hoffmann-La Roche AG Single-use cell culture container with one or more in-situ online sensors
WO2021140002A1 (en) * 2020-01-07 2021-07-15 Cytiva Sweden Ab Systems and method for controlling fluid flow in bioreactors
KR102656244B1 (ko) 2020-10-26 2024-04-09 성균관대학교산학협력단 바이오리액터
AU2021392646A1 (en) * 2020-12-01 2023-06-22 The Brigham And Women's Hospital, Inc. Spectrometry systems, methods, and applications
KR102590857B1 (ko) * 2021-08-25 2023-10-19 재단법인 아산사회복지재단 세포 배양 장치
US20230323264A1 (en) * 2022-04-07 2023-10-12 Mirror Biologics, Inc. Artificial lymph node bioreactor
JP2024030410A (ja) 2022-08-24 2024-03-07 横河電機株式会社 細胞培養システム、及び細胞培養方法
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EP4039786A1 (en) * 2017-10-16 2022-08-10 Regeneron Pharmaceuticals, Inc. Perfusion bioreactor and related methods of use

Also Published As

Publication number Publication date
MX2020002851A (es) 2020-07-24
EP3697887B1 (en) 2022-04-06
BR112020005209A2 (pt) 2020-09-15
US20220056398A1 (en) 2022-02-24
JP7337784B2 (ja) 2023-09-04
CN111212899A (zh) 2020-05-29
EP4039786A1 (en) 2022-08-10
HUE058924T2 (hu) 2022-09-28
EA202090740A1 (ru) 2020-07-07
TW201934744A (zh) 2019-09-01
SG11202002339XA (en) 2020-04-29
AR113772A1 (es) 2020-06-10
US11193103B2 (en) 2021-12-07
KR20200062236A (ko) 2020-06-03
PL3697887T3 (pl) 2022-08-01
CA3075679A1 (en) 2019-04-25
WO2019079188A1 (en) 2019-04-25
EP3697887A1 (en) 2020-08-26
JP2020536521A (ja) 2020-12-17
JP2023156504A (ja) 2023-10-24
TWI827555B (zh) 2024-01-01
US20190153381A1 (en) 2019-05-23
US11965153B2 (en) 2024-04-23
ES2919850T3 (es) 2022-07-28
IL273150A (en) 2020-04-30
AU2018350898A1 (en) 2020-04-16

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