DK3653599T3 - Krystallinsk tapentadolphosphat - Google Patents

Krystallinsk tapentadolphosphat Download PDF

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Publication number
DK3653599T3
DK3653599T3 DK19208228.7T DK19208228T DK3653599T3 DK 3653599 T3 DK3653599 T3 DK 3653599T3 DK 19208228 T DK19208228 T DK 19208228T DK 3653599 T3 DK3653599 T3 DK 3653599T3
Authority
DK
Denmark
Prior art keywords
tapentadol phosphate
crystalline tapentadol
crystalline
phosphate
tapentadol
Prior art date
Application number
DK19208228.7T
Other languages
English (en)
Inventor
Wolfgang Albrecht
Richard Guserle
Jens Geier
Original Assignee
Ratiopharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm Gmbh filed Critical Ratiopharm Gmbh
Application granted granted Critical
Publication of DK3653599T3 publication Critical patent/DK3653599T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK19208228.7T 2016-04-19 2017-04-18 Krystallinsk tapentadolphosphat DK3653599T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP16166099 2016-04-19
EP16166101 2016-04-19
EP16170781 2016-05-23
EP16170780 2016-05-23
EP17716933.1A EP3445742B1 (en) 2016-04-19 2017-04-18 Crystalline tapentadol phosphate

Publications (1)

Publication Number Publication Date
DK3653599T3 true DK3653599T3 (da) 2023-01-30

Family

ID=58537027

Family Applications (3)

Application Number Title Priority Date Filing Date
DK20216224.4T DK3819287T3 (da) 2016-04-19 2017-04-18 Amorft tapentadolphosphat
DK19208228.7T DK3653599T3 (da) 2016-04-19 2017-04-18 Krystallinsk tapentadolphosphat
DK17716933.1T DK3445742T3 (da) 2016-04-19 2017-04-18 Krystallin tapentadolphosphat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK20216224.4T DK3819287T3 (da) 2016-04-19 2017-04-18 Amorft tapentadolphosphat

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK17716933.1T DK3445742T3 (da) 2016-04-19 2017-04-18 Krystallin tapentadolphosphat

Country Status (7)

Country Link
EP (3) EP3819287B1 (da)
DK (3) DK3819287T3 (da)
ES (3) ES2937740T3 (da)
HR (1) HRP20200029T1 (da)
PL (3) PL3445742T3 (da)
PT (1) PT3445742T (da)
WO (1) WO2017182438A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5968884B2 (ja) 2010-07-23 2016-08-10 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 3−(3−ジメチルアミノ−1−エチル−2−メチル−プロピル)−フェノールの塩または共結晶
ES2968510T3 (es) * 2020-03-02 2024-05-10 Gruenenthal Gmbh Forma de dosificación que proporciona liberación prolongada de sal de ácido fosfórico de Tapentadol
AU2020100441B4 (en) * 2020-03-02 2020-06-18 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
MX2022010780A (es) 2020-03-02 2022-09-26 Gruenenthal Gmbh Forma de dosificacion que proporciona liberacion prolongada de sal de acido fosforico de tapentadol.
AU2020100442B4 (en) * 2020-03-02 2020-06-18 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
EP3875079A1 (en) * 2020-03-02 2021-09-08 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
DE202020104285U1 (de) 2020-07-24 2020-12-18 Grünenthal GmbH Ethylcellulose-beschichtete Partikel enthaltend ein Salz aus Tapentadol und Phosphorsäure

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4426245A1 (de) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
SI1612203T1 (sl) 2004-06-28 2007-12-31 Gruenenthal Chemie Kristalne oblike (-)-(1R,2R)-3-(3-dimetilamino-1-etil-2-metilpropil)-fenol hidroklorida
ES2623413T3 (es) 2007-12-07 2017-07-11 Grünenthal GmbH Modificaciones cristalinas de (1R,2R)-3-(3-dimetilamino-1-etil-2-metilpropil)fenol
JP5968884B2 (ja) 2010-07-23 2016-08-10 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 3−(3−ジメチルアミノ−1−エチル−2−メチル−プロピル)−フェノールの塩または共結晶
WO2012051246A1 (en) 2010-10-12 2012-04-19 Ratiopharm Gmbh Tapentadol hydrobromide and crystalline forms thereof

Also Published As

Publication number Publication date
DK3819287T3 (da) 2023-12-18
PL3445742T3 (pl) 2020-05-18
EP3653599B1 (en) 2022-12-14
EP3819287B1 (en) 2023-09-20
EP3819287A1 (en) 2021-05-12
ES2937740T3 (es) 2023-03-30
EP3445742A1 (en) 2019-02-27
EP3445742B1 (en) 2019-11-13
PL3819287T3 (pl) 2024-03-11
HRP20200029T1 (hr) 2020-03-20
WO2017182438A1 (en) 2017-10-26
ES2966219T3 (es) 2024-04-19
ES2772806T3 (es) 2020-07-08
EP3653599A1 (en) 2020-05-20
DK3445742T3 (da) 2020-02-24
PT3445742T (pt) 2020-02-19
PL3653599T3 (pl) 2023-03-20

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