DK346181A - Fremgangsmaade til fremstilling af pyrazolobenzazepiner eller farmaceutisk acceptable salte deraf - Google Patents

Fremgangsmaade til fremstilling af pyrazolobenzazepiner eller farmaceutisk acceptable salte deraf

Info

Publication number
DK346181A
DK346181A DK346181A DK346181A DK346181A DK 346181 A DK346181 A DK 346181A DK 346181 A DK346181 A DK 346181A DK 346181 A DK346181 A DK 346181A DK 346181 A DK346181 A DK 346181A
Authority
DK
Denmark
Prior art keywords
pyrazolobenzazepins
procedure
preparation
acceptable salts
pharmaceutical acceptable
Prior art date
Application number
DK346181A
Other languages
English (en)
Inventor
R I Fryer
E J Trybulski
A Walser
G F Field
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK346181A publication Critical patent/DK346181A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/55Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/68Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
    • C07C63/72Polycyclic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK346181A 1980-08-05 1981-08-03 Fremgangsmaade til fremstilling af pyrazolobenzazepiner eller farmaceutisk acceptable salte deraf DK346181A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17555280A 1980-08-05 1980-08-05
US06/286,122 US4379765A (en) 1980-08-05 1981-07-23 Pyrazolobenzazepines

Publications (1)

Publication Number Publication Date
DK346181A true DK346181A (da) 1982-02-06

Family

ID=26871318

Family Applications (1)

Application Number Title Priority Date Filing Date
DK346181A DK346181A (da) 1980-08-05 1981-08-03 Fremgangsmaade til fremstilling af pyrazolobenzazepiner eller farmaceutisk acceptable salte deraf

Country Status (6)

Country Link
US (1) US4379765A (da)
EP (1) EP0045521B1 (da)
AU (1) AU545894B2 (da)
CA (1) CA1173031A (da)
DE (1) DE3164432D1 (da)
DK (1) DK346181A (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4379765A (en) * 1980-08-05 1983-04-12 Hoffmann-La Roche Inc. Pyrazolobenzazepines
US5166151A (en) * 1988-03-25 1992-11-24 Merck & Co., Inc. 2-Benzazepines with 5- and 6-membered heterocyclic rings, compositions and medical methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947585A (en) * 1974-06-03 1976-03-30 Ciba-Geigy Corporation Pyrazolobenzazepines
US4028381A (en) * 1975-05-05 1977-06-07 Ciba-Geigy Corporation Pyrazolobenzazepines
US4379765A (en) * 1980-08-05 1983-04-12 Hoffmann-La Roche Inc. Pyrazolobenzazepines

Also Published As

Publication number Publication date
EP0045521B1 (de) 1984-06-27
CA1173031A (en) 1984-08-21
AU7382481A (en) 1982-02-11
US4379765A (en) 1983-04-12
DE3164432D1 (en) 1984-08-02
EP0045521A1 (de) 1982-02-10
AU545894B2 (en) 1985-08-08

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment