DK3377511T3 - Azithromycinderivater med epithelial barriere-forbedrende egenskaber - Google Patents

Azithromycinderivater med epithelial barriere-forbedrende egenskaber Download PDF

Info

Publication number: DK3377511T3
Authority: DK; Denmark
Prior art keywords: epithelial barrier; enhancing properties; azithromycin derivatives; azithromycin; derivatives
Prior art date: 2015-11-19

Application number

DK16804720.7T

Other languages

English (en)

Inventor

Fredrik Lehmann

Fridrik Runar Gardarsson

Peter Teodorovic

Original Assignee

Epiendo Pharmaceuticals Ehf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-11-19

Filing date

2016-11-21

Publication date

2020-08-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55133040&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3377511(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2016-11-21 Application filed by Epiendo Pharmaceuticals Ehf filed Critical Epiendo Pharmaceuticals Ehf

2020-08-17 Application granted granted Critical

2020-08-17 Publication of DK3377511T3 publication Critical patent/DK3377511T3/da

Links

MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Materials For Medical Uses (AREA)

DK16804720.7T 2015-11-19 2016-11-21 Azithromycinderivater med epithelial barriere-forbedrende egenskaber DK3377511T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB1520419.1A GB201520419D0 (en)	2015-11-19	2015-11-19	Compounds
PCT/EP2016/078360 WO2017085329A1 (en)	2015-11-19	2016-11-21	Azithromycin derivatives with epithelial barrier enhancement properties

Publications (1)

Publication Number	Publication Date
DK3377511T3 true DK3377511T3 (da)	2020-08-17

Family

ID=55133040

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK16804720.7T DK3377511T3 (da)	2015-11-19	2016-11-21	Azithromycinderivater med epithelial barriere-forbedrende egenskaber

Country Status (19)

Country	Link
US (3)	US10723752B2 (da)
EP (2)	EP3708573A1 (da)
JP (2)	JP6849896B2 (da)
KR (1)	KR20180077282A (da)
CN (2)	CN114933620A (da)
CA (1)	CA3005088A1 (da)
CY (1)	CY1123418T1 (da)
DK (1)	DK3377511T3 (da)
ES (1)	ES2810703T3 (da)
GB (1)	GB201520419D0 (da)
HK (1)	HK1255270A1 (da)
HR (1)	HRP20201246T1 (da)
HU (1)	HUE050307T2 (da)
LT (1)	LT3377511T (da)
PL (1)	PL3377511T3 (da)
PT (1)	PT3377511T (da)
RS (1)	RS60698B1 (da)
SI (1)	SI3377511T1 (da)
WO (1)	WO2017085329A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB201520419D0 (en) *	2015-11-19	2016-01-06	Epi Endo Pharmaceuticals Ehf	Compounds
WO2023038852A1 (en) *	2021-09-07	2023-03-16	Zoetis Services Llc	Immunomodulating azalides
GB202404587D0 (en)	2024-03-28	2024-05-15	Epiendo Pharmaceuticals Ehf	Chemical forms

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3725385A (en)	1970-11-02	1973-04-03	Abbott Lab	Process for the demethylation of 3-amino macrolides
HRP20010018A2 (en) *	2001-01-09	2002-12-31	Pliva D D	Novel anti-inflammatory compounds
US20050171342A1 (en) *	2002-02-15	2005-08-04	Michael Burnet	Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
CN100577681C (zh)	2002-07-08	2010-01-06	葛兰素伊斯特拉齐瓦基森塔萨格勒布公司	用于治疗炎性疾病和病症的新化合物、组合物和方法
ITMI20022292A1 (it)	2002-10-29	2004-04-30	Zambon Spa	9a-azalidi ad attivita' antiinfiammatoria.
GB0310984D0 (en) *	2003-05-13	2003-06-18	Glaxo Group Ltd	Novel compounds
US7767797B1 (en) *	2004-09-30	2010-08-03	Synovo Gmbh	Macrocyclic compounds and methods of use thereof
EP1841776B1 (en) *	2005-01-13	2008-12-31	GlaxoSmithKline istrazivacki centar Zagreb d.o.o.	Decladinosyl-macrolides with anti-inflammatory activity
AU2006215315B2 (en) *	2005-01-13	2012-02-16	Glaxo Group Limited	Macrolides with anti-inflammatory activity
CN1837225A (zh) *	2005-08-23	2006-09-27	济南思创生物技术有限公司	阿奇霉素衍生物及其制法和药物应用
WO2007129646A1 (ja)	2006-05-01	2007-11-15	Taisho Pharmaceutical Co., Ltd.	マクロライド誘導体
CN101074251B (zh) *	2007-06-22	2011-06-15	山东大学	阿奇霉素4＂-氨甲酸酯衍生物、制备方法及其药物组合物
WO2009006403A2 (en) *	2007-06-29	2009-01-08	Georgia Tech Research Corporation	Non-peptide macrocyclic histone deacetylase (hdac) inhibitors and methods of making and using thereof
WO2010086351A1 (en) *	2009-01-30	2010-08-05	Glaxosmithkline Istrazivacki Centar Zagreb D.O.O.	3'-n-substituted 9-deoxo-9a-methyl-9a-aza-homoerythromycin having antimalarial activity
AU2011313862A1 (en)	2010-10-10	2013-05-30	Synovo Gmbh	Anti-inflammatory macrolides
GB201105633D0 (en) *	2011-04-01	2011-05-18	Norbrook Lab Ltd	Antibotic compounds
WO2013148874A1 (en) *	2012-03-27	2013-10-03	Burnet Michael W	Anti-inflammatory macrolides
AU2014252462A1 (en) *	2013-04-10	2015-10-01	Probiotic Pharmaceuticals Aps	Azithromycin antimicrobial derivatives with non-antibiotic pharmaceutical effect
GB201520419D0 (en)	2015-11-19	2016-01-06	Epi Endo Pharmaceuticals Ehf	Compounds

2015
- 2015-11-19 GB GBGB1520419.1A patent/GB201520419D0/en not_active Ceased
2016
- 2016-11-21 RS RS20200947A patent/RS60698B1/sr unknown
- 2016-11-21 JP JP2018526129A patent/JP6849896B2/ja active Active
- 2016-11-21 EP EP20172534.8A patent/EP3708573A1/en active Pending
- 2016-11-21 HU HUE16804720A patent/HUE050307T2/hu unknown
- 2016-11-21 CA CA3005088A patent/CA3005088A1/en active Pending
- 2016-11-21 ES ES16804720T patent/ES2810703T3/es active Active
- 2016-11-21 WO PCT/EP2016/078360 patent/WO2017085329A1/en active Application Filing
- 2016-11-21 CN CN202210535850.6A patent/CN114933620A/zh active Pending
- 2016-11-21 KR KR1020187017001A patent/KR20180077282A/ko not_active Application Discontinuation
- 2016-11-21 PT PT168047207T patent/PT3377511T/pt unknown
- 2016-11-21 EP EP16804720.7A patent/EP3377511B1/en active Active
- 2016-11-21 CN CN201680067151.6A patent/CN108290919B/zh active Active
- 2016-11-21 SI SI201630881T patent/SI3377511T1/sl unknown
- 2016-11-21 US US15/777,223 patent/US10723752B2/en active Active
- 2016-11-21 DK DK16804720.7T patent/DK3377511T3/da active
- 2016-11-21 LT LTEP16804720.7T patent/LT3377511T/lt unknown
- 2016-11-21 PL PL16804720T patent/PL3377511T3/pl unknown
2018
- 2018-11-12 HK HK18114428.3A patent/HK1255270A1/zh unknown
2020
- 2020-06-18 US US16/904,593 patent/US11236120B2/en active Active
- 2020-08-10 HR HRP20201246TT patent/HRP20201246T1/hr unknown
- 2020-08-12 CY CY20201100750T patent/CY1123418T1/el unknown
2021
- 2021-02-09 JP JP2021019109A patent/JP7256558B2/ja active Active
- 2021-12-15 US US17/551,223 patent/US20220106349A1/en active Pending

Also Published As

Publication number	Publication date
PT3377511T (pt)	2020-08-21
ES2810703T3 (es)	2021-03-09
HK1255270A1 (zh)	2019-08-09
CY1123418T1 (el)	2021-12-31
WO2017085329A1 (en)	2017-05-26
CN108290919B (zh)	2022-06-17
HRP20201246T1 (hr)	2020-11-13
CN114933620A (zh)	2022-08-23
US10723752B2 (en)	2020-07-28
JP2021073303A (ja)	2021-05-13
US11236120B2 (en)	2022-02-01
LT3377511T (lt)	2020-09-25
CN108290919A (zh)	2018-07-17
JP6849896B2 (ja)	2021-03-31
KR20180077282A (ko)	2018-07-06
JP2018534324A (ja)	2018-11-22
EP3708573A1 (en)	2020-09-16
CA3005088A1 (en)	2017-05-26
JP7256558B2 (ja)	2023-04-12
EP3377511A1 (en)	2018-09-26
US20200317710A1 (en)	2020-10-08
RS60698B1 (sr)	2020-09-30
US20180354981A1 (en)	2018-12-13
SI3377511T1 (sl)	2020-10-30
GB201520419D0 (en)	2016-01-06
EP3377511B1 (en)	2020-05-13
US20220106349A1 (en)	2022-04-07
PL3377511T3 (pl)	2020-11-16
HUE050307T2 (hu)	2020-11-30

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DE112016003063A5 (de)	2018-03-22	Verstellvorrichtung
DK3286193T3 (da)	2020-08-24	Indolderivater
FR3035464B1 (fr)	2017-04-14	Pendule- butee laterale -bimatiere
DE112017003625A5 (de)	2019-04-11	Difluorstilben-Derivate
IT201600077076A1 (it)	2018-01-22	Bicchiere
DK3303316T3 (da)	2020-04-27	Ethynylderivater
UA32689S (uk)	2016-08-10	Віконний косяк - утеплювач
SM201600001S1 (it)	2017-03-08	Ferma cerniera
UY4471S (es)	2016-11-30	Perfil
UY4470S (es)	2016-11-30	Perfil
UA30913S (uk)	2015-11-25	Міжкімнатні двері
FI11001U1 (fi)	2015-09-30	Ovi
UA30904S (uk)	2015-11-25	Міжкімнатні двері