DK330578A - Fremgangsmaade til fremstilling af dibenzo (b,f) thiepin-forbindelser - Google Patents

Fremgangsmaade til fremstilling af dibenzo (b,f) thiepin-forbindelser

Info

Publication number
DK330578A
DK330578A DK330578A DK330578A DK330578A DK 330578 A DK330578 A DK 330578A DK 330578 A DK330578 A DK 330578A DK 330578 A DK330578 A DK 330578A DK 330578 A DK330578 A DK 330578A
Authority
DK
Denmark
Prior art keywords
dibenzo
procedure
manufacture
thiepin
compounds
Prior art date
Application number
DK330578A
Other languages
English (en)
Inventor
J Rokach
C S Rooney
E J Cragoe
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK330578A publication Critical patent/DK330578A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D337/00Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02Seven-membered rings
    • C07D337/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14[b,f]-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00Thiols, sulfides, hydropolysulfides or polysulfides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
DK330578A 1977-07-26 1978-07-25 Fremgangsmaade til fremstilling af dibenzo (b,f) thiepin-forbindelser DK330578A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81919977A 1977-07-26 1977-07-26
US91721278A 1978-06-23 1978-06-23

Publications (1)

Publication Number Publication Date
DK330578A true DK330578A (da) 1979-01-27

Family

ID=27124337

Family Applications (1)

Application Number Title Priority Date Filing Date
DK330578A DK330578A (da) 1977-07-26 1978-07-25 Fremgangsmaade til fremstilling af dibenzo (b,f) thiepin-forbindelser

Country Status (16)

Country Link
EP (1) EP0011067B1 (da)
JP (1) JPS5444691A (da)
AR (2) AR226527A1 (da)
AU (1) AU517813B2 (da)
CA (1) CA1128048A (da)
DD (1) DD140746A5 (da)
DE (1) DE2861754D1 (da)
DK (1) DK330578A (da)
ES (5) ES471871A1 (da)
FI (1) FI782323A (da)
GR (1) GR67276B (da)
IE (1) IE47553B1 (da)
IT (1) IT1107485B (da)
NO (1) NO782539L (da)
PL (3) PL117756B1 (da)
PT (1) PT68303A (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536507A (en) * 1977-07-26 1985-08-20 Merck & Co., Inc. Prostaglandin antagonists
PT71280B (en) * 1979-06-01 1981-09-17 Merck & Co Inc Process for preparing prostaglandin antagonists
US4237160A (en) * 1979-11-27 1980-12-02 Merck Sharp & Dohme (I.A.) Corp. 3-Hydroxymethyldibenzo[b,f]thiepins as prostaglandin antagonists
EP0029587B1 (en) * 1979-11-27 1984-06-13 Merck Sharp & Dohme (I.A.) Corp. 3-hydroxymethyldibenzo(b,f)thiepins and dibenzo(b,f)thiepin-3-carboxaldehydes as prostaglandin antagonists, process for their preparation and pharmaceutical compositions
NO811187L (no) * 1980-11-24 1982-05-25 Merck & Co Inc Fremgangsmaate ved fremstilling av 7-fluor-dibenzo-(b,f)-thiepinderivater
US4535171A (en) * 1982-11-18 1985-08-13 Merck Frosst Canada, Inc. Dibenzo[b,f]thiepin-3-carboxaldehydes as prostaglandin antagonists
US4622403A (en) * 1983-10-11 1986-11-11 Merck Frosst Canada, Inc. 6-H dibenz[b,f]thiepin compounds
US4663347A (en) 1983-10-31 1987-05-05 Merck Frosst Canada, Inc. Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis
CA1309557C (en) 1985-06-18 1992-10-27 Robert N. Young Leukotriene antagonists
DE3786030T2 (de) 1986-03-27 1993-12-02 Merck Frosst Canada Inc Tetrahydrocarbazole Ester.
EP0480716A1 (en) 1990-10-12 1992-04-15 Merck Frosst Canada Inc. Saturated hydroxyalkylquinoline acids as leukotriene antagonists
US5410054A (en) * 1993-07-20 1995-04-25 Merck Frosst Canada, Inc. Heteroaryl quinolines as inhibitors of leukotriene biosynthesis
EP0885610A4 (en) * 1996-01-19 1999-04-21 Nippon Suisan Kaisha Ltd RELAXING SMOOTH MUSCLES OF THE TRACHEA
PL352840A1 (en) 1999-06-03 2003-09-08 Nippon Suisan Kaisha, Ltd. Tricyclic fused heterocycle compounds, process for preparing the same and use thereof
TWI275495B (en) * 2004-09-21 2007-03-11 Sony Corp Printer and printing method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4101667A (en) * 1975-05-30 1978-07-18 Nippon Chemiphar Co., Ltd. Benzo[b,f]thiepin derivatives
JPS5346989A (en) * 1976-10-06 1978-04-27 Nippon Chemiphar Co Ltd Novel dibenzo(b,f)thiepin derivatives and their preparation
JPS6021156B2 (ja) * 1976-12-03 1985-05-25 日本ケミフア株式会社 ベンゾチエピン誘導体およびその製法

Also Published As

Publication number Publication date
PL117756B1 (en) 1981-08-31
DD140746A5 (de) 1980-03-26
ES479215A1 (es) 1979-07-01
AU517813B2 (en) 1981-08-27
AR222666A1 (es) 1981-06-15
ES471871A1 (es) 1979-10-01
IE781488L (en) 1979-01-26
GR67276B (da) 1981-06-26
AU3817778A (en) 1980-01-24
PL120813B1 (en) 1982-03-31
ES479216A1 (es) 1979-07-01
ES479217A1 (es) 1979-07-01
EP0011067A1 (en) 1980-05-28
PL208653A1 (pl) 1979-06-04
IT7850375A0 (it) 1978-07-19
EP0011067B1 (en) 1982-04-21
IE47553B1 (en) 1984-04-18
JPS5444691A (en) 1979-04-09
JPS6250470B2 (da) 1987-10-24
AR226527A1 (es) 1982-07-30
CA1128048A (en) 1982-07-20
IT1107485B (it) 1985-11-25
NO782539L (no) 1979-01-29
ES479218A1 (es) 1979-11-01
PT68303A (en) 1978-08-01
FI782323A (fi) 1979-01-27
DE2861754D1 (en) 1982-06-03
PL116355B1 (en) 1981-06-30

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Legal Events

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