DK3250202T3 - Sammensætning til anvendelse til forøgelse af effektiviteten af inkorporering af hæmatopoetiske stamceller efter transplantation - Google Patents

Sammensætning til anvendelse til forøgelse af effektiviteten af inkorporering af hæmatopoetiske stamceller efter transplantation Download PDF

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Publication number
DK3250202T3
DK3250202T3 DK16701770.6T DK16701770T DK3250202T3 DK 3250202 T3 DK3250202 T3 DK 3250202T3 DK 16701770 T DK16701770 T DK 16701770T DK 3250202 T3 DK3250202 T3 DK 3250202T3
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transplantation
incorporation
increasing
efficiency
composition
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DK16701770.6T
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Michael Freissmuth
Eva-Maria Zebedin-Brandl
Zahra Kazemi
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Scipharm S A R L
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
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    • A61K31/5578Eicosanoids, e.g. leukotrienes or prostaglandins having a pentalene ring system, e.g. carbacyclin, iloprost
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
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    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0669Bone marrow stromal cells; Whole bone marrow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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  • Immunology (AREA)
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  • Developmental Biology & Embryology (AREA)
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  • Wood Science & Technology (AREA)
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK16701770.6T 2015-01-27 2016-01-27 Sammensætning til anvendelse til forøgelse af effektiviteten af inkorporering af hæmatopoetiske stamceller efter transplantation DK3250202T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15152664 2015-01-27
PCT/EP2016/051672 WO2016120310A1 (en) 2015-01-27 2016-01-27 Composition for use in increasing engraftment efficacy of haematopoetic stem cells after transplantation

Publications (1)

Publication Number Publication Date
DK3250202T3 true DK3250202T3 (da) 2021-05-31

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DK16701770.6T DK3250202T3 (da) 2015-01-27 2016-01-27 Sammensætning til anvendelse til forøgelse af effektiviteten af inkorporering af hæmatopoetiske stamceller efter transplantation

Country Status (24)

Country Link
US (1) US10226465B2 (da)
EP (1) EP3250202B1 (da)
JP (1) JP6669762B2 (da)
KR (1) KR102577669B1 (da)
CN (1) CN107548305A (da)
AU (1) AU2016212090B2 (da)
BR (1) BR112017016077A2 (da)
CA (1) CA2973146C (da)
CL (1) CL2017001903A1 (da)
CY (1) CY1124317T1 (da)
DK (1) DK3250202T3 (da)
EA (1) EA039149B1 (da)
ES (1) ES2872698T3 (da)
HR (1) HRP20210930T1 (da)
HU (1) HUE054615T2 (da)
IL (1) IL253389B (da)
LT (1) LT3250202T (da)
PL (1) PL3250202T3 (da)
PT (1) PT3250202T (da)
RS (1) RS61945B1 (da)
SG (1) SG11201705812SA (da)
SI (1) SI3250202T1 (da)
UA (1) UA122488C2 (da)
WO (1) WO2016120310A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2970913B1 (en) 2013-03-15 2018-08-22 LongBoat Explorers AB Cells, methods and apparatuses for umbilical cord blood collection and isolation of cells
US11542473B2 (en) 2016-10-21 2023-01-03 Amniotics Ab Methods and compositions for generating hematopoietic cells
US11213546B2 (en) 2017-09-07 2022-01-04 Emory University Methods to mobilize tissue resident cells for adoptive t cell therapy
WO2020047236A1 (en) * 2018-08-30 2020-03-05 The Regents Of The University Of California Mobilization and collection of peripheral blood hematopoietic stem cells from deceased donors
EP3647413A1 (en) * 2018-10-31 2020-05-06 Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas O.A., M.P. (CIEMAT) Improvements for performing and facilitating the recovery after hematopoietic stem cell transplantation
WO2021076042A2 (en) 2019-10-18 2021-04-22 Amniotics Ab Processes and apparatuses for obtaining amniotic mesenchymal stem cells from amniotic fluid and cells derived thereof
EP4196260A1 (en) * 2020-08-14 2023-06-21 Navan Technologies, Inc. Methods and apparatuses for biomolecule delivery to primary human hematopoietic stem cells using nanostraws
CN112961827B (zh) * 2021-04-25 2024-04-26 河南省肿瘤医院 佛司可林在t细胞培养中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040247574A1 (en) * 2003-05-27 2004-12-09 Christopherson Kent W. Methods for enhancing stem cell engraftment during transplantation
US20080221200A1 (en) * 2005-09-30 2008-09-11 Malcolm Allison Combination of Organic Compounds
JP2010518004A (ja) * 2007-02-01 2010-05-27 ネフロジェン, エルエルシー 幹細胞ホーミングの増強および臓器機能障害または臓器不全の治療
WO2009152186A1 (en) * 2008-06-09 2009-12-17 American Stem Cell, Inc. Methods for enhancing cell therapy efficacy including treatment with cd26 peptidase inhibitors
WO2012074676A2 (en) 2010-11-09 2012-06-07 Emory University Glp-1 agonists, dpp-4 inhibitors, compositions, and uses related thereto
SG191908A1 (en) * 2011-01-13 2013-08-30 Scipharm Sarl Method for enhancing engraftment of haematopoetic stem cells
US20140288010A1 (en) * 2013-02-22 2014-09-25 Georgia Regents Research Institute, Inc. Compositions and Methods for Increasing Stem Cell Survival

Also Published As

Publication number Publication date
RS61945B1 (sr) 2021-07-30
US20180008606A1 (en) 2018-01-11
JP2018505171A (ja) 2018-02-22
CA2973146C (en) 2024-01-09
SG11201705812SA (en) 2017-08-30
ES2872698T3 (es) 2021-11-02
IL253389B (en) 2021-02-28
IL253389A0 (en) 2017-09-28
LT3250202T (lt) 2021-06-25
PL3250202T3 (pl) 2021-08-30
HUE054615T2 (hu) 2021-09-28
EA201791703A1 (ru) 2017-11-30
AU2016212090B2 (en) 2021-05-20
CA2973146A1 (en) 2016-08-04
UA122488C2 (uk) 2020-11-25
WO2016120310A1 (en) 2016-08-04
SI3250202T1 (sl) 2021-07-30
CN107548305A (zh) 2018-01-05
CL2017001903A1 (es) 2018-03-23
EP3250202A1 (en) 2017-12-06
KR20170106980A (ko) 2017-09-22
EA039149B1 (ru) 2021-12-10
US10226465B2 (en) 2019-03-12
PT3250202T (pt) 2021-06-17
EP3250202B1 (en) 2021-03-10
AU2016212090A1 (en) 2017-08-03
CY1124317T1 (el) 2022-07-22
BR112017016077A2 (pt) 2018-04-03
HRP20210930T1 (hr) 2021-09-03
JP6669762B2 (ja) 2020-03-18
KR102577669B1 (ko) 2023-09-12

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