DK3234160T3 - Sammensætninger og fremgangsmåder til hjælper-stamme-medieret svampegenommodifikation - Google Patents
Sammensætninger og fremgangsmåder til hjælper-stamme-medieret svampegenommodifikation Download PDFInfo
- Publication number
- DK3234160T3 DK3234160T3 DK15823266T DK15823266T DK3234160T3 DK 3234160 T3 DK3234160 T3 DK 3234160T3 DK 15823266 T DK15823266 T DK 15823266T DK 15823266 T DK15823266 T DK 15823266T DK 3234160 T3 DK3234160 T3 DK 3234160T3
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- DK
- Denmark
- Prior art keywords
- trible
- procedures
- help
- compositions
- gene modification
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
- C12N15/04—Fungi
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Mycology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462092444P | 2014-12-16 | 2014-12-16 | |
| PCT/US2015/066178 WO2016100562A1 (en) | 2014-12-16 | 2015-12-16 | Compositions and methods for helper strain-mediated fungal genome modification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3234160T3 true DK3234160T3 (da) | 2019-12-02 |
Family
ID=55083508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15823266T DK3234160T3 (da) | 2014-12-16 | 2015-12-16 | Sammensætninger og fremgangsmåder til hjælper-stamme-medieret svampegenommodifikation |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10655148B2 (da) |
| EP (1) | EP3234160B1 (da) |
| JP (1) | JP6725513B2 (da) |
| CN (1) | CN107223157B (da) |
| DK (1) | DK3234160T3 (da) |
| WO (1) | WO2016100562A1 (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3329001B1 (en) * | 2015-07-28 | 2021-09-22 | Danisco US Inc. | Genome editing systems and methods of use |
| WO2018009822A1 (en) * | 2016-07-08 | 2018-01-11 | Ohio State Innovation Foundation | Modified nucleic acids, hybrid guide rnas, and uses thereof |
| CN110114461A (zh) | 2016-08-17 | 2019-08-09 | 博德研究所 | 新型crispr酶和*** |
| US11591601B2 (en) | 2017-05-05 | 2023-02-28 | The Broad Institute, Inc. | Methods for identification and modification of lncRNA associated with target genotypes and phenotypes |
| CN108085317B (zh) * | 2018-01-17 | 2019-06-21 | 四川大学 | 一种特异性靶向变异链球菌gtfB位点的CRISPR-B基因编辑方法及应用 |
| JP7376505B2 (ja) | 2018-04-24 | 2023-11-08 | ダニスコ・ユーエス・インク | 粘性が低下した表現型を含む糸状菌株 |
| KR20210038591A (ko) | 2018-07-30 | 2021-04-07 | 다니스코 유에스 인크. | 향상된 단백질 생산성 표현형을 포함하는 돌연변이체 및 유전자 변형된 사상성 진균 균주 및 이의 방법 |
| KR102126573B1 (ko) * | 2018-10-18 | 2020-06-26 | 대한민국 | CRISPR-Cas9 시스템을 이용한 유색고약버섯의 리그닌 분해효소의 유전자 편집방법 및 이의 용도 |
| WO2020236967A1 (en) | 2019-05-20 | 2020-11-26 | The Broad Institute, Inc. | Random crispr-cas deletion mutant |
| WO2021041922A1 (en) | 2019-08-30 | 2021-03-04 | The Broad Institute, Inc. | Crispr-associated mu transposase systems |
| CN110628806B (zh) * | 2019-09-23 | 2021-09-21 | 华南理工大学 | 一种高产β-紫罗兰酮基因工程菌及其构建方法和应用 |
| EP4051793A1 (en) | 2019-10-28 | 2022-09-07 | Danisco US Inc | Microbial host cells for the production of heterologous cyanuric acid hydrolases and biuret hydrolases |
| JP2022553854A (ja) | 2019-11-08 | 2022-12-26 | ダニスコ・ユーエス・インク | タンパク質生産性が増強された表現型を含む糸状菌株及びその方法 |
| WO2024102556A1 (en) | 2022-11-11 | 2024-05-16 | Danisco Us Inc. | Filamentous fungal strains comprising enhanced protein productivity phenotypes and methods thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5107065A (en) | 1986-03-28 | 1992-04-21 | Calgene, Inc. | Anti-sense regulation of gene expression in plant cells |
| US5683899A (en) | 1994-02-03 | 1997-11-04 | University Of Hawaii | Methods and compositions for combinatorial-based discovery of new multimeric molecules |
| WO1998041621A1 (en) * | 1997-03-18 | 1998-09-24 | Millennium Pharmaceuticals, Inc. | Aspergillus fumigatus auxotrophs, auxotrophic markers and polynucleotides encoding same |
| WO2008138835A1 (en) * | 2007-05-09 | 2008-11-20 | Novozymes A/S | Expression cloning method suitable for selecting library clones producing a polypeptide of interest |
| WO2013141680A1 (en) | 2012-03-20 | 2013-09-26 | Vilnius University | RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
-
2015
- 2015-12-16 CN CN201580076158.XA patent/CN107223157B/zh active Active
- 2015-12-16 WO PCT/US2015/066178 patent/WO2016100562A1/en active Application Filing
- 2015-12-16 DK DK15823266T patent/DK3234160T3/da active
- 2015-12-16 US US15/536,892 patent/US10655148B2/en active Active
- 2015-12-16 EP EP15823266.0A patent/EP3234160B1/en active Active
- 2015-12-16 JP JP2017532760A patent/JP6725513B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10655148B2 (en) | 2020-05-19 |
| CN107223157A (zh) | 2017-09-29 |
| EP3234160A1 (en) | 2017-10-25 |
| CN107223157B (zh) | 2021-01-08 |
| JP6725513B2 (ja) | 2020-07-22 |
| WO2016100562A1 (en) | 2016-06-23 |
| US20170362610A1 (en) | 2017-12-21 |
| EP3234160B1 (en) | 2019-08-28 |
| JP2017538424A (ja) | 2017-12-28 |
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