DK3187589T3 - Baculovirus-baseret produktion af biofarmaceutiske midler fri for forurenende baculovirale virioner - Google Patents
Baculovirus-baseret produktion af biofarmaceutiske midler fri for forurenende baculovirale virioner Download PDFInfo
- Publication number
- DK3187589T3 DK3187589T3 DK16205440.7T DK16205440T DK3187589T3 DK 3187589 T3 DK3187589 T3 DK 3187589T3 DK 16205440 T DK16205440 T DK 16205440T DK 3187589 T3 DK3187589 T3 DK 3187589T3
- Authority
- DK
- Denmark
- Prior art keywords
- based production
- baculovirus based
- biopharmaceuticals
- free
- baculoviral virions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14151—Methods of production or purification of viral material
- C12N2710/14152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/50—Vectors for producing vectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09305761A EP2292781A1 (en) | 2009-08-17 | 2009-08-17 | Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions |
| EP15168775.3A EP2933336B1 (en) | 2009-08-17 | 2010-08-05 | Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3187589T3 true DK3187589T3 (da) | 2020-04-14 |
Family
ID=41203903
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10743083.7T DK2467489T3 (da) | 2009-08-17 | 2010-08-05 | Baculovirus-baseret produktion af biofarmaceutiske midler frie for forurenende baculovirale virioner |
| DK16205440.7T DK3187589T3 (da) | 2009-08-17 | 2010-08-05 | Baculovirus-baseret produktion af biofarmaceutiske midler fri for forurenende baculovirale virioner |
| DK15168775.3T DK2933336T3 (da) | 2009-08-17 | 2010-08-05 | Baculovirus-baseret produktion af biofarmaceutika frie for forurenende baculovirale virioner |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10743083.7T DK2467489T3 (da) | 2009-08-17 | 2010-08-05 | Baculovirus-baseret produktion af biofarmaceutiske midler frie for forurenende baculovirale virioner |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15168775.3T DK2933336T3 (da) | 2009-08-17 | 2010-08-05 | Baculovirus-baseret produktion af biofarmaceutika frie for forurenende baculovirale virioner |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US8993317B2 (da) |
| EP (4) | EP2292781A1 (da) |
| CN (1) | CN102686732A (da) |
| CA (2) | CA3050271A1 (da) |
| DK (3) | DK2467489T3 (da) |
| ES (3) | ES2627744T3 (da) |
| HU (1) | HUE025056T2 (da) |
| PL (2) | PL3187589T3 (da) |
| PT (3) | PT3187589T (da) |
| WO (1) | WO2011020710A2 (da) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2292781A1 (en) * | 2009-08-17 | 2011-03-09 | Genethon | Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions |
| WO2013014256A1 (en) * | 2011-07-27 | 2013-01-31 | Gbiotech Sarl | Production of recombinant protein in insect cells using a baculovirus expression system |
| FR2978456B1 (fr) * | 2011-07-27 | 2015-02-20 | Genethon | Systeme baculoviral pour l'expression d'un vecteur de therapie genique |
| TWI702955B (zh) | 2012-05-15 | 2020-09-01 | 澳大利亞商艾佛蘭屈澳洲私營有限公司 | 使用腺相關病毒（ａａｖ）ｓｆｌｔ-１治療老年性黃斑部退化（ａｍｄ） |
| RU2619161C2 (ru) * | 2012-06-12 | 2017-05-12 | Альтернативе Гене Экспрессион С.Л. | Элементы рекомбинантной днк для экспрессии рекомбинантных белков в клетке-хозяине |
| AU2015231439B2 (en) | 2014-03-17 | 2019-11-14 | Adverum Biotechnologies, Inc. | Compositions and methods for enhanced gene expression in cone cells |
| US10577627B2 (en) | 2014-06-09 | 2020-03-03 | Voyager Therapeutics, Inc. | Chimeric capsids |
| MX2017005834A (es) | 2014-11-05 | 2017-11-17 | Voyager Therapeutics Inc | Polinucleotidos aad para el tratamiento de la enfermedad de parkinson. |
| KR102599909B1 (ko) | 2014-11-14 | 2023-11-09 | 보이저 테라퓨틱스, 인크. | 근위축성 측삭 경화증(als)을 치료하는 조성물 및 방법 |
| RU2749882C2 (ru) | 2014-11-14 | 2021-06-18 | Вояджер Терапьютикс, Инк. | Модулирующие полинуклеотиды |
| EP3230441A4 (en) | 2014-12-12 | 2018-10-03 | Voyager Therapeutics, Inc. | Compositions and methods for the production of scaav |
| KR20170137730A (ko) | 2015-03-02 | 2017-12-13 | 애드베룸 바이오테크놀로지스, 인코포레이티드 | 망막 추상체에 폴리뉴클레오타이드의 유리체 내 전달을 위한 조성물 및 방법 |
| ES2865487T3 (es) | 2015-09-28 | 2021-10-15 | Univ North Carolina Chapel Hill | Métodos y composiciones para vectores virales que evaden los anticuerpos |
| GB2545763A (en) | 2015-12-23 | 2017-06-28 | Adverum Biotechnologies Inc | Mutant viral capsid libraries and related systems and methods |
| WO2017189959A1 (en) | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| WO2017189964A2 (en) | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| SG11201809643UA (en) | 2016-05-18 | 2018-12-28 | Voyager Therapeutics Inc | Compositions and methods of treating huntington's disease |
| IL302748A (en) | 2016-05-18 | 2023-07-01 | Voyager Therapeutics Inc | modulatory polynucleotides |
| AU2017277304B2 (en) * | 2016-06-07 | 2023-07-20 | Cepheid | Thermostable polymerase inhibitor compositions and methods |
| AU2017321488B2 (en) | 2016-08-30 | 2022-10-20 | The Regents Of The University Of California | Methods for biomedical targeting and delivery and devices and systems for practicing the same |
| MX2019013172A (es) | 2017-05-05 | 2020-09-07 | Voyager Therapeutics Inc | Composiciones y metodos para tratar la enfermedad de huntington. |
| WO2018204786A1 (en) | 2017-05-05 | 2018-11-08 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| CN111132626B (zh) | 2017-07-17 | 2024-01-30 | 沃雅戈治疗公司 | 轨迹阵列引导*** |
| EP3662060A2 (en) | 2017-08-03 | 2020-06-10 | Voyager Therapeutics, Inc. | Compositions and methods for delivery of aav |
| EP3697908A1 (en) | 2017-10-16 | 2020-08-26 | Voyager Therapeutics, Inc. | Treatment of amyotrophic lateral sclerosis (als) |
| TWI804518B (zh) | 2017-10-16 | 2023-06-11 | 美商航海家醫療公司 | 肌萎縮性脊髓側索硬化症(als)之治療 |
| CN112272672A (zh) | 2018-04-03 | 2021-01-26 | 斯特里迪比奥公司 | 抗体逃避性病毒载体 |
| WO2019237374A1 (zh) * | 2018-06-16 | 2019-12-19 | 深圳市博奥康生物科技有限公司 | Mtabc3基因定点整合至a375细胞的方法及其应用 |
| WO2019237376A1 (zh) * | 2018-06-16 | 2019-12-19 | 深圳市博奥康生物科技有限公司 | TXGP1基因定点整合至Raji细胞的方法及其应用 |
| WO2019237377A1 (zh) * | 2018-06-16 | 2019-12-19 | 深圳市博奥康生物科技有限公司 | 一种将SLEB2基因定点整合至Jurkat细胞的方法及其应用 |
| CN108823176B (zh) * | 2018-07-20 | 2021-09-28 | 山西大学 | 一种重组杆状病毒及其构建方法和应用 |
| CN108998455B (zh) * | 2018-08-13 | 2021-03-16 | 西南大学 | 家蚕核型多角体病毒诱导型39k启动子及其重组载体和应用 |
| CN111434774B (zh) * | 2019-01-11 | 2023-06-23 | 陕西杆粒生物科技有限公司 | 一种解除高滴度抑制的杆状病毒表达载体 |
| AR118465A1 (es) | 2019-03-21 | 2021-10-06 | Stridebio Inc | Vectores de virus adenoasociados recombinantes |
| WO2020264139A1 (en) * | 2019-06-26 | 2020-12-30 | Virovek, Inc. | Baculovirus expression system |
| IL292297A (en) | 2019-10-17 | 2022-06-01 | Stridebio Inc | Adeno-associated viral vectors for the treatment of Niemann-Pick type c disease |
| CN110940807A (zh) * | 2019-11-08 | 2020-03-31 | 江苏科技大学 | 研究家蚕基因抑制BmNPV DNA复制相关基因的表达的方法 |
| EP4199971A1 (en) * | 2020-08-23 | 2023-06-28 | Bioverativ Therapeutics Inc. | Modified baculovirus system for improved production of closed-ended dna (cedna) |
| WO2023028440A2 (en) * | 2021-08-23 | 2023-03-02 | Bioverativ Therapeutics Inc. | Baculovirus expression system |
| CN114058598B (zh) * | 2021-11-04 | 2023-04-28 | 中国科学院精密测量科学与技术创新研究院 | 新的重组杆状病毒基因组***位点及其应用 |
| TW202404993A (zh) | 2022-04-11 | 2024-02-01 | 美商特納亞治療股份有限公司 | 具經工程化蛋白殼之腺相關病毒 |
| CN118086400B (zh) * | 2024-04-17 | 2024-07-19 | 和元生物技术（上海）股份有限公司 | 核酸分子、包含其的重组杆状病毒及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4745051A (en) | 1983-05-27 | 1988-05-17 | The Texas A&M University System | Method for producing a recombinant baculovirus expression vector |
| EP0127839B1 (en) | 1983-05-27 | 1992-07-15 | THE TEXAS A&M UNIVERSITY SYSTEM | Method for producing a recombinant baculovirus expression vector |
| DK518384A (da) | 1984-01-31 | 1985-07-01 | Idaho Res Found | Vektor til fremstilling af et gen-produkt i insektceller, fremgangsmaade til dens fremstilling samt dens anvendelse |
| CN1062601C (zh) * | 1992-03-24 | 2001-02-28 | 剑桥药物研究有限公司 | 病毒疫苗 |
| FR2756297B1 (fr) * | 1996-11-22 | 1999-01-08 | Centre Nat Rech Scient | Procede de production de virus recombinants |
| GB9919409D0 (en) * | 1999-08-18 | 1999-10-20 | Univ Oxford Brookes | Baculovirus expression system |
| EP1543128A4 (en) * | 2002-07-18 | 2008-02-20 | Invitrogen Corp | VIRUS VECTORS WITH RECOMBINATION SITES |
| WO2005072364A2 (en) * | 2004-01-27 | 2005-08-11 | University Of Florida | A modified baculovirus expression system for production of pseudotyped raav vector |
| EP2292781A1 (en) | 2009-08-17 | 2011-03-09 | Genethon | Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions |
-
2009
- 2009-08-17 EP EP09305761A patent/EP2292781A1/en not_active Withdrawn
-
2010
- 2010-08-05 EP EP15168775.3A patent/EP2933336B1/en not_active Not-in-force
- 2010-08-05 EP EP16205440.7A patent/EP3187589B1/en active Active
- 2010-08-05 PT PT162054407T patent/PT3187589T/pt unknown
- 2010-08-05 WO PCT/EP2010/061456 patent/WO2011020710A2/en active Application Filing
- 2010-08-05 ES ES15168775.3T patent/ES2627744T3/es active Active
- 2010-08-05 PT PT107430837T patent/PT2467489E/pt unknown
- 2010-08-05 DK DK10743083.7T patent/DK2467489T3/da active
- 2010-08-05 DK DK16205440.7T patent/DK3187589T3/da active
- 2010-08-05 ES ES16205440T patent/ES2787706T3/es active Active
- 2010-08-05 DK DK15168775.3T patent/DK2933336T3/da active
- 2010-08-05 CA CA3050271A patent/CA3050271A1/en not_active Abandoned
- 2010-08-05 US US13/390,806 patent/US8993317B2/en not_active Expired - Fee Related
- 2010-08-05 EP EP10743083.7A patent/EP2467489B1/en active Active
- 2010-08-05 PT PT151687753T patent/PT2933336T/pt unknown
- 2010-08-05 ES ES10743083.7T patent/ES2542740T3/es active Active
- 2010-08-05 HU HUE10743083A patent/HUE025056T2/en unknown
- 2010-08-05 PL PL16205440T patent/PL3187589T3/pl unknown
- 2010-08-05 PL PL10743083T patent/PL2467489T3/pl unknown
- 2010-08-05 CN CN2010800456298A patent/CN102686732A/zh active Pending
- 2010-08-05 CA CA2771250A patent/CA2771250C/en not_active Expired - Fee Related
-
2015
- 2015-03-27 US US14/670,459 patent/US9862934B2/en active Active
-
2017
- 2017-12-14 US US15/841,359 patent/US10428315B2/en not_active Expired - Fee Related
-
2019
- 2019-08-27 US US16/551,787 patent/US11236307B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3187589T3 (da) | Baculovirus-baseret produktion af biofarmaceutiske midler fri for forurenende baculovirale virioner | |
| DK2449057T3 (da) | Fremgangsmåde til omdannelse af lignocellulosematerialer til anvendelige kemikalier | |
| DK2422547T3 (da) | Indikator af PS- til CS-handover | |
| DK3550016T3 (da) | Sammensætninger til saccharificering af cellulosemateriale | |
| DK2435398T3 (da) | Fremgangsmåde til produktion af benzofuraner | |
| DK2401497T3 (da) | Fremgangsmåde til fremstilling af vindmølleblade | |
| DK2496562T3 (da) | Fremgangsmåde til fremstilling af calcobutrol | |
| DK2662352T3 (da) | Fremgangsmåde til fremstilling af phenylacetamidforbindelse | |
| DK2461685T3 (da) | Blandinger af mesoioniske pesticider | |
| DK2526425T3 (da) | Fremgangsmåde til diagnosticering af endometriel receptivitet | |
| BRPI1006847A2 (pt) | desenvolvimento de um construtor de hidroxicarboxilato de alumínio. | |
| DK2521750T3 (da) | Hærdning af væsker | |
| DK2498771T3 (da) | Anvendelse af bethanechol til behandling af xerostomi | |
| ES2451507T8 (es) | Brida de fijación | |
| BRPI1010594A2 (pt) | conjunto de mastro turbina de vento | |
| DK2411490T3 (da) | Fremgangsmåde til fremstilling af bioolie | |
| DK2593449T3 (da) | Fremgangsmåde til syntese af benzothiadiazolforbindelse | |
| DK2404059T3 (da) | Fremgangsmåde til overvågning af vindturbiner | |
| DK3278809T3 (da) | Sikker indgivelse af desmopressin | |
| DK2430196T3 (da) | Fremgangsmåde til fremstilling af alkoholer | |
| DK2459129T3 (da) | Forbedringer af karstøtteanordninger | |
| BR112012000890A2 (pt) | formas de base livre cristalina de um composto bifenil | |
| DK2598880T3 (da) | Fremgangsmåde til detektering af forekomsten af en gynækologisk vækst | |
| EP2423203A4 (en) | CRYSTAL OF A BENZOXAZINONE COMPOUND | |
| DK2516359T3 (da) | Fremgangsmåde til fremstilling af ethylbenzen |