DK3181691T3 - Anti-fgf23-antistof og en farmaceutisk sammensætning omfattende samme - Google Patents

Anti-fgf23-antistof og en farmaceutisk sammensætning omfattende samme Download PDF

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Publication number
DK3181691T3
DK3181691T3 DK17152168.5T DK17152168T DK3181691T3 DK 3181691 T3 DK3181691 T3 DK 3181691T3 DK 17152168 T DK17152168 T DK 17152168T DK 3181691 T3 DK3181691 T3 DK 3181691T3
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DK
Denmark
Prior art keywords
same
pharmaceutical composition
composition including
fgf23 antibody
fgf23
Prior art date
Application number
DK17152168.5T
Other languages
English (en)
Inventor
Yuji Yamazaki
Itaru Urakawa
Hitoshi Yoshida
Yukiko Aono
Takeyoshi Yamashita
Takashi Shimada
Hisashi Hasegawa
Original Assignee
Kyowa Kirin Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39690189&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3181691(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kyowa Kirin Co Ltd filed Critical Kyowa Kirin Co Ltd
Application granted granted Critical
Publication of DK3181691T3 publication Critical patent/DK3181691T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Urology & Nephrology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
DK17152168.5T 2007-02-14 2008-02-14 Anti-fgf23-antistof og en farmaceutisk sammensætning omfattende samme DK3181691T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007034018 2007-02-14
EP12170984.4A EP2502996B1 (en) 2007-02-14 2008-02-14 Anti-FGF23 antibody and pharmaceutical composition comprising the same

Publications (1)

Publication Number Publication Date
DK3181691T3 true DK3181691T3 (da) 2020-08-17

Family

ID=39690189

Family Applications (3)

Application Number Title Priority Date Filing Date
DK12170984.4T DK2502996T3 (da) 2007-02-14 2008-02-14 Anti-FGF23-antistof og farmaceutisk sammensætning omfattende samme
DK17152168.5T DK3181691T3 (da) 2007-02-14 2008-02-14 Anti-fgf23-antistof og en farmaceutisk sammensætning omfattende samme
DK08711707.3T DK2128253T3 (da) 2007-02-14 2008-02-14 Anti-fgf23-antistof og farmaceutisk sammensætning omfattende samme

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK12170984.4T DK2502996T3 (da) 2007-02-14 2008-02-14 Anti-FGF23-antistof og farmaceutisk sammensætning omfattende samme

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK08711707.3T DK2128253T3 (da) 2007-02-14 2008-02-14 Anti-fgf23-antistof og farmaceutisk sammensætning omfattende samme

Country Status (23)

Country Link
US (4) US7883705B2 (da)
EP (3) EP2128253B1 (da)
JP (1) JP4800396B2 (da)
KR (1) KR101462291B1 (da)
CN (2) CN102702355B (da)
AU (1) AU2008215346B2 (da)
CA (1) CA2677782C (da)
CY (3) CY1118835T1 (da)
DK (3) DK2502996T3 (da)
ES (3) ES2811318T3 (da)
FR (1) FR18C1032I2 (da)
HK (2) HK1140228A1 (da)
HR (2) HRP20170548T1 (da)
HU (3) HUE050517T2 (da)
LT (3) LT3181691T (da)
LU (2) LUC00081I2 (da)
NL (1) NL300945I2 (da)
NO (1) NO2018025I1 (da)
PL (3) PL2128253T3 (da)
PT (3) PT2502996T (da)
SI (2) SI2502996T1 (da)
TW (1) TWI422593B (da)
WO (1) WO2008099969A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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ES2344679T3 (es) * 2000-08-11 2010-09-03 Kyowa Hakko Kirin Co., Ltd. Polipeptidos que controlan el metabolismo del acido fosforico, el metabolismo del calcio, el metabolismo de la calcificacion y de la vitamina d y moleculas de adn que los codifican.
KR101016476B1 (ko) * 2001-12-28 2011-02-24 교와 핫꼬 기린 가부시키가이샤 섬유아세포 증식 인자-23에 대한 항체
US7883705B2 (en) * 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same
WO2012050673A1 (en) * 2010-10-14 2012-04-19 Wisconsin Alumni Research Foundation Methods for the treatment of x-linked hypophosphatemia and related disorders
US20140294820A1 (en) 2011-06-24 2014-10-02 University Of Miami Fibroblast growth factor receptor inhibition for the treatment of disease
BR112016028567A2 (pt) * 2014-06-09 2018-01-30 Kyowa Hakko Kirin Co Ltd método para utilizar ligante anti-fgf23 e para tratar doença e/ou condição relacionada com fgf23 e para aumentar a remodelação óssea
WO2018069232A1 (en) 2016-10-10 2018-04-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the risk of having cardiac hypertrophy
JP7023932B2 (ja) 2017-03-30 2022-02-22 シスメックス株式会社 抗ApoA1抗体
AU2020253833A1 (en) * 2019-03-29 2021-10-28 Atarga, Llc Anti FGF23 antibody
TW202413406A (zh) * 2022-08-10 2024-04-01 日商協和麒麟股份有限公司 抗fgf23抗體或該抗體片段

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Also Published As

Publication number Publication date
KR20090114452A (ko) 2009-11-03
ES2811318T3 (es) 2021-03-11
TWI422593B (zh) 2014-01-11
US7883705B2 (en) 2011-02-08
CN102702355A (zh) 2012-10-03
PL2128253T3 (pl) 2015-04-30
EP3181691B1 (en) 2020-07-15
NO2018025I1 (no) 2018-08-09
KR101462291B1 (ko) 2014-11-14
ES2625823T3 (es) 2017-07-20
TW200902549A (en) 2009-01-16
AU2008215346A1 (en) 2008-08-21
CA2677782A1 (en) 2008-08-21
PT2502996T (pt) 2017-05-10
EP2128253A4 (en) 2010-03-10
NL300945I2 (en) 2020-05-13
FR18C1032I2 (fr) 2019-08-09
HK1140228A1 (en) 2010-10-08
WO2008099969A1 (ja) 2008-08-21
CN101652476A (zh) 2010-02-17
HUS1800034I1 (hu) 2018-09-28
PL3181691T3 (pl) 2020-11-02
FR18C1032I1 (da) 2018-08-31
CN102702355B (zh) 2014-09-24
US20190106485A1 (en) 2019-04-11
PL2502996T3 (pl) 2017-07-31
CY2018021I1 (el) 2019-07-10
AU2008215346B2 (en) 2013-01-10
PT2128253E (pt) 2015-02-04
EP2502996A2 (en) 2012-09-26
ES2530670T3 (es) 2015-03-04
CA2677782C (en) 2016-07-26
CY1118835T1 (el) 2018-01-10
LT2502996T (lt) 2017-06-26
DK2128253T3 (da) 2015-01-05
LUC00081I2 (da) 2018-10-01
LTPA2018508I1 (lt) 2018-09-10
HK1172917A1 (en) 2013-05-03
US9290569B2 (en) 2016-03-22
CY1123240T1 (el) 2021-10-29
JPWO2008099969A1 (ja) 2010-05-27
NL300945I1 (en) 2018-08-15
HRP20201266T1 (hr) 2021-02-05
US20090148461A1 (en) 2009-06-11
EP2128253A1 (en) 2009-12-02
EP3181691A1 (en) 2017-06-21
HRP20170548T1 (hr) 2017-08-25
EP2502996B1 (en) 2017-03-29
SI2502996T1 (sl) 2017-08-31
LTC2502996I2 (lt) 2019-05-10
LUC00082I2 (da) 2018-10-01
HUE031728T2 (en) 2017-07-28
US20110182913A1 (en) 2011-07-28
HUE050517T2 (hu) 2020-12-28
EP2502996A3 (en) 2013-04-10
US20160159895A1 (en) 2016-06-09
CY2018021I2 (el) 2019-07-10
LT3181691T (lt) 2020-08-25
CN101652476B (zh) 2012-07-04
SI3181691T1 (sl) 2020-09-30
EP2128253B1 (en) 2014-12-03
PT3181691T (pt) 2020-08-26
JP4800396B2 (ja) 2011-10-26
DK2502996T3 (da) 2017-05-08
US10202446B2 (en) 2019-02-12

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