DK3172317T3 - Fremgangsmåde til oprensning af poliovirus fra cellekulturer - Google Patents

Fremgangsmåde til oprensning af poliovirus fra cellekulturer Download PDF

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Publication number
DK3172317T3
DK3172317T3 DK15741534.0T DK15741534T DK3172317T3 DK 3172317 T3 DK3172317 T3 DK 3172317T3 DK 15741534 T DK15741534 T DK 15741534T DK 3172317 T3 DK3172317 T3 DK 3172317T3
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Denmark
Prior art keywords
poliovirus
cleaning
procedure
cell cultures
cultures
Prior art date
Application number
DK15741534.0T
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English (en)
Inventor
Mariken Segers
Nfor Beckley Kungah
Feras Nachmi Alazi
Vocht Marcel Leo De
Original Assignee
Janssen Vaccines & Prevention Bv
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Filing date
Publication date
Application filed by Janssen Vaccines & Prevention Bv filed Critical Janssen Vaccines & Prevention Bv
Application granted granted Critical
Publication of DK3172317T3 publication Critical patent/DK3172317T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32311Enterovirus
    • C12N2770/32351Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32611Poliovirus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32611Poliovirus
    • C12N2770/32651Methods of production or purification of viral material
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DK15741534.0T 2014-07-24 2015-07-21 Fremgangsmåde til oprensning af poliovirus fra cellekulturer DK3172317T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14178392 2014-07-24
EP14178399 2014-07-24
PCT/EP2015/066638 WO2016012445A2 (en) 2014-07-24 2015-07-21 Process for the purification of poliovirus from cell cultures

Publications (1)

Publication Number Publication Date
DK3172317T3 true DK3172317T3 (da) 2019-07-22

Family

ID=53719768

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15741534.0T DK3172317T3 (da) 2014-07-24 2015-07-21 Fremgangsmåde til oprensning af poliovirus fra cellekulturer

Country Status (14)

Country Link
US (1) US10294460B2 (da)
EP (1) EP3172317B1 (da)
JP (1) JP6385559B2 (da)
KR (1) KR102364111B1 (da)
CN (1) CN106574252B (da)
AU (1) AU2015294014B2 (da)
BR (1) BR112017001177B1 (da)
CA (1) CA2955877A1 (da)
DK (1) DK3172317T3 (da)
EA (1) EA034503B1 (da)
ES (1) ES2733489T3 (da)
PL (1) PL3172317T3 (da)
SG (1) SG11201700361QA (da)
WO (1) WO2016012445A2 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3172317B1 (en) 2014-07-24 2019-05-01 Janssen Vaccines & Prevention B.V. Process for the purification of poliovirus from cell cultures
WO2016201224A1 (en) 2015-06-10 2016-12-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Processes for production and purification of nucleic acid-containing compositions
MX2019002495A (es) * 2016-09-01 2020-02-17 Takeda Vaccines Inc Metodos para producir virus para la produccion de vacunas.
WO2019155492A1 (en) * 2018-02-07 2019-08-15 Bharat Biotech International Limited A process for enterovirus purification and inactivation and vaccine compositions obtained thereof
WO2022132988A1 (en) * 2020-12-17 2022-06-23 Merck Sharp & Dohme Corp. Enterovirus purification with cation exchange chromatography
JP2023141423A (ja) * 2022-03-24 2023-10-05 国立大学法人 東京大学 ウイルスの精製方法
CN116987676B (zh) * 2023-09-27 2023-12-19 深圳源兴基因技术有限公司 一种微载体痘病毒高效培养方法

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US4525349A (en) 1981-12-29 1985-06-25 Societe Anonyme Dite: Institut Merueux Process for the large-scale production of a vaccine against poliomyelitis and the resulting vaccine
ES2333425T5 (es) 1995-06-15 2012-08-28 Crucell Holland B.V. Sistemas de empaquetado para adenovirus recombinante humano destinados a terapia génica
GB0002661D0 (en) 2000-02-04 2000-03-29 Biomade B V Method of stabilizing a hydrophobin-containing solution and a method of coating a surface with a hydrophobin
BR0207527A (pt) 2001-03-16 2004-02-25 Oncolytics Biotech Inc Método para produzir vìrus de uma cultura de células, composição, e, método para produzir reovìrus infeccioso
ES2357366T3 (es) 2002-05-14 2011-04-25 MERCK SHARP & DOHME CORP. Procedimientos de purificación de adenovirus.
CN1777622A (zh) * 2003-02-24 2006-05-24 施里昂药品股份公司 脊髓灰质炎病毒受体功能的调节
DE602004024964D1 (de) * 2003-03-10 2010-02-25 Novozymes As Verfahren zur herstellung von alkohol
EP1613729A1 (en) * 2003-04-04 2006-01-11 Novozymes A/S Mash viscosity reduction
JP2004313019A (ja) 2003-04-11 2004-11-11 Mitsubishi Kagaku Iatron Inc 組織抽出液の製造方法
WO2004099396A1 (en) 2003-05-09 2004-11-18 Crucell Holland B.V. Cultures of e1-immortalized cells and processes for culturing the same to increase product yields therefrom
AU2005214090B2 (en) * 2004-02-23 2008-09-11 Crucell Holland B.V. Virus purification methods
ES2456015T3 (es) 2004-03-05 2014-04-21 Dsm Ip Assets B.V. Procedimiento para cultivar células mediante perfusión continua y flujo tangencial alternante
EP1793852A1 (en) 2004-08-27 2007-06-13 Panacea Biotec Ltd. Inactivated poliomyelitis vaccine derived from sabin strain of polio virus
US7901921B2 (en) * 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
CN101155915B (zh) * 2005-04-11 2013-12-04 克鲁塞尔荷兰公司 利用超滤进行病毒纯化
US7968318B2 (en) * 2006-06-06 2011-06-28 Genencor International, Inc. Process for conversion of granular starch to ethanol
PT2634250T (pt) 2006-07-14 2017-07-13 Patheon Holdings I B V Processo melhorado para a cultura de células
AU2010272685B2 (en) 2009-07-16 2015-02-26 Crucell Holland B.V. Production of polio virus at high titers for vaccine production
AU2010305765B2 (en) * 2009-10-15 2015-07-02 Crucell Holland B.V. Method for the purification of adenovirus particles
CN102575233B (zh) 2009-10-15 2014-07-16 克鲁塞尔荷兰公司 从高细胞密度培养物纯化腺病毒的方法
EP2461162A1 (en) * 2010-12-03 2012-06-06 Texcell, . Method for determining the titre of viruses by using infectious standards
RU2013153507A (ru) 2011-06-06 2015-07-20 Биокарти Нв Селективный лизис клеток с помощью ионных поверхностно-активных веществ
EP3172317B1 (en) 2014-07-24 2019-05-01 Janssen Vaccines & Prevention B.V. Process for the purification of poliovirus from cell cultures

Also Published As

Publication number Publication date
EP3172317A2 (en) 2017-05-31
SG11201700361QA (en) 2017-02-27
US20170166872A1 (en) 2017-06-15
CN106574252A (zh) 2017-04-19
BR112017001177B1 (pt) 2022-05-24
CA2955877A1 (en) 2016-01-28
US10294460B2 (en) 2019-05-21
KR20170031242A (ko) 2017-03-20
ES2733489T3 (es) 2019-11-29
WO2016012445A3 (en) 2016-03-31
PL3172317T3 (pl) 2019-10-31
KR102364111B1 (ko) 2022-02-17
AU2015294014B2 (en) 2018-08-23
CN106574252B (zh) 2021-06-01
JP6385559B2 (ja) 2018-09-05
BR112017001177A2 (pt) 2017-11-21
EA034503B1 (ru) 2020-02-14
AU2015294014A1 (en) 2017-01-12
JP2017524360A (ja) 2017-08-31
EP3172317B1 (en) 2019-05-01
WO2016012445A2 (en) 2016-01-28
EA201790250A1 (ru) 2017-05-31

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