DK3142659T3 - Hiv-1 proteasehæmmere og anvendelser deraf - Google Patents

Hiv-1 proteasehæmmere og anvendelser deraf Download PDF

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Publication number
DK3142659T3
DK3142659T3 DK15792991.0T DK15792991T DK3142659T3 DK 3142659 T3 DK3142659 T3 DK 3142659T3 DK 15792991 T DK15792991 T DK 15792991T DK 3142659 T3 DK3142659 T3 DK 3142659T3
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DK
Denmark
Prior art keywords
hiv
protease inhibitors
protease
inhibitors
Prior art date
Application number
DK15792991.0T
Other languages
English (en)
Inventor
Arun K Ghosh
Venkateswara Kalapala Rao
Hiroaki Mitsuya
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Application granted granted Critical
Publication of DK3142659T3 publication Critical patent/DK3142659T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK15792991.0T 2014-05-16 2015-05-15 Hiv-1 proteasehæmmere og anvendelser deraf DK3142659T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461994462P 2014-05-16 2014-05-16
PCT/US2015/031181 WO2015175994A1 (en) 2014-05-16 2015-05-15 Hiv-1 protease inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
DK3142659T3 true DK3142659T3 (da) 2021-05-31

Family

ID=54480812

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15792991.0T DK3142659T3 (da) 2014-05-16 2015-05-15 Hiv-1 proteasehæmmere og anvendelser deraf

Country Status (5)

Country Link
US (1) US9670225B2 (da)
EP (1) EP3142659B1 (da)
JP (1) JP6622290B2 (da)
DK (1) DK3142659T3 (da)
WO (1) WO2015175994A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9670225B2 (en) 2014-05-16 2017-06-06 Purdue Research Foundation HIV-1 protease inhibitors and uses thereof
WO2017031220A1 (en) * 2015-08-17 2017-02-23 Ghosh Arun K Hiv-1 protease inhibitors and uses thereof
JP7098643B2 (ja) * 2016-11-09 2022-07-11 パーデュー・リサーチ・ファウンデーション Ｈｉｖ／ａｉｄｓに対する強力な三環式ｐ２リガンド含有ｈｉｖプロテアーゼ阻害剤
JOP20180009A1 (ar) 2017-02-06 2019-01-30 Gilead Sciences Inc مركبات مثبط فيروس hiv
WO2019006335A1 (en) * 2017-06-30 2019-01-03 Ghosh Arun K INHIBITORS OF HIV-1 PROTEASE AND USES THEREOF
TWI766172B (zh) 2018-07-30 2022-06-01 美商基利科學股份有限公司 抗hiv化合物
EP3938371A4 (en) * 2019-01-15 2023-01-18 Purdue Research Foundation HIV-1 PROTEASE INHIBITORS AND THEIR USES
CA3171361A1 (en) * 2020-03-18 2021-09-23 Arun K. Ghosh Tricyclic p2-ligand containing potent hiv-protease inhibitors
US20230399338A1 (en) 2022-06-10 2023-12-14 Arun K. Ghosh METHOD OF SYNTHESIZING (3S,3AR,5R,7AS,8S)- HEXAHYDRO-4H-3,5-METHANOFURO[2,3-b]PYRAN-8-OL

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2049547A2 (en) * 2006-07-21 2009-04-22 Gilead Sciences, Inc. Aza-peptide protease inhibitors
US20080070910A1 (en) * 2006-07-24 2008-03-20 Desai Manoj C Therapeutic compounds and methods
EP2304043A4 (en) * 2008-07-09 2012-05-30 Purdue Research Foundation HIV PROTEASE INHIBITORS AND METHOD FOR THEIR USE
JP6006211B2 (ja) * 2010-09-02 2016-10-12 パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ ３員環の縮合エーテルカルバメートおよびその使用
US9670225B2 (en) 2014-05-16 2017-06-06 Purdue Research Foundation HIV-1 protease inhibitors and uses thereof

Also Published As

Publication number Publication date
EP3142659B1 (en) 2021-03-24
US9670225B2 (en) 2017-06-06
WO2015175994A1 (en) 2015-11-19
JP2017515914A (ja) 2017-06-15
EP3142659A1 (en) 2017-03-22
JP6622290B2 (ja) 2019-12-18
US20170088555A1 (en) 2017-03-30
EP3142659A4 (en) 2017-09-27

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