DK3134407T3 - Salte og polymorfer af en substitueret imidazopyridinyl-aminopyridinforbindelse - Google Patents

Salte og polymorfer af en substitueret imidazopyridinyl-aminopyridinforbindelse Download PDF

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Publication number
DK3134407T3
DK3134407T3 DK15783385.6T DK15783385T DK3134407T3 DK 3134407 T3 DK3134407 T3 DK 3134407T3 DK 15783385 T DK15783385 T DK 15783385T DK 3134407 T3 DK3134407 T3 DK 3134407T3
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DK
Denmark
Prior art keywords
aminopyride
polymorphs
salts
compound
substituted imidazopyridinyl
Prior art date
Application number
DK15783385.6T
Other languages
English (en)
Inventor
Craig Bates
David P Reed
Jianmin Mao
Original Assignee
Arqule Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by Arqule Inc filed Critical Arqule Inc
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Publication of DK3134407T3 publication Critical patent/DK3134407T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/04Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK15783385.6T 2014-04-22 2015-04-22 Salte og polymorfer af en substitueret imidazopyridinyl-aminopyridinforbindelse DK3134407T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461982692P 2014-04-22 2014-04-22
PCT/US2015/027045 WO2015164479A1 (en) 2014-04-22 2015-04-22 Salts and polymorphs of a substituted imidazopyridinyl-aminopyridine compound

Publications (1)

Publication Number Publication Date
DK3134407T3 true DK3134407T3 (da) 2019-09-23

Family

ID=54321420

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15783385.6T DK3134407T3 (da) 2014-04-22 2015-04-22 Salte og polymorfer af en substitueret imidazopyridinyl-aminopyridinforbindelse

Country Status (20)

Country Link
US (1) US9422283B2 (da)
EP (2) EP3134407B1 (da)
JP (2) JP6961348B2 (da)
KR (1) KR20160143842A (da)
CN (2) CN111499627A (da)
AU (2) AU2015249809B2 (da)
BR (1) BR112016024521A2 (da)
CA (1) CA2945778A1 (da)
DK (1) DK3134407T3 (da)
ES (1) ES2745156T3 (da)
HU (1) HUE046150T2 (da)
IL (1) IL248342A (da)
MX (2) MX2016013911A (da)
PL (1) PL3134407T3 (da)
PT (1) PT3134407T (da)
RU (1) RU2732125C2 (da)
SG (1) SG11201608722QA (da)
TW (1) TWI652266B (da)
WO (1) WO2015164479A1 (da)
ZA (1) ZA201607107B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220024617A (ko) * 2019-07-17 2022-03-03 서밋 (옥스포드) 리미티드 리디닐라졸 및 이의 결정 형태의 제조방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
KR100830859B1 (ko) * 2000-04-27 2008-05-21 아스텔라스세이야쿠 가부시키가이샤 이미다조피리딘 유도체 및 이를 함유하는 의약 조성물
US6403588B1 (en) * 2000-04-27 2002-06-11 Yamanouchi Pharmaceutical Co., Ltd. Imidazopyridine derivatives
GB0206860D0 (en) * 2002-03-22 2002-05-01 Glaxo Group Ltd Compounds
CN102127078A (zh) * 2005-07-14 2011-07-20 安斯泰来制药株式会社 Janus激酶3的杂环类抑制剂
AU2007231577B2 (en) * 2006-03-22 2012-07-19 Vertex Pharmaceuticals Incorporated c-MET protein kinase inhibitors for the treatment of proliferative disorders
US8136543B2 (en) * 2009-01-27 2012-03-20 Fisher Controls International, Llc Axial flow control valves having an internal actuator
IT1395963B1 (it) * 2009-06-04 2012-11-02 Rottapharm Spa Forme cristalline di 6-(1h-imidazol-1-il)-2-fenil chinazolina e dei suoi sali
US8501770B2 (en) * 2009-12-30 2013-08-06 Arqule, Inc. Substituted imidazopyridinyl-aminopyridine compounds
ES2579855T3 (es) 2011-06-24 2016-08-17 Arqule, Inc. Compuestos de imidazopiridinil-aminopiridina sustituidos
US8815854B2 (en) 2011-06-24 2014-08-26 Arqule, Inc. Substituted imidazopyridinyl compounds

Also Published As

Publication number Publication date
AU2015249809B2 (en) 2019-05-02
PT3134407T (pt) 2019-09-27
US9422283B2 (en) 2016-08-23
WO2015164479A1 (en) 2015-10-29
EP3653627A1 (en) 2020-05-20
CN106795153B (zh) 2020-03-20
ES2745156T3 (es) 2020-02-27
TW201625606A (zh) 2016-07-16
CN106795153A (zh) 2017-05-31
CN111499627A (zh) 2020-08-07
MX2016013911A (es) 2017-03-07
JP2017513890A (ja) 2017-06-01
IL248342A (en) 2017-07-31
HUE046150T2 (hu) 2020-02-28
RU2016145264A3 (da) 2019-01-24
AU2019206118B2 (en) 2020-07-23
EP3134407B1 (en) 2019-07-10
RU2016145264A (ru) 2018-05-23
EP3134407A1 (en) 2017-03-01
SG11201608722QA (en) 2016-11-29
BR112016024521A2 (pt) 2017-08-15
PL3134407T3 (pl) 2019-11-29
JP6961348B2 (ja) 2021-11-05
EP3134407A4 (en) 2017-09-13
TWI652266B (zh) 2019-03-01
KR20160143842A (ko) 2016-12-14
ZA201607107B (en) 2018-05-30
JP2020073523A (ja) 2020-05-14
CA2945778A1 (en) 2015-10-29
AU2019206118A1 (en) 2019-08-08
RU2732125C2 (ru) 2020-09-11
AU2015249809A1 (en) 2016-11-03
US20150299195A1 (en) 2015-10-22
MX2020009412A (es) 2020-10-05

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