DK3126391T3 - ANTISTOFFER MOD HPA-1a - Google Patents

ANTISTOFFER MOD HPA-1a Download PDF

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Publication number
DK3126391T3
DK3126391T3 DK15713749T DK15713749T DK3126391T3 DK 3126391 T3 DK3126391 T3 DK 3126391T3 DK 15713749 T DK15713749 T DK 15713749T DK 15713749 T DK15713749 T DK 15713749T DK 3126391 T3 DK3126391 T3 DK 3126391T3
Authority
DK
Denmark
Prior art keywords
antibodies against
against hpa
hpa
antibodies
Prior art date
Application number
DK15713749T
Other languages
English (en)
Inventor
Terje Michaelsen
Mariana Eksteen
Anne Husebekk
Øistein Ihle
Bjørn Ragnar Skogen
Tor Brynjar Stuge
Heidi Tiller
Original Assignee
Univ I Tromsoe Norges Arktiske Univ
Univ Hospital Of North Norway
Norrinova Tech Transfer As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1405775.6A external-priority patent/GB201405775D0/en
Priority claimed from GBGB1417614.3A external-priority patent/GB201417614D0/en
Application filed by Univ I Tromsoe Norges Arktiske Univ, Univ Hospital Of North Norway, Norrinova Tech Transfer As filed Critical Univ I Tromsoe Norges Arktiske Univ
Application granted granted Critical
Publication of DK3126391T3 publication Critical patent/DK3126391T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2848Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515Complete light chain, i.e. VL + CL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54F(ab')2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/38Pediatrics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK15713749T 2014-03-31 2015-03-31 ANTISTOFFER MOD HPA-1a DK3126391T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1405775.6A GB201405775D0 (en) 2014-03-31 2014-03-31 Antibodies
GBGB1417614.3A GB201417614D0 (en) 2014-10-06 2014-10-06 Antibodies
PCT/EP2015/057102 WO2015150417A1 (en) 2014-03-31 2015-03-31 ANTIBODIES AGAINST HPA-1a

Publications (1)

Publication Number Publication Date
DK3126391T3 true DK3126391T3 (da) 2019-11-25

Family

ID=52785093

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15713749T DK3126391T3 (da) 2014-03-31 2015-03-31 ANTISTOFFER MOD HPA-1a

Country Status (21)

Country Link
US (2) US10882919B2 (da)
EP (1) EP3126391B1 (da)
AU (1) AU2015239606C1 (da)
BR (1) BR112016022508A2 (da)
CA (1) CA2943857C (da)
CY (1) CY1122728T1 (da)
DK (1) DK3126391T3 (da)
ES (1) ES2757596T3 (da)
HR (1) HRP20192097T1 (da)
HU (1) HUE047455T2 (da)
IL (1) IL247988B2 (da)
LT (1) LT3126391T (da)
ME (1) ME03655B (da)
MX (1) MX2016012620A (da)
NZ (1) NZ724772A (da)
PL (1) PL3126391T3 (da)
PT (1) PT3126391T (da)
RS (1) RS59704B1 (da)
RU (1) RU2688627C2 (da)
SI (1) SI3126391T1 (da)
WO (1) WO2015150417A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022212930A1 (en) * 2021-04-02 2022-10-06 Rallybio Ipa, Llc Method of administering anti-hpa-1a gamma globulin
EP4363444A1 (en) * 2021-07-01 2024-05-08 Rallybio IPA, LLC Administration of anti-hpa-1a antibodies
IL309661A (en) * 2021-07-01 2024-02-01 Rallybio Ipa Llc A method for administering an anti-HPA-1A monoclonal antibody
AU2022381210A1 (en) * 2021-11-08 2024-05-02 Rallybio Ipa, Llc ASSAYS FOR QUANTIFICATION OF ANTI-HPA-1a ANTIBODIES

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990010457A1 (en) 1989-03-14 1990-09-20 New York University Method of treating hiv infections using immunotoxins
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
DK1136556T3 (da) 1991-11-25 2005-10-03 Enzon Inc Fremgangsmåde til fremstilling af multivalente antigen-bindende proteiner
GB9223390D0 (en) 1992-11-07 1992-12-23 Common Services Agency Anti-hpa1 testing
GB9505447D0 (en) 1995-03-17 1995-05-03 Common Services Agency Competitive binding assay
AU7809698A (en) * 1997-06-05 1998-12-21 Johns Hopkins University, The Identification of human heavy chain antibody fragment directed against human platelet alloantigen 1a(hpa-1a)
GB9809951D0 (en) 1998-05-08 1998-07-08 Univ Cambridge Tech Binding molecules
US20030027207A1 (en) 2000-02-29 2003-02-06 Filpula David Ray Anti-platelet binding proteins and polymer conjugates containing the same
JP3312204B2 (ja) 2000-10-17 2002-08-05 学校法人 慶應義塾 血小板減少症の診断用キット
GB0315754D0 (en) 2003-07-04 2003-08-13 Univ Aberdeen Pharmaceutical compositions
WO2005075496A1 (en) 2004-02-06 2005-08-18 Canadian Blood Services A method for the simultaneous determination of blood group and platelet antigen genotypes
CA2590164A1 (en) 2005-01-26 2006-08-03 Amgen Fremont Inc. Antibodies against interleukin-1 beta
EP2397498A3 (en) 2005-07-18 2013-11-27 Amgen, Inc Human anti-B7RP1 neutralizing antibodies
US20090317413A1 (en) 2005-11-15 2009-12-24 Cambridge Enterprise Limited Detection of human platelet antigen (hpa) antibodies
CA2636265C (en) * 2006-01-03 2016-07-12 Tto Nord As Preparation useful for, and method for treatment of neonatal alloimmune thrombocytopenia (nait)
ATE468351T1 (de) 2006-02-07 2010-06-15 Diagnostische Forsch Stiftung Peptidaptamer zum neutralisieren der bindung von platelet-antigen-spezifischen antikörpern und diagnostische und therapeutische anwendungen, die dieses enthalten
WO2007102383A1 (en) 2006-02-28 2007-09-13 Oncotherapy Science, Inc. Methods for damaging cells using effector functions of anti-epha4 antibodies
EP2006304A1 (en) 2007-06-22 2008-12-24 Stiftung Für Diagnostische Forschung Anti-HPA-5b monoclonal antibody
JP5602426B2 (ja) 2007-05-25 2014-10-08 日本赤十字社 新規GPIIIa遺伝子
EP2025685B1 (en) 2007-08-15 2013-06-19 Canadian Blood Services Monoclonal antibodies against BETA3 integrins
ES2740051T3 (es) 2008-12-31 2020-02-05 Bharat Serums & Vaccines Ltd Anticuerpos monoclonales anti-RHD
CN101892314B (zh) 2010-06-22 2012-04-18 天津市秀鹏生物技术开发有限公司 用于检测人血小板同种抗原基因的引物组及试剂盒
ES2657236T3 (es) 2013-04-26 2018-03-02 Davos Diagnostics Ag Tipificaciones de aloantígenos plaquetarios y pruebas de anticuerpos plaquetarios

Also Published As

Publication number Publication date
AU2015239606A1 (en) 2016-10-20
MX2016012620A (es) 2017-04-06
CA2943857C (en) 2023-07-11
PT3126391T (pt) 2019-11-27
NZ724772A (en) 2023-03-31
EP3126391A1 (en) 2017-02-08
EP3126391B1 (en) 2019-08-21
RU2016142718A (ru) 2018-05-07
AU2015239606C1 (en) 2020-08-27
ES2757596T3 (es) 2020-04-29
WO2015150417A1 (en) 2015-10-08
IL247988B1 (en) 2024-03-01
SI3126391T1 (sl) 2020-04-30
IL247988A0 (en) 2016-11-30
PL3126391T3 (pl) 2020-05-18
RS59704B1 (sr) 2020-01-31
US11725063B2 (en) 2023-08-15
CY1122728T1 (el) 2021-03-12
CA2943857A1 (en) 2015-10-08
ME03655B (me) 2020-07-20
BR112016022508A2 (pt) 2017-10-10
RU2688627C2 (ru) 2019-05-22
HUE047455T2 (hu) 2020-04-28
RU2016142718A3 (da) 2018-10-18
AU2015239606B2 (en) 2020-06-04
US20210189005A1 (en) 2021-06-24
LT3126391T (lt) 2020-02-10
US10882919B2 (en) 2021-01-05
US20170121422A1 (en) 2017-05-04
HRP20192097T1 (hr) 2020-04-03
IL247988B2 (en) 2024-07-01

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