DK3071704T3 - System og fremgangsmåde til sortering af sperm - Google Patents

System og fremgangsmåde til sortering af sperm Download PDF

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Publication number
DK3071704T3
DK3071704T3 DK14864395.0T DK14864395T DK3071704T3 DK 3071704 T3 DK3071704 T3 DK 3071704T3 DK 14864395 T DK14864395 T DK 14864395T DK 3071704 T3 DK3071704 T3 DK 3071704T3
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DK
Denmark
Prior art keywords
sorting sperm
sperm
sorting
Prior art date
Application number
DK14864395.0T
Other languages
English (en)
Inventor
Utkan Demirci
Waseem Asghar
Original Assignee
Brigham & Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53180097&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3071704(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Brigham & Womens Hospital Inc filed Critical Brigham & Womens Hospital Inc
Application granted granted Critical
Publication of DK3071704T3 publication Critical patent/DK3071704T3/da

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/06—Bioreactors or fermenters specially adapted for specific uses for in vitro fertilization
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/061—Sperm cells, spermatogonia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0612—Germ cells sorting of gametes, e.g. according to sex or motility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4005—Concentrating samples by transferring a selected component through a membrane
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • G01N15/01—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G01N2001/4088—Concentrating samples by other techniques involving separation of suspended solids filtration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N2015/0003—Determining electric mobility, velocity profile, average speed or velocity of a plurality of particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G01N2015/1028—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/367—Infertility, e.g. sperm disorder, ovulatory dysfunction
DK14864395.0T 2013-11-20 2014-11-19 System og fremgangsmåde til sortering af sperm DK3071704T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361906740P 2013-11-20 2013-11-20
PCT/US2014/066405 WO2015077333A1 (en) 2013-11-20 2014-11-19 System and method for sperm sorting

Publications (1)

Publication Number Publication Date
DK3071704T3 true DK3071704T3 (da) 2022-04-19

Family

ID=53180097

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14864395.0T DK3071704T3 (da) 2013-11-20 2014-11-19 System og fremgangsmåde til sortering af sperm

Country Status (10)

Country Link
US (7) US10422737B2 (da)
EP (3) EP4269984A3 (da)
JP (2) JP6524082B2 (da)
CN (4) CN115595240A (da)
AU (1) AU2014353050B2 (da)
CA (1) CA2931201C (da)
DK (1) DK3071704T3 (da)
ES (1) ES2915379T3 (da)
PL (1) PL3071704T3 (da)
WO (1) WO2015077333A1 (da)

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CN105188933B (zh) * 2013-05-03 2017-09-19 莫迪利蒂康特公司 用于分析细胞运动性的设备
DK3071704T3 (da) 2013-11-20 2022-04-19 Brigham & Womens Hospital Inc System og fremgangsmåde til sortering af sperm
EP3310898B1 (en) * 2015-06-22 2021-11-03 The Brigham and Women's Hospital, Inc. Home evaluation of the quality of semen samples
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CN108495922B (zh) * 2016-01-22 2022-10-28 小利兰·斯坦福大学托管委员会 一种用于从未处理的***中选择性分选高活动和形态正常的***的微流体装置
AR107746A1 (es) * 2017-02-24 2018-05-30 Herberto Ernesto Hector Repetto Dispositivo y método de separación de células móviles
CN107099444B (zh) * 2017-04-17 2024-04-09 隗慧林 ***分选芯片、***检测设备及***检测方法
EP3687416A1 (en) * 2017-09-29 2020-08-05 Nanovare SAS Devices and methods for analysis of male infertility
KR101966223B1 (ko) * 2017-09-29 2019-04-05 한국과학기술연구원 정자 관찰 구조체 및 이를 포함하는 정자 관찰 시스템
US11517900B2 (en) 2017-10-27 2022-12-06 University Of Utah Research Foundation Microfluidic system for sperm separation and enrichment from various types of sperm samples
FR3081292B1 (fr) * 2018-05-24 2020-06-05 Imv Technologies Dispositif de collecte de semence animale
US20210178394A1 (en) * 2018-08-21 2021-06-17 Florida Atlantic University Board Of Trustees Systems and methods for sperm selection
CN110874821B (zh) * 2018-08-31 2023-05-30 赛司医疗科技（北京）有限公司 一种自动过滤***中非***成分的图像处理方法
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JP2022504466A (ja) * 2018-10-08 2022-01-13 バイオエレクトロニカ コーポレイション 試料を光学的に処理するためのシステムおよび方法
EP4008279A3 (en) 2018-10-10 2022-09-28 InnoMed Seven L.L.C. System and method for intrauterine insemination
EP3904937A4 (en) * 2018-12-28 2022-09-21 Olympus Corporation MICROSCOPE SYSTEM
CN110172390A (zh) * 2019-05-30 2019-08-27 南京精竞生物科技有限公司 一种高活力***筛选微流控装置
CN110551618B (zh) * 2019-09-27 2021-04-23 中国科学技术大学 一种***分选装置
WO2021124111A1 (en) * 2019-12-16 2021-06-24 King Abdullah University Of Science And Technology Microfluidic device for highly motile sperm selection
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CN111323361B (zh) * 2020-03-17 2022-05-10 南通大学 一种快速分离***头、***尾和正常有活力***的方法
CN112662550B (zh) * 2020-10-16 2023-11-10 熹微(苏州)生物医药科技有限公司 一种从***样本中分离***的装置和方法
CN112980661A (zh) * 2021-02-01 2021-06-18 广州蓝日生物科技有限公司 一种***优选装置及其操作方法
AR125716A1 (es) 2021-04-21 2023-08-09 Selectivity S A S Un dispositivo de inseminación y un proceso que lo utiliza
EP4130228A3 (en) * 2021-08-02 2023-02-15 Bonraybio Co., Ltd. Sperm sorting device and method
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Also Published As

Publication number Publication date
EP4269984A2 (en) 2023-11-01
EP4039817A1 (en) 2022-08-10
US20230417647A1 (en) 2023-12-28
JP2019141081A (ja) 2019-08-29
EP3071704A4 (en) 2017-10-04
CN115369011A (zh) 2022-11-22
CN105960463A (zh) 2016-09-21
CN115595240A (zh) 2023-01-13
JP6850824B2 (ja) 2021-03-31
PL3071704T3 (pl) 2022-07-25
EP3071704A1 (en) 2016-09-28
WO2015077333A1 (en) 2015-05-28
CA2931201C (en) 2021-07-13
JP6524082B2 (ja) 2019-06-05
CN117025364A (zh) 2023-11-10
US20230332996A1 (en) 2023-10-19
US20190383722A1 (en) 2019-12-19
US10422737B2 (en) 2019-09-24
US20210270715A1 (en) 2021-09-02
CA2931201A1 (en) 2015-05-28
US20240027320A1 (en) 2024-01-25
AU2014353050B2 (en) 2019-10-03
AU2014353050A1 (en) 2016-06-09
US20160290913A1 (en) 2016-10-06
EP3071704B1 (en) 2022-03-30
US11788943B2 (en) 2023-10-17
US11841309B2 (en) 2023-12-12
US11009444B2 (en) 2021-05-18
EP4269984A3 (en) 2024-02-07
US20220364975A1 (en) 2022-11-17
US11946846B2 (en) 2024-04-02
JP2016538858A (ja) 2016-12-15
US11709122B2 (en) 2023-07-25
ES2915379T3 (es) 2022-06-22

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