DK2994488T3 - Anvendelse af c5ar-antagonister - Google Patents
Anvendelse af c5ar-antagonister Download PDFInfo
- Publication number
- DK2994488T3 DK2994488T3 DK14724691.2T DK14724691T DK2994488T3 DK 2994488 T3 DK2994488 T3 DK 2994488T3 DK 14724691 T DK14724691 T DK 14724691T DK 2994488 T3 DK2994488 T3 DK 2994488T3
- Authority
- DK
- Denmark
- Prior art keywords
- c5ar antagonists
- c5ar
- antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13166973 | 2013-05-08 | ||
US201361821336P | 2013-05-09 | 2013-05-09 | |
EP14151982 | 2014-01-21 | ||
PCT/EP2014/059477 WO2014180961A1 (en) | 2013-05-08 | 2014-05-08 | Use of c5ar antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2994488T3 true DK2994488T3 (da) | 2022-10-03 |
Family
ID=51866834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14724691.2T DK2994488T3 (da) | 2013-05-08 | 2014-05-08 | Anvendelse af c5ar-antagonister |
Country Status (6)
Country | Link |
---|---|
US (2) | US20160060351A1 (da) |
EP (1) | EP2994488B1 (da) |
JP (1) | JP2016523829A (da) |
CN (1) | CN105392803B (da) |
DK (1) | DK2994488T3 (da) |
WO (1) | WO2014180961A1 (da) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2012266487B2 (en) | 2011-06-06 | 2016-12-08 | Novo Nordisk A/S | Therapeutic antibodies |
CA3220371A1 (en) | 2014-09-29 | 2016-04-07 | Chemocentryx, Inc. | Processes and intermediates in the preparation of c5ar antagonists |
EP3349773A4 (en) * | 2015-09-14 | 2019-05-01 | Cincinnati Children's Hospital Medical Center | METHODS AND COMPOSITIONS FOR THE TREATMENT OF LEFT-HALF DISEASE VIA C5A RECEPTOR MODULATION |
CN106957366B (zh) * | 2016-01-12 | 2022-02-01 | 上海昀怡健康科技发展有限公司 | 一种C5aR抗体及其制备方法和应用 |
JP7339733B2 (ja) | 2016-01-14 | 2023-09-06 | ケモセントリックス,インコーポレイティド | C3腎症を処置する方法 |
US10376595B2 (en) | 2017-04-03 | 2019-08-13 | Inflarx Gmbh | Treatment of inflammatory diseases with inhibitors of C5a activity |
CA3066689C (en) * | 2017-06-23 | 2024-01-16 | Inflarx Gmbh | Treatment of inflammatory diseases with inhibitors of c5a activity |
CN113574072B (zh) * | 2019-03-14 | 2023-12-12 | 莫佛塞斯公司 | 靶向C5aR的抗体 |
TW202140553A (zh) | 2020-01-13 | 2021-11-01 | 美商威特拉公司 | C5ar1抗體分子及其用途 |
CN116615454A (zh) | 2020-08-12 | 2023-08-18 | 先天制药公司 | 采用艾朵利单抗的皮下抗c5ar拮抗剂治疗方案 |
AU2021410668A1 (en) * | 2020-12-21 | 2023-07-06 | Chemocentryx, Inc. | Treatment of c3 glomerulopathy using a c5a inhibitor |
JP2024502863A (ja) | 2021-01-13 | 2024-01-23 | ビステラ, インコーポレイテッド | ヒト化補体5a受容体1抗体及びその使用方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA04001301A (es) * | 2001-08-17 | 2004-07-08 | Tanox Inc | Inhibidores de la ruta del complemento que se unen a c5 y c5a son evitar la formacion de c5b. |
ES2561828T3 (es) * | 2002-01-25 | 2016-03-01 | Novo Nordisk A/S | Anticuerpos monoclonales contra bucles extracelulares de C5aR |
AU2002952086A0 (en) * | 2002-10-16 | 2002-11-07 | The University Of Queensland | Treatment of osteoarthritis |
US7807389B2 (en) * | 2003-03-14 | 2010-10-05 | University Of Rochester | Methods and compositions related to joint inflammation diseases |
WO2007055374A1 (ja) * | 2005-11-14 | 2007-05-18 | Mitsubishi Tanabe Pharma Corporation | 骨粗鬆症治療剤 |
CN104193824A (zh) * | 2008-02-20 | 2014-12-10 | G2炎症私人有限公司 | 人源化抗-C5aR抗体 |
US9040507B2 (en) * | 2008-06-02 | 2015-05-26 | Novelmed Therapeutics, Inc. | Method for treating inflammatory conditions |
US20090324585A1 (en) * | 2008-06-12 | 2009-12-31 | The Trustees of the Leland Standford Junior University | Complement inhibitory agents as therapeutics in posttraumatic and degenerative arthritis |
-
2014
- 2014-05-08 US US14/888,141 patent/US20160060351A1/en not_active Abandoned
- 2014-05-08 CN CN201480025887.8A patent/CN105392803B/zh active Active
- 2014-05-08 EP EP14724691.2A patent/EP2994488B1/en active Active
- 2014-05-08 JP JP2016512383A patent/JP2016523829A/ja active Pending
- 2014-05-08 WO PCT/EP2014/059477 patent/WO2014180961A1/en active Application Filing
- 2014-05-08 DK DK14724691.2T patent/DK2994488T3/da active
-
2019
- 2019-03-26 US US16/365,496 patent/US20200017598A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2994488A1 (en) | 2016-03-16 |
US20200017598A1 (en) | 2020-01-16 |
EP2994488B1 (en) | 2022-07-13 |
CN105392803B (zh) | 2019-12-06 |
JP2016523829A (ja) | 2016-08-12 |
CN105392803A (zh) | 2016-03-09 |
WO2014180961A1 (en) | 2014-11-13 |
US20160060351A1 (en) | 2016-03-03 |
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