DK299087D0 - PROTEINS AND DERIVATIVES THEREOF - Google Patents
PROTEINS AND DERIVATIVES THEREOFInfo
- Publication number
- DK299087D0 DK299087D0 DK299087A DK299087A DK299087D0 DK 299087 D0 DK299087 D0 DK 299087D0 DK 299087 A DK299087 A DK 299087A DK 299087 A DK299087 A DK 299087A DK 299087 D0 DK299087 D0 DK 299087D0
- Authority
- DK
- Denmark
- Prior art keywords
- proteins
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/7455—Thrombomodulin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK299087A DK299087D0 (en) | 1987-06-12 | 1987-06-12 | PROTEINS AND DERIVATIVES THEREOF |
JP63505229A JPH03503757A (en) | 1987-06-12 | 1988-06-09 | Proteins and their derivatives |
PCT/DK1988/000089 WO1988009811A1 (en) | 1987-06-12 | 1988-06-09 | Proteins and derivatives thereof |
EP88905725A EP0365568A1 (en) | 1987-06-12 | 1988-06-09 | Proteins and derivatives thereof |
DK627389A DK162169C (en) | 1987-06-12 | 1989-12-12 | RECOMBINATE PROTEINS WITH THROMBOMODULIN ACTIVITY, DNA CONSTRUCTIONS CODING THEREOF, VECTORS, CELLS AND PROCEDURES FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS CONTAINING THE PROTEINES AND THE PROTEINES CONTAINING THE PROTEINES AND THE PROTEINES CONTAINING THE PROTEINES AND THE PROTEINES CONTAINING THE PROTEINS, AND THE |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK299087A DK299087D0 (en) | 1987-06-12 | 1987-06-12 | PROTEINS AND DERIVATIVES THEREOF |
Publications (1)
Publication Number | Publication Date |
---|---|
DK299087D0 true DK299087D0 (en) | 1987-06-12 |
Family
ID=8117912
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK299087A DK299087D0 (en) | 1987-06-12 | 1987-06-12 | PROTEINS AND DERIVATIVES THEREOF |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0365568A1 (en) |
JP (1) | JPH03503757A (en) |
DK (1) | DK299087D0 (en) |
WO (1) | WO1988009811A1 (en) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2766473B2 (en) * | 1987-01-08 | 1998-06-18 | 旭化成工業株式会社 | Peptide promoting the activation of protein C by thrombin |
US4912207A (en) * | 1987-05-06 | 1990-03-27 | Washington University | DNA clone of human thrombomodulin and portions thereof |
WO1990010081A1 (en) * | 1989-02-17 | 1990-09-07 | Codon | Soluble analogs of thrombomodulin |
US6063763A (en) * | 1989-04-28 | 2000-05-16 | Schering Aktiengesellschaft | Protease-resistant thrombomodulin analogs |
US6239101B1 (en) | 1989-07-05 | 2001-05-29 | Oklahoma Medical Research Foundation | Thrombin binding polypeptides |
CA2022713A1 (en) * | 1989-08-11 | 1991-02-12 | Nils U. Bang | Human thrombomodulin derivatives |
CA2065409C (en) * | 1990-06-27 | 2002-05-14 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant polypeptides |
KR930008093B1 (en) * | 1990-08-03 | 1993-08-25 | 아사히가세이고오교 가부시끼가이샤 | New polypeptide and its composition |
CA2648350A1 (en) * | 1990-08-15 | 1992-03-05 | Schering Aktiengesellschaft | Superior thrombomodulin analogs for pharmaceutical use |
ES2220905T3 (en) * | 1992-02-05 | 2004-12-16 | Paion Gmbh | PROTEASE RESISTANT THROMBOMODULIN ANALOG. |
US5945275A (en) * | 1994-10-18 | 1999-08-31 | Corvas International, Inc. | Nematode-extracted anticoagulant protein |
US5872098A (en) * | 1995-06-05 | 1999-02-16 | Corvas International, Inc. | Nematode-extracted anticoagulant protein |
NZ296648A (en) * | 1994-10-18 | 2001-05-25 | Corvas Int Inc | Nematode-extracted serine protease inhibitors and anticoagulant proteins |
US5863894A (en) * | 1995-06-05 | 1999-01-26 | Corvas International, Inc. | Nematode-extracted anticoagulant protein |
US5866543A (en) * | 1995-06-05 | 1999-02-02 | Corvas International, Inc. | Nematode-extracted anticoagulant protein |
US5866542A (en) * | 1994-10-18 | 1999-02-02 | Corvas International, Inc. | Nematode-extracted anticoagulant protein |
CA2202351A1 (en) * | 1994-10-18 | 1996-04-25 | George Phillip Vlasuk | Nematode-extracted serine protease inhibitors and anticoagulant proteins |
JPH11299487A (en) * | 1996-04-03 | 1999-11-02 | Asahi Chem Ind Co Ltd | New gene |
US7579000B2 (en) | 2002-05-01 | 2009-08-25 | Bayer Schering Pharma Ag | Tissue factor targeted antibodies as anticoagulants |
KR101013697B1 (en) | 2002-05-01 | 2011-02-10 | 바이엘 쉐링 파마 악티엔게젤샤프트 | Novel Tissue Factor Targeted Thrombomodulin Fusion Proteins as Anticoagulants |
MX2009003384A (en) | 2006-10-06 | 2009-04-08 | Asahi Kasei Pharma Corp | Therapeutic and/or ameliorating agent for disseminated intravascular coagulation. |
WO2008117735A1 (en) | 2007-03-23 | 2008-10-02 | Asahi Kasei Pharma Corporation | Method for producing soluble thrombomodulin of high purity |
US20120165244A1 (en) * | 2008-10-30 | 2012-06-28 | Hua-Lin Wu | Methods for binding lewis y antigen |
JP5722314B2 (en) | 2010-04-30 | 2015-05-20 | 旭化成ファーマ株式会社 | High purity soluble thrombomodulin and method for producing the same |
CA2807749C (en) * | 2010-08-05 | 2023-02-28 | Council Of Scientific & Industrial Research | Protein fusion constructs possessing thrombolytic and anticoagulant properties |
HUE050698T2 (en) | 2011-11-15 | 2020-12-28 | Asahi Kasei Pharma Corp | Medicine for treatment and/or improvement of sepsis |
ES2743767T3 (en) | 2012-05-31 | 2020-02-20 | Univ Kinki | Agent to prevent and / or treat peripheral neuropathic pain caused by an anticancer drug |
WO2020067389A1 (en) | 2018-09-28 | 2020-04-02 | 旭化成ファーマ株式会社 | Medication for alleviating symptoms of peripheral neuropathy caused by anticancer drug and/or suppressing onset of peripheral neuropathy |
AU2019366008B2 (en) | 2018-10-22 | 2023-12-14 | Asahi Kasei Pharma Corporation | Drug for treating and/or improving septicemia associated with coagulation abnormality |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1987000050A1 (en) * | 1985-06-28 | 1987-01-15 | Asahi Kasei Kogyo Kabushiki Kaisha | Novel physiologically active substance having blood coagulation controlling activity |
-
1987
- 1987-06-12 DK DK299087A patent/DK299087D0/en not_active Application Discontinuation
-
1988
- 1988-06-09 JP JP63505229A patent/JPH03503757A/en active Pending
- 1988-06-09 EP EP88905725A patent/EP0365568A1/en not_active Withdrawn
- 1988-06-09 WO PCT/DK1988/000089 patent/WO1988009811A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0365568A1 (en) | 1990-05-02 |
WO1988009811A1 (en) | 1988-12-15 |
JPH03503757A (en) | 1991-08-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHS | Application shelved for other reasons than non-payment |