DK2883954T3 - Peptidbibliotek og anvendelse deraf - Google Patents

Peptidbibliotek og anvendelse deraf Download PDF

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Publication number
DK2883954T3
DK2883954T3 DK13827389.1T DK13827389T DK2883954T3 DK 2883954 T3 DK2883954 T3 DK 2883954T3 DK 13827389 T DK13827389 T DK 13827389T DK 2883954 T3 DK2883954 T3 DK 2883954T3
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DK
Denmark
Prior art keywords
peptid
library
peptid library
Prior art date
Application number
DK13827389.1T
Other languages
English (en)
Inventor
Daisuke Nishimiya
Ryuji Hashimoto
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Application granted granted Critical
Publication of DK2883954T3 publication Critical patent/DK2883954T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047Simultaneous synthesis of different peptide species; Peptide libraries
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1044Preparation or screening of libraries displayed on scaffold proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00Methods of creating libraries, e.g. combinatorial synthesis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK13827389.1T 2012-08-08 2013-08-07 Peptidbibliotek og anvendelse deraf DK2883954T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012176208 2012-08-08
PCT/JP2013/071345 WO2014024914A1 (ja) 2012-08-08 2013-08-07 ペプチド・ライブラリー及びその利用

Publications (1)

Publication Number Publication Date
DK2883954T3 true DK2883954T3 (da) 2020-09-28

Family

ID=50068137

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13827389.1T DK2883954T3 (da) 2012-08-08 2013-08-07 Peptidbibliotek og anvendelse deraf

Country Status (10)

Country Link
US (3) US10550154B2 (da)
EP (2) EP3748001A1 (da)
JP (6) JP6441075B2 (da)
AU (1) AU2013300549B2 (da)
CA (1) CA2881431C (da)
DK (1) DK2883954T3 (da)
ES (1) ES2813867T3 (da)
IL (1) IL237135B (da)
TW (1) TW201410709A (da)
WO (1) WO2014024914A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101744959B1 (ko) * 2014-12-05 2017-06-12 (주)케어젠 피부상태 개선 활성을 갖는 펩타이드 및 이의 용도
CA3047893C (en) * 2016-12-22 2022-11-15 Daiichi Sankyo Company, Limited Spink2 peptide for preventing and/or treating age-related macular degeneration
DE102017114737A1 (de) * 2017-06-30 2019-01-03 Immatics Biotechnologies Gmbh Neue T-Zellrezeptoren und deren Verwendung in Immuntherapie
CN111051339A (zh) * 2017-07-18 2020-04-21 第一三共株式会社 活性mmp-9-结合肽
US11208467B2 (en) * 2017-09-07 2021-12-28 Daiichi Sankyo Company, Limited Peptides inhibiting KLK1, KLK4, or KLK4 and KLK8
TW202015718A (zh) * 2018-06-21 2020-05-01 日商第一三共股份有限公司 視網膜色素變性治療用胜肽
TW202038997A (zh) 2018-11-07 2020-11-01 日商第一三共股份有限公司 胜肽之血中動態改善方法
BR112021008989A2 (pt) * 2018-11-07 2021-08-17 Daiichi Sankyo Company, Limited peptídeo inibidor de klk5
JP7202695B2 (ja) * 2021-03-05 2023-01-12 株式会社ユニバーサルエンターテインメント 遊技機
JP7202696B2 (ja) * 2021-03-05 2023-01-12 株式会社ユニバーサルエンターテインメント 遊技機

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1545692A (en) 1991-03-01 1992-10-06 Protein Engineering Corporation Process for the development of binding mini-proteins
DK0737207T3 (da) * 1994-01-11 2005-01-31 Dyax Corp Inhibitorer for humant plasmin afledt af Kunitz-domæner
US20040209243A1 (en) 2003-01-07 2004-10-21 Andrew Nixon Kunitz domain library
WO2004100988A1 (ja) 2003-05-13 2004-11-25 Mizuo Miyazaki 心保護剤
MX2007014537A (es) * 2005-05-18 2008-02-12 Wyeth Corp Genes de la enfermedad de la leucemia y sus usos.
WO2007038619A2 (en) * 2005-09-27 2007-04-05 Amunix, Inc. Proteinaceous pharmaceuticals and uses thereof
WO2009093119A2 (en) 2008-01-21 2009-07-30 Med Discovery S.A. Use of serine protease inhibitors in the treatment of skin diseases

Also Published As

Publication number Publication date
JP2024038496A (ja) 2024-03-19
JP2023027398A (ja) 2023-03-01
WO2014024914A1 (ja) 2014-02-13
US20150197546A1 (en) 2015-07-16
US10550154B2 (en) 2020-02-04
JP2021035383A (ja) 2021-03-04
TW201410709A (zh) 2014-03-16
CA2881431A1 (en) 2014-02-13
IL237135A0 (en) 2015-04-30
IL237135B (en) 2019-08-29
CA2881431C (en) 2021-10-19
JP6790212B2 (ja) 2020-11-25
EP2883954A4 (en) 2016-03-02
US20220372076A1 (en) 2022-11-24
JP6441075B2 (ja) 2018-12-19
JP2019073510A (ja) 2019-05-16
AU2013300549B2 (en) 2019-04-11
JP7429765B2 (ja) 2024-02-08
JP2020023531A (ja) 2020-02-13
JP7203800B2 (ja) 2023-01-13
US11319345B2 (en) 2022-05-03
EP2883954A1 (en) 2015-06-17
EP2883954B1 (en) 2020-07-08
JPWO2014024914A1 (ja) 2016-07-25
US20200199179A1 (en) 2020-06-25
AU2013300549A1 (en) 2015-03-19
EP3748001A1 (en) 2020-12-09
ES2813867T3 (es) 2021-03-25
JP6603390B2 (ja) 2019-11-06

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