DK2794849T3 - Fremgangsmåde til fremstilling af svækkede salmonellastammer med højt udbytte - Google Patents

Fremgangsmåde til fremstilling af svækkede salmonellastammer med højt udbytte

Info

Publication number
DK2794849T3
DK2794849T3 DK12808264.1T DK12808264T DK2794849T3 DK 2794849 T3 DK2794849 T3 DK 2794849T3 DK 12808264 T DK12808264 T DK 12808264T DK 2794849 T3 DK2794849 T3 DK 2794849T3
Authority
DK
Denmark
Prior art keywords
stums
weaked
salmonella
procedure
manufacture
Prior art date
Application number
DK12808264.1T
Other languages
English (en)
Inventor
Heinz Lubenau
Holger Siede
Renate Janssen
Marco Springer
Original Assignee
Vaximm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaximm Ag filed Critical Vaximm Ag
Application granted granted Critical
Publication of DK2794849T3 publication Critical patent/DK2794849T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001102Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103Receptors for growth factors
    • A61K39/001109Vascular endothelial growth factor receptors [VEGFR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36Adaptation or attenuation of cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q3/00Condition responsive control processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK12808264.1T 2011-12-22 2012-12-21 Fremgangsmåde til fremstilling af svækkede salmonellastammer med højt udbytte DK2794849T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11400061 2011-12-22
PCT/EP2012/005364 WO2013091898A1 (en) 2011-12-22 2012-12-21 Method for producing high yield attenuated salmonella strains

Publications (1)

Publication Number Publication Date
DK2794849T3 true DK2794849T3 (da) 2017-11-06

Family

ID=47458857

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12808264.1T DK2794849T3 (da) 2011-12-22 2012-12-21 Fremgangsmåde til fremstilling af svækkede salmonellastammer med højt udbytte

Country Status (20)

Country Link
US (1) US9493738B2 (da)
EP (1) EP2794849B1 (da)
JP (1) JP6251179B2 (da)
KR (1) KR102015932B1 (da)
CN (1) CN104066834B (da)
AU (1) AU2012359166B2 (da)
BR (1) BR112014015706A2 (da)
CA (1) CA2853656C (da)
DK (1) DK2794849T3 (da)
ES (1) ES2650269T3 (da)
HU (1) HUE035438T2 (da)
IL (1) IL233167A (da)
LT (1) LT2794849T (da)
MX (1) MX355134B (da)
PL (1) PL2794849T3 (da)
RU (1) RU2631924C2 (da)
SG (1) SG11201403525PA (da)
SI (1) SI2794849T1 (da)
WO (1) WO2013091898A1 (da)
ZA (1) ZA201404501B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE046138T2 (hu) * 2012-07-05 2020-02-28 Vaximm Ag DNS vakcina hasnyálmirigyrákos betegekben történõ alkalmazásra
LT3082850T (lt) * 2013-12-18 2019-11-11 Vaximm Gmbh Į msln nukreipta dnr vakcina vėžio imunoterapijai
US20180153976A1 (en) 2015-06-18 2018-06-07 Vaximm Ag Novel cmv pp65 targeting dna vaccine for cancer immunotherapy
CA2989247C (en) 2015-06-18 2023-10-17 Vaximm Ag Vegfr-2 targeting dna vaccine for combination therapy
US10821163B2 (en) * 2016-07-13 2020-11-03 Vaximm Ag Process for the production of a DNA vaccine for cancer immunotherapy
EP3583200A1 (en) * 2017-02-17 2019-12-25 Vaximm AG Novel vegfr-2 targeting immunotherapy approach
WO2020205528A1 (en) * 2019-04-01 2020-10-08 North Carolina State University Probiotic bacteria capable of adaptive response to pomegranate extract and methods of production and use thereof
EP4126022A1 (en) 2020-03-31 2023-02-08 NEC OncoImmunity AS Novel salmonella-based coronavirus vaccine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH542928A (de) * 1971-04-29 1973-10-15 Schweiz Serum & Impfinst Verfahren zur Herstellung einer neuen Typhus-Vakzine
KR930001382B1 (ko) 1990-09-05 1993-02-27 보령신약 주식회사 경구용 장티프스 생균백신 및 그의 제조방법
NZ526786A (en) * 2001-01-03 2006-02-24 Willmar Poultry Co Inc Methods for removal of lipopolysaccharides (LPS) from vaccines for non-human animals
US7094410B2 (en) 2002-03-02 2006-08-22 The Scripps Research Institute DNA vaccine against proliferating endothelial cells and methods of use thereof
WO2005026203A2 (en) * 2003-09-18 2005-03-24 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Dna promoters and anthrax vaccines
WO2010045620A1 (en) * 2008-10-17 2010-04-22 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium capable of eliciting an immune response against streptococcus pneumoniae
CN101985610A (zh) 2010-10-26 2011-03-16 中国人民解放军军事医学科学院微生物流行病研究所 一种伤寒沙门氏菌菌蜕、制备方法及作为递送***的应用

Also Published As

Publication number Publication date
RU2631924C2 (ru) 2017-09-28
SG11201403525PA (en) 2014-10-30
SI2794849T1 (en) 2018-01-31
MX2014007575A (es) 2015-02-05
RU2014130045A (ru) 2016-02-10
CN104066834A (zh) 2014-09-24
IL233167A (en) 2017-08-31
BR112014015706A2 (pt) 2020-10-27
EP2794849A1 (en) 2014-10-29
JP6251179B2 (ja) 2017-12-20
KR102015932B1 (ko) 2019-08-29
EP2794849B1 (en) 2017-08-30
LT2794849T (lt) 2017-12-11
AU2012359166A1 (en) 2014-06-19
WO2013091898A8 (en) 2015-03-12
AU2012359166B2 (en) 2017-08-10
JP2015502162A (ja) 2015-01-22
PL2794849T3 (pl) 2018-02-28
CA2853656C (en) 2020-12-29
KR20140105028A (ko) 2014-08-29
US20140349274A1 (en) 2014-11-27
WO2013091898A1 (en) 2013-06-27
US9493738B2 (en) 2016-11-15
ES2650269T3 (es) 2018-01-17
IL233167A0 (en) 2014-07-31
MX355134B (es) 2018-04-06
ZA201404501B (en) 2016-02-24
HUE035438T2 (en) 2018-05-02
CA2853656A1 (en) 2013-06-27
CN104066834B (zh) 2017-04-19

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